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News  (888)  Resources  (128)  Forum  (209)  
 
Cine SequenceInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
Cine sequences used in cardiovascular MRI are collection of images (usually at the same spatial location) covering of one full period of cardiac cycle or over several periods in order to obtain complete coverage.
The pulse sequence used, is either a standard gradient echo pulse sequence, a segmented data acquisition, a gradient echo EPI sequence or a gradient echo with balanced gradient waveform. In cardiac gating studies it is possible to assign consecutive lines either to different images, yielding a multiphase sequence with as many images as lines, or the lines are grouped together into segments and assigned to the same image. The overall time to acquire such a segment has to be small compared to the RR-interval of the cardiac cycle, i. e. 50 ms, and hence contains typically 8 to 16 image lines.
This strategy is called segmented data acquisition, and has the advantage of reducing overall imaging time for cardiac images so that they can be acquired within a breath hold, but obviously decreasing the temporal resolution of each individual image. This method shows dynamic processes, such as the ejection of blood out of the heart into the aorta, by means of fast imaging and displaying the resulting images in a sequential-loop, the impression of a real-time movie is generated. Ejection fractions and stroke volumes calculated from these cine MRI images in different cardiac axes have been shown to be more accurate than any other imaging modality.

See also Cardiac Gating.
 
Images, Movies, Sliders:
 Angulation of Cardiac Planes Cine Images of Septal Infarct  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Cardiac Infarct Short Axis Cine Overview  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 Infarct 4 Chamber Cine  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 
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Further Reading:
  News & More:
Study Shows Cardiac MRI Use Reduces Adverse Events for Patients with Acute Chest Pain
Monday, 10 June 2013   by www.healthcanal.com    
Study identifies new way to predict prognosis for heart failure patients
Tuesday, 10 December 2013   by medicalxpress.com    
MRI Resources 
Sequences - Databases - Chemistry - Pregnancy - Claustrophobia - MRI Technician and Technologist Career
 
Circle of WillisForum -
related threadsMRI Resource Directory:
 - Anatomy -
 
A large network of interconnecting blood vessels at the base of the brain that when visualized resembles a circle, the arteries effectively act as anastomoses for each other. This means that if any one of the communicating arteries becomes blocked, blood can flow from another part of the circle to ensure that blood flow is not compromised.
The circle of Willis is formed by both the internal carotid arteries, entering the brain from each side and the basilar artery, entering posteriorly. The connection of the vertebral arteries forms the basilar artery. The basilar artery divides into the right and left posterior cerebral arteries. The internal carotid arteries trifurcate into the anterior cerebral artery, middle cerebral artery, and posterior communicating artery. The two anterior cerebral arteries are joined together anteriorly by the anterior communicating artery. The posterior communicating arteries join the posterior cerebral arteries, completing the circle of Willis.
The time of flight angiography MRI technique allows imaging of the circle of Willis without the need of a contrast medium (best results with high field MRI). A cerebrovasular contrast enhanced magnetic resonance angiography (MRA) depicts the circle of Willis in addition to the vessels of the neck (carotid and vertebral arteries) with one bolus injection of a contrast agent.

For Ultrasound Imaging (USI) see Cerebrovascular Ultrasonography at Medical-Ultrasound-Imaging.com.
 
Images, Movies, Sliders:
 CE-MRA of the Carotid Arteries  Open this link in a new window
    
SlidersSliders Overview

 TOF-MRA Circle of Willis Inverted MIP  Open this link in a new window
    

 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
SlidersSliders Overview

 
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• View the DATABASE results for 'Circle of Willis' (5).Open this link in a new window

 
Further Reading:
  News & More:
Magnetic resonance angiography: current status and future directions
Wednesday, 9 March 2011   by www.jcmr-online.com    
MRI Resources 
Chemistry - Health - Shoulder MRI - Lung Imaging - Raman Spectroscopy - Abdominal Imaging
 
Coherence
 
The act of maintaining a constant phase relationship between oscillating waves or rotating objects.
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• View the DATABASE results for 'Coherence' (19).Open this link in a new window

 
Further Reading:
  Basics:
Measuring T1 and T2 Relaxation - Introductory NMR & MRI from Magritek
   by www.azom.com    
Searchterm 'AIN' was also found in the following services: 
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News  (888)  Resources  (128)  Forum  (209)  
 
CoilForum -
related threadsInfoSheet: - Coils - 
Intro, 
Overview, 
etc.MRI Resource Directory:
 - Coils -
 
