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News  (888)  Resources  (128)  Forum  (209)  
 
Magnetic ForcesMRI Resource Directory:
 - MRI Accidents -
 
Forces can result from the interaction of magnetic fields. Pulsed magnetic field gradients can interact with the main magnetic field during the MRI scan, to produce acoustic noise through the gradient coil.
Magnetic fields attract ferromagnetic objects with forces, which can be a lethal danger if one is hit by an unrestrained object in flight. One could also be trapped between the magnet and a large unrestrained ferromagnetic object or the object could damage the MRI machine.
Access control and personnel awareness are the best preventions of such accidents. The attraction mechanism for ferromagnetic objects is that the magnetic field magnetizes the iron. This induced magnetization reacts with the gradient of the magnetic field to produce an attraction toward the strongest area of the field. The details of this interaction are very dependent on the shape and composition of the attracted object. There is a very rapid increase of force as one approaches a magnet. There is also a torque or twisting force on objects, e.g. a long cylinder (such as a pen or an intracranial aneurysm clip) will tend to align along the magnet's field lines. The torque increases with field strength while the attraction increases with field gradient.
Depending on the magnetic saturation of the object, attraction is roughly proportional to object mass. Motion of conducting objects in magnetic fields can induce eddy currents that can have the effect of opposing the motion.

See also Duty Cycle.

See also the related poll result: 'Most outages of your scanning system are caused by failure of'
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• For this and other aspects of MRI safety see our InfoSheet about MRI Safety.
• Patient-related information is collected in our MRI Patient Information.

 
Further Reading:
  Basics:
How strong are magnets?
   by my.execpc.com    
Magnetic Field of the Strongest Magnet
2003   by hypertextbook.com    
  News & More:
Imaging chain faces regulators after inmate, guard get stuck to MRI machine
Friday, 1 December 2023   by healthimaging.com    
Measuring magnetic force field distributions in microfluidic devices: Experimental and numerical approaches
Saturday, 2 December 2023   by analyticalsciencejournals.onlinelibrary.wiley.com    
Two stuck to MRI machine for 4 hrs
Tuesday, 11 November 2014   by www.mumbaimirror.com    
New imaging project for new applications in cancer diagnostics
Monday, 27 March 2017   by www.news-medical.net    
MRI Safety Resources 
Safety pool - Shielding - Stent - Safety Training - Stimulator pool
 
MultiHance®InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
MultiHance® is a paramagnetic contrast agent for use in diagnostic magnetic resonance imaging (MRI) of the liver and central nervous system. MultiHance® is a small molecular weight chelate, which tightly binds the Gd atom. The substance is excreted partly by the kidneys, partly by the biliary system, which is especially unique.
MultiHance® is indicated, for the detection of focal liver lesions in patients with known or suspected primary liver cancer (e.g. hepatocellular carcinoma) or metastatic disease.
MultiHance® is also indicated in brain MRI and spine MRI where it improves the detection of lesions and provides diagnostic information additional to that obtained with unenhanced MRI.
Gd-BOPTA-enhanced MRA can provide superior vascular signal intensity and SNR, as compared with Gd-DTPA, due to its higher relaxivity, even at lower doses.
1 ml of solution MultiHance® contains: (0.5M) gadobenate dimeglumine 529 mg = gadobenic acid 334 mg + meglumine 195 mg. Viscosity at 37°C: 5.3 mPa

WARNING: NEPHROGENIC SYSTEMIC FIBROSIS Gadolinium-based contrast agents increase the risk for nephrogenic systemic fibrosis (NSF) in patients with acute or chronic severe renal insufficiency (glomerular filtration rate less than 30 mL/min/1.73m2), or acute renal insufficiency of any severity due to the hepato-renal syndrome or in the perioperative liver transplantation period.
Drug Information and Specification
NAME OF COMPOUND
Gadobenate dimeglumine, Gd-BOPTA, E7155
DEVELOPER
CENTRAL MOIETY
Gd2+
CONTRAST EFFECT
T1, predominantly positive enhancement
r1=9.7, r2=12.5, B0=0.5 T
PHARMACOKINETIC
Extracellular, hepatobiliary
1970 mosm/kg
CONCENTRATION
334 mg/ml
DOSAGE
0.05 mmol/kg for Liver MRI
0.1 mmol/kg for CNS MRI
PREPARATION
Solution for injection
INDICATION
CNS, Liver MRI
DEVELOPMENT STAGE
For sale
DISTRIBUTOR
See below
PRESENTATION
Vials of 5, 10, 15 and 20 mL, 50 and 100 mL Multipacks (Pharmacy Bulk Package)
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT
STAGE
DISTRIBUTOR
EU
MultiHance®
for sale
USA
MultiHance®
for sale
Australia
MultiHance®
for sale
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• View the DATABASE results for 'MultiHance®' (9).Open this link in a new window


