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Sample Imperfection (Artifact)InfoSheet: - Artifacts - 
Case Studies, 
Reduction Index, 
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 - Artifacts -
 
Quick Overview
Artifact Information
NAME
Sample imperfection
DESCRIPTION
Shifts of the signal in the phase encoding direction
REASON
Distorting the k-space trajectory, reduced bandwidth
HELP
Fat suppression, more excitations
Artifacts either by distorting the k-space trajectory (i.e. due to imperfect shimming) or as a consequence of the reduced bandwidth in the phase encode direction, commonly with EPI sequences.
While a standard spin warp-based sequence has an infinitely large bandwidth in the phase encode direction (about 1 or 2 kH), the bandwidth in EPI is related to the time between the gradient echoes (about a millisecond).
Hence even small frequency offsets can result in significant shifts of the signal in the phase encoding direction. Segmentation can introduce ghosting if there are significant difference in the amplitude and phase of the signal. This can be a particular problem when trying to acquire the segments in rapid succession.
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Image Guidance
Suitable choices of excitation schemes and/or subsequent correction can help to reduce this artifact. The signal from fat can easily be offset by a large fraction of the FOV, and must be suppressed. The effect of frequency offsets can be reduced by collecting data with more than one excitation, which effectively increases the bandwidth in the phase encoding direction.
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Refocused Gradient Echo SequenceInfoSheet: - Sequences - 
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Refocused GRE sequences use a refocusing gradient in the phase encoding direction during the end module to maximize (refocus) remaining xy- (transverse) magnetization at the time when the next excitation is due, while the other two gradients are, in any case, balanced.
When the next excitation pulse is sent into the system with an opposed phase, it tilts the magnetization in the α direction. As a result the z-magnetization is again partly tilted into the xy-plane, while the remaining xy-magnetization is tilted partly into the z-direction.
Companies use different acronyms to describe certain techniques.

Different terms for these gradient echo pulse sequences
R-GRE Refocused Gradient Echo,
FAST Fourier Acquired Steady State,
FFE Fast Field echo,
FISP Fast Imaging with Steady State Precession,
F-SHORT SHORT Repetition Technique Based on Free Induction Decay,
GFEC Gradient Field Echo with Contrast,
GRASS Gradient Recalled Acquisition in Steady State,
ROAST Resonant Offset Averaging in the Steady State,
SSFP Steady State Free Precession.
STERF Steady State Technique with Refocused FID

In this context, 'contrast' refers to the pulse sequence, it does not mean enhancement with a contrast agent.
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Partial Fourier Technique
 
The partial Fourier technique is a modification of the Fourier transformation imaging method used in MRI in which the symmetry of the raw data in k-space is used to reduce the data acquisition time by acquiring only a part of k-space data.
The symmetry in k-space is a basic property of Fourier transformation and is called Hermitian symmetry. Thus, for the case of a real valued function g, the data on one half of k-space can be used to generate the data on the other half.
Utilization of this symmetry to reduce the acquisition time depends on whether the MRI problem obeys the assumption made above, i.e. that the function being characterized is real.
The function imaged in MRI is the distribution of transverse magnetization Mxy, which is a vector quantity having a magnitude, and a direction in the transverse plane. A convenient mathematical notation is to use a complex number to denote a vector quantity such as the transverse magnetization, by assigning the x'-component of the magnetization to the real part of the number and the y'-component to the imaginary part. (Sometimes, this mathematical convenience is stretched somewhat, and the magnetization is described as having a real component and an imaginary component. Physically, the x' and y' components of Mxy are equally 'real' in the tangible sense.)
Thus, from the known symmetry properties for the Fourier transformation of a real valued function, if the transverse magnetization is entirely in the x'-component (i.e. the y'-component is zero), then an image can be formed from the data for only half of k-space (ignoring the effects of the imaging gradients, e.g. the readout- and phase encoding gradients).
The conditions under which Hermitian symmetry holds and the corrections that must be applied when the assumption is not strictly obeyed must be considered.
There are a variety of factors that can change the phase of the transverse magnetization:
Off resonance (e.g. chemical shift and magnetic field inhomogeneity cause local phase shifts in gradient echo pulse sequences. This is less of a problem in spin echo pulse sequences.
Flow and motion in the presence of gradients also cause phase shifts.
Effects of the radio frequency RF pulses can also cause phase shifts in the image, especially when different coils are used to transmit and receive.
Only, if one can assume that the phase shifts are slowly varying across the object (i.e. not completely independent in each pixel) significant benefits can still be obtained. To avoid problems due to slowly varying phase shifts in the object, more than one half of k-space must be covered. Thus, both sides of k-space are measured in a low spatial frequency range while at higher frequencies they are measured only on one side. The fully sampled low frequency portion is used to characterize (and correct for) the slowly varying phase shifts.
Several reconstruction algorithms are available to achieve this. The size of the fully sampled region is dependent on the spatial frequency content of the phase shifts. The partial Fourier method can be employed to reduce the number of phase encoding values used and therefore to reduce the scan time. This method is sometimes called half-NEX, 3/4-NEX imaging, etc. (NEX/NSA). The scan time reduction comes at the expense of signal to noise ratio (SNR).
Partial k-space coverage is also useable in the readout direction. To accomplish this, the dephasing gradient in the readout direction is reduced, and the duration of the readout gradient and the data acquisition window are shortened.
This is often used in gradient echo imaging to reduce the echo time (TE). The benefit is at the expense in SNR, although this may be partly offset by the reduced echo time. Partial Fourier imaging should not be used when phase information is eligible, as in phase contrast angiography.

See also acronyms for 'partial Fourier techniques' from different manufacturers.
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