A coil consists of one or more loops of conductive wire, looped around the core of the coil. Coils are part of the hardware of MRI machines and are used to create a magnetic field or to detect a changing magnetic field by voltage induced in the wire. A coil is usually a physically small antenna.
The perfect coil produces a uniform magnetic field without significant radiation.
Different types of MRI coils are used in MR systems:
Gradient coils are used to produce controlled variations in the main magnetic field (B0) to provide spatial localization of the signals and to apply reversal pulses in some imaging techniques.
MR imaging radio frequency coils to receive and/or transmit the RF signal.
Shim coils provide auxiliary magnetic fields in order to compensate for inhomogeneities in the main magnetic field of the MRI machine.

See also Gradient Coil, Radio Frequency Coil, Hardware and Coil Loading.

See also the related POLL result: '3rd party coils are better than the original manufacturer coils'
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• View the DATABASE results for 'Coil' (193).Open this link in a new window


• View the NEWS results for 'Coil' (11).Open this link in a new window.
 
Further Reading:
  News & More:
3T MRI-Compatible Small Body Array Gets FDA Nod
Monday, 15 January 2024   by www.diagnosticimaging.com    
High-field MRI Coils – that work, superbly, even at 750 MHz
   by www.dotynmr.com    
New superconducting coil improves MRI performance
Wednesday, 20 July 2016   by www.eurekalert.org    
First European fully superconductive coil reaching a magnetic field of 25 Tesla produced
Wednesday, 8 June 2016   by www.news-medical.net    
ScanMed Introduces a Groundbreaking New Orbit and Mandible Array to the MRI Market
Wednesday, 26 March 2014   by www.digitaljournal.com    
MRI coil optimized for imaging of infants gets FDA clearance
Tuesday, 17 April 2012   by www.medcitynews.com    
Low-profile MRI coil company inching toward commercialization
Wednesday, 21 December 2011   by www.medcitynews.com    
High-Resolution Uniform MR Imaging of Finger Joints Using a Dedicated RF Coil at 3 Tesla
Sunday, 31 January 2010   by www.ncbi.nlm.nih.gov    
DOTmed Industry Sector Report: MRI Coil Sales & Service Companies
Thursday, 13 December 2007   by www.dotmed.com    
MRI Resources 
Quality Advice - Blood Flow Imaging - Image Quality - Mobile MRI - Coils - Developers
 
Contrast AgentsForum -
related threadsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Contrast agents are chemical substances introduced to the anatomical or functional region being imaged, to increase the differences between different tissues or between normal and abnormal tissue, by altering the relaxation times. MRI contrast agents are classified by the different changes in relaxation times after their injection.
Positive contrast agents cause a reduction in the T1 relaxation time (increased signal intensity on T1 weighted images). They (appearing bright on MRI) are typically small molecular weight compounds containing as their active element Gadolinium, Manganese, or Iron. All of these elements have unpaired electron spins in their outer shells and long relaxivities.
Some typical contrast agents as gadopentetate dimeglumine, gadoteridol, and gadoterate meglumine are utilized for the central nervous system and the complete body; mangafodipir trisodium is specially used for lesions of the liver and gadodiamide for the central nervous system.
Negative contrast agents (appearing predominantly dark on MRI) are small particulate aggregates often termed superparamagnetic iron oxide (SPIO). These agents produce predominantly spin spin relaxation effects (local field inhomogeneities), which results in shorter T1 and T2 relaxation times.
SPIO's and ultrasmall superparamagnetic iron oxides (USPIO) usually consist of a crystalline iron oxide core containing thousands of iron atoms and a shell of polymer, dextran, polyethyleneglycol, and produce very high T2 relaxivities. USPIOs smaller than 300 nm cause a substantial T1 relaxation. T2 weighted effects are predominant.
A special group of negative contrast agents (appearing dark on MRI) are perfluorocarbons (perfluorochemicals), because their presence excludes the hydrogen atoms responsible for the signal in MR imaging.

The design objectives for the next generation of MR contrast agents will likely focus on prolonging intravascular retention, improving tissue targeting, and accessing new contrast mechanisms. Macromolecular paramagnetic contrast agents are being tested worldwide. Preclinical data shows that these agents demonstrate great promise for improving the quality of MR angiography, and in quantificating capillary permeability and myocardial perfusion.
Ultrasmall superparamagnetic iron oxide (USPIO) particles have been evaluated in multicenter clinical trials for lymph node MR imaging and MR angiography, with the clinical impact under discussion. In addition, a wide variety of vector and carrier molecules, including antibodies, peptides, proteins, polysaccharides, liposomes, and cells have been developed to deliver magnetic labels to specific sites. Technical advances in MR imaging will further increase the efficacy and necessity of tissue-specific MRI contrast agents.

