Short name: Dy-DOTA-4AmCE, central moiety: Dy2+, contrast effect: T2*enhanced
Dy-DOTA-4AmCE, a macrocyclic complex is characterized by a very slow water exchange, a complex compared with several Dy-DTPA derivatives known for their efficacy as T2 contrast agents at high magnetic fields.
(TrueFISP) True fast imaging with steady state precession is a coherent technique that uses a fully balanced gradient waveform. The image contrast with TrueFISP is determined by T2*//T1 properties and mostly depending on TR. The speed and relative motion insensitivity of acquisition help to make the technique reliable, even in patients who have difficulty with holding their breath.
Recent advances in gradienthardware have led to a decreased minimum TR. This combined with improved field shimming capabilities and signal to noise ratio, has allowed TrueFISP imaging to become practical for whole-body applications. There's mostly T2* weighting. With the used ultrashort TR-times T1 weighting is almost impossible. One such application is cardiaccine MR with high myocardium-blood contrast.
Spatial and temporal resolution can be substantially improved with this technique, but contrast on the basis of the ratio of T2* to T1 is not sufficiently high in soft tissues. By providing T1 contrast, TrueFISP could then document the enhancement effects of T1 shortening contrast agents. These properties are useful for the anatomical delineation of brain tumors and normal structures. With an increase in SNR ratio with minimum TR, TrueFISP could also depict the enhancement effect in myoma uteri.
True FSIP is a technique that is well suited for cardiacMR imaging. The imaging time is shorter and the contrast between the blood and myocardium is higher than that of FLASH.
Ferric ammonium citrate is a complex salt of indefinite composition that contains varying amounts of iron, that is obtained as red crystals or a brownish yellow powder or as green crystals or powder, and that was used formerly in medicine for treating iron-deficiency anaemia.
Solutions (e.g. corn oil emulsion) of ferric ammonium citrate (e.g., FerriSeltz, Geritol) can be used as positive oral contrast agents in MRI. Ferric ammonium citrate is safe and effective in humans, but has minor side effects.
Ferristene is a superparamagnetic agent that has been used as a magnetic iron particle solution for gastrointestinal use as a negative contrast agent with 23.4 Fe/200ml required concentration.