• View the NEWS results for 'MultiHance®' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Important Drug Warning for Gadolinium-Based Contrast Agents
Wednesday, 12 September 2007   by www.ismrm.org    
MultiHance Package Insert(.pdf)
   by www.fda.gov    
  News & More:
FDA Expands Pediatric Age Range for MultiHance Contrast Agent
Tuesday, 30 January 2018   by www.empr.com    
MAGNETIC RESONANCE IMAGING OF FOCAL LIVER LESIONS(.pdf)
2002
BRACCO DIAGNOSTICS' MULTIHANCE EARNS FDA APPROVAL
Wednesday, 24 November 2004   by salesandmarketingnetwork.com    
MRI Resources 
Resources - PACS - Raman Spectroscopy - Jobs pool - Databases - Spectroscopy
 
Nephrogenic Systemic FibrosisForum -
related threads
 
(NSF) Nephrogenic systemic fibrosis is a rare and highly debilitating disorder that involves extensive thickening and hardening of the skin with fibrotic nodules and plaques.
MRI contrast media have very low side effects, but accumulating data indicate that gadolinium-based contrast agents increase the risk for the development of NSF among patients with severe renal insufficiency or renal dysfunction due to the hepato-renal syndrome or in the perioperative liver transplantation period.
Due to this reason, gadolinium contrast agents are now considered contraindicated in patients with an estimated glomerular filtration rate fewer than 30 mL/min/1.73m2. In these patients, avoid use of gadolinium-based contrast agents unless the diagnostic information is essential and not available with non-contrast enhanced magnetic resonance imaging (MRI).

Recognized or possibly associated factors for NSF:
Severe renal failure;
high dose of gadolinium chelate;
high dose of erythropoietin;
high serum phosphate levels;
high serum calcium levels;
major surgery, infection, vascular event;
history of hypothyroidism;
metabolic acidosis.

When administering a gadolinium-based contrast agent, do not exceed the recommended dose and allow a sufficient period of time for elimination of the contrast medium from the body prior to any readminstration. Screen all patients for renal dysfunction by obtaining a history and/or laboratory tests.

See also Contrast Medium, Adverse Reaction, MRI Risks, MRI Safety, Ionic Intravenous Contrast Agents, Nonionic Intravenous Contrast Agents, and Contraindications.
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• View the DATABASE results for 'Nephrogenic Systemic Fibrosis' (13).Open this link in a new window


• View the NEWS results for 'Nephrogenic Systemic Fibrosis' (8).Open this link in a new window.
 
Further Reading:
  Basics:
Important Drug Warning for Gadolinium-Based Contrast Agents
Wednesday, 12 September 2007   by www.ismrm.org    
European Medicines Agency makes recommendations to minimise risk of nephrogenic systemic fibrosis with gadolinium-containing contrast agents
Friday, 20 November 2009   by www.ema.europa.eu    
Gadolinium-based MR Contrast Agents and Nephrogenic Systemic Fibrosis
Thursday, 1 March 2007   by radiology.rsna.org    
NSF-Active and NSF-Inert Species of Gadolinium: Mechanistic and Clinical Implications
Friday, 27 June 2008   by www.ajronline.org    
  News & More:
Questions and Answers on Gadolinium-Based Contrast Agents
Friday, 9 January 2009   by www.fda.gov    
Searchterm 'AIN' was also found in the following services: 
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News  (888)  Resources  (128)  Forum  (209)  
 