See also Adverse Reaction and Nephrogenic Systemic Fibrosis.

See also the related poll result: 'The development of contrast agents in MRI is'
 
Images, Movies, Sliders:
 Delayed Myocardial Contrast Enhancement from Infarct  Open this link in a new window
      

Courtesy of  Robert R. Edelman
 Left Circumflex Ischemia First-pass Contrast Enhancement  Open this link in a new window
 MR Colonography Gadolinium per Rectum  Open this link in a new window
      

Courtesy of  Robert R. Edelman
 CE MRA of the Aorta  Open this link in a new window
    
SlidersSliders Overview

 
Radiology-tip.comradContrast Agents,  Safety of Contrast Agents
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Medical-Ultrasound-Imaging.comUltrasound Contrast Agents,  Ultrasound Contrast Agent Safety
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• View the DATABASE results for 'Contrast Agents' (122).Open this link in a new window


• View the NEWS results for 'Contrast Agents' (25).Open this link in a new window.
 
Further Reading:
  Basics:
Analysis of MRI contrast agents
Thursday, 17 November 2022   by www.sciencedaily.com    
New guidelines urge caution on use of contrast agents during MR scans
Tuesday, 8 August 2017   by www.dotmed.com    
New Study Sheds Light on Safety of Gadolinium-Based Contrast Agents
Wednesday, 29 November 2017   by www.empr.com    
A safer approach for diagnostic medical imaging
Monday, 29 September 2014   by www.eurekalert.org    
Manganese-based MRI contrast agents: past, present and future
Friday, 4 November 2011   by www.ncbi.nlm.nih.gov    
  News & More:
Brain imaging method may aid mild traumatic brain injury diagnosis
Tuesday, 16 January 2024   by parkinsonsnewstoday.com    
A Targeted Multi-Crystalline Manganese Oxide as a Tumor-Selective Nano-Sized MRI Contrast Agent for Early and Accurate Diagnosis of Tumors
Thursday, 18 January 2024   by www.dovepress.com    
FDA Approves Gadopiclenol for Contrast-Enhanced Magnetic Resonance Imaging
Tuesday, 27 September 2022   by www.pharmacytimes.com    
How to stop using gadolinium chelates for magnetic resonance imaging: clinical-translational experiences with ferumoxytol
Saturday, 5 February 2022   by www.ncbi.nlm.nih.gov    
Estimation of Contrast Agent Concentration in DCE-MRI Using 2 Flip Angles
Tuesday, 11 January 2022   by pubmed.ncbi.nlm.nih.gov    
Manganese enhanced MRI provides more accurate details of heart function after a heart attack
Tuesday, 11 May 2021   by www.news-medical.net    
Gadopiclenol: positive results for Phase III clinical trials
Monday, 29 March 2021   by www.pharmiweb.co    
Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
Friday, 4 December 2020   by www.dovepress.com    
Polysaccharide-Core Contrast Agent as Gadolinium Alternative for Vascular MR
Monday, 8 March 2021   by www.diagnosticimaging.com    
Water-based non-toxic MRI contrast agents
Monday, 11 May 2020   by chemistrycommunity.nature.com    
New method to detect early-stage cancer identified by Georgia State, Emory research team
Friday, 7 February 2020   by www.eurekalert.org    
Researchers Brighten Path for Creating New Type of MRI Contrast Agent
Friday, 7 February 2020   by www.newswise.com    
Manganese-based MRI contrast agent may be safer alternative to gadolinium-based agents
Wednesday, 15 November 2017   by www.eurekalert.org    
Sodium MRI May Show Biomarker for Migraine
Friday, 1 December 2017   by psychcentral.com    
A natural boost for MRI scans
Monday, 21 October 2013   by www.eurekalert.org    
For MRI, time is of the essence A new generation of contrast agents could make for faster and more accurate imaging
Tuesday, 28 June 2011   by scienceline.org    
MRI Resources 
Mass Spectrometry - Examinations - Musculoskeletal and Joint MRI - Developers - Cochlear Implant - Safety Training
 
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