Parallel Imaging TechniqueForum -
related threadsInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
In parallel MR imaging, a reduced data set in the phase encoding direction(s) of k-space is acquired to shorten acquisition time, combining the signal of several coil arrays. The spatial information related to the phased array coil elements is utilized for reducing the amount of conventional Fourier encoding.
First, low-resolution, fully Fourier-encoded reference images are required for sensitivity assessment. Parallel imaging reconstruction in the Cartesian case is efficiently performed by creating one aliased image for each array element using discrete Fourier transformation. The next step then is to create an full FOV image from the set of intermediate images. Parallel reconstruction techniques can be used to improve the image quality with increased signal to noise ratio, spatial resolution, reduced artifacts, and the temporal resolution in dynamic MRI scans.
Parallel imaging algorithms can be divided into 2 main groups:
Image reconstruction produced by each coil (reconstruction in the image domain, after Fourier transform): SENSE (Sensitivity Encoding), PILS (Partially Parallel Imaging with Localized Sensitivity), ASSET.
Reconstruction of the Fourier plane of images from the frequency signals of each coil (reconstruction in the frequency domain, before Fourier transform): GRAPPA.
Additional techniques include SMASH, SPEEDER™, IPAT (Integrated Parallel Acquisition Techniques - derived of GRAPPA a k-space based technique) and mSENSE (an image based enhanced version of SENSE).
 
Images, Movies, Sliders:
 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
SlidersSliders Overview

 
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• View the DATABASE results for 'Parallel Imaging Technique' (12).Open this link in a new window

 
Further Reading:
  Basics:
Parallel MRI Using Multiple Receiver Coils
   by www-math.mit.edu    
Coil Arrays for Parallel MRI: Introduction and Overview.
   by www.mr.ethz.ch    
  News & More:
Cardiac MRI Becoming More Widely Available Thanks to AI and Reduced Exam Times
Wednesday, 19 February 2020   by www.dicardiology.com    
The Effects of Breathing Motion on DCE-MRI Images: Phantom Studies Simulating Respiratory Motion to Compare CAIPIRINHA-VIBE, Radial-VIBE, and Conventional VIBE
Tuesday, 7 February 2017   by www.kjronline.org    
Implementation of Dual-Source RF Excitation in 3 T MR-Scanners Allows for Nearly Identical ADC Values Compared to 1.5 T MR Scanners in the Abdomen
Wednesday, 29 February 2012   by www.plosone.org    
Clinical evaluation of a speed optimized T2 weighted fast spin echo sequence at 3.0 T using variable flip angle refocusing, half-Fourier acquisition and parallel imaging
Wednesday, 25 October 2006
MRI Resources 
IR - Corporations - Diffusion Weighted Imaging - Pregnancy - Lung Imaging - Anatomy
 
Signa 3.0Tâ„¢InfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.MRI Resource Directory:
 - Devices -
 
www.gehealthcare.com/usen/mr/s_excite3/index.html (Signa VH/i 3.0T)
With GE Healthcare leading-edge technology in ultra-high-field imaging. The 3 T VH/i provides a platform for advanced applications in radiology, cardiology, psychology and psychiatry. Real-time image processing lets you acquire multislice whole brain images and map brain functions for research or surgical planning. And the 3 T Signa VH/i is flexible enough to provide clinicians with high performance they require. It can provide not only outstanding features in brain scanning and neuro-system research, but also a wide range of use in scanning breasts, extremities, the spine and the cardiovascular systems.
Device Information and Specification
CLINICAL APPLICATION
Whole body
CONFIGURATION
Cylindrical - high homogeneity
T/R quadrature head, T/R quadrature body, T/R phased array extremity (opt)
SYNCHRONIZATION
ECG/peripheral, respiratory gating
PULSE SEQUENCES
SE, IR, 2D/3D GRE, FGRE, RF-spoiled GRE, FSE, Angiography: 2D/3D TOF, 2D/3D phase contrast vascular
IMAGING MODES
Single, multislice, volume study, fast scan, multi slab, cine, localizer
SINGLE SLICE
100 Images/sec with Reflex100
MULTISLICE
100 Images/sec with Reflex100
1 cm to 40 cm continuous
2D 0.5-100mm in 0.1mm incremental
1280 x 1024
MEASURING MATRIX
128x512 steps 32 phase encode
PIXEL INTENSITY
256 gray levels
55cm
MAGNET WEIGHT
15102 kg incl. cryogen's
H*W*D
260cm x 238cm x 265cm
POWER REQUIREMENTS
480 or 380/415, 3 phase ||
COOLING SYSTEM TYPE
Closed-loop water-cooled grad.
Less than 0.14 L/hr liquid He
STRENGTH
40mT/m
5-GAUSS FRINGE FIELD, radial/axial
5.4 m x 3.2 m
Superconductive + hi order active
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MRI Resources 
NMR - Musculoskeletal and Joint MRI - PACS - Education pool - Claustrophobia - Equipment
 
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