(MRA) Magnetic resonance angiography is a medical imaging technique to visualize blood filled structures, including arteries, veins and the heart chambers. This MRI technique creates soft tissue contrast between blood vessels and surrounding tissues primarily created by flow, rather than displaying the vessel lumen. There are bright blood and black blood MRA techniques, named according to the appearance of the blood vessels. With this different MRA techniques both, the blood flow and the condition of the blood vessel walls can be seen. Flow effects in MRI can produce a range of artifacts. MRA takes advantage of these artifacts to create predictable image contrast due to the nature of flow.
Technical parameters of the MRA sequence greatly affect the sensitivity of the images to flow with different velocities or directions, turbulent flow and vessel size.
This are the three main types of MRA:
All angiographic techniques differentially enhance vascular MR signal. The names of the bright blood techniques TOF and PCA reflect the physical properties of flowing blood that were exploited to make the vessels appear bright. Contrast enhanced magnetic resonance angiography creates the angiographic effect by using an intravenously administered MR contrast agent to selectively shorten the T1 of blood and thereby cause the vessels to appear bright on T1 weighted images.
MRA images optimally display areas of constant blood flow-velocity, but there are many situations where the flow within a voxel has non-uniform speed or direction. In a diseased vessel these patterns are even more complex. Similar loss of streamline flow occurs at all vessel junctions and stenoses, and in regions of mural thrombosis. It results in a loss of signal, due to the loss of phase coherence between spins in the voxel.
This signal loss, usually only noticeable distal to a stenosis, used to be an obvious characteristic of MRA images. It is minimized by using small voxels and the shortest possible TE. Signal loss from disorganized flow is most noticeable in TOF imaging but also affects the PCA images.
Indications to perform a magnetic resonance angiography (MRA):
Conventional angiography or computerized tomography angiography (CT angiography) may be needed after MRA if a problem (such as an aneurysm) is present or if surgery is being considered.

See also Magnetic Resonance Imaging MRI.

(MRI) Magnetic resonance imaging is a noninvasive medical imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field and body tissue to obtain images of slices/planes from inside the body. These magnets generate fields from approx. 2000 times up to 30000 times stronger than that of the Earth. The use of nuclear magnetic resonance principles produces extremely detailed pictures of the body tissue without the need for x-ray exposure and gives diagnostic information of various organs.
Measured are mobile hydrogen nuclei (protons are the hydrogen atoms of water, the 'H' in H20), the majority of elements in the body. Only a small part of them contribute to the measured signal, caused by their different alignment in the magnetic field. Protons are capable of absorbing energy if exposed to short radio wave pulses (electromagnetic energy) at their resonance frequency. After the absorption of this energy, the nuclei release this energy so that they return to their initial state of equilibrium.
This transmission of energy by the nuclei as they return to their initial state is what is observed as the MRI signal. The subtle differing characteristic of that signal from different tissues combined with complex mathematical formulas analyzed on modern computers is what enables MRI imaging to distinguish between various organs. Any imaging plane, or slice, can be projected, and then stored or printed.
The measured signal intensity depends jointly on the spin density and the relaxation times (T1 time and T2 time), with their relative importance depending on the particular imaging technique and choice of interpulse times. Any motion such as blood flow, respiration, etc. also affects the image brightness.
Magnetic resonance imaging is particularly sensitive in assessing anatomical structures, organs and soft tissues for the detection and diagnosis of a broad range of pathological conditions. MRI pictures can provide contrast between benign and pathological tissues and may be used to stage cancers as well as to evaluate the response to treatment of malignancies. The need for biopsy or exploratory surgery can be eliminated in some cases, and can result in earlier diagnosis of many diseases.

See also MRI History and Functional Magnetic Resonance Imaging (fMRI).

(NPW / PNW - Phase No Wrap) If the receiving RF coil is sensitive to tissue signal arising from outside the desired FOV, this undesired signal may be incorrectly mapped, or wrapped back to a location within the image and is seen as artifact. This problem occurs in the phase encoding direction, where the phases of signal-bearing tissues outside of the FOV in the y-direction are a replication of the phases that are encoded within the FOV.
A user-selectable parameter maps this signal to its correct location outside the FOV, then discards any signal from outside the FOV before displaying the image. No phase wrap works by filling k-space to the same extent, using twice as many phase encoding steps. In order to be able to choose this parameter, in most cases more than an average is necessary.

See Foldover Suppression and Oversampling.

Oversampling is the increase in data to avoid aliasing and wrap around artifacts. Aliasing is the incorrectly mapping of tissue signal from outside the FOV to a location inside the FOV. This is caused by the fact, that the acquired k-space frequency data is not sampled density enough.
Oversampling in frequency direction, done by increasing the sampling frequency, prevents this aliasing artifact. The proper frequency based on the sampling theorem (Shannon sampling theorem/Nyquist sampling theorem) must be at least twice the frequency of each frequency component in the incoming signal. All frequency components above this limit will be aliased to frequencies between zero and half of the sampling frequency and combined with the proper signal information, which creates the artifact. Oversampling creates a larger field of view, more data needs to be stored and processed, but this is for modern MRI systems not a real problem. Oversampling in phase direction (no phase wrap), to eliminate wrap around artifacts, by increasing the number of phase encoding steps, results in longer scan/processing times.

(PE) The partial echo technique (also called fractional echo) is used to shorten the minimum echo time. By the acquisition of only a part of k-space data this technique benefits (like all partial Fourier techniques) from the complex conjugate symmetry between the k-space halves (this is called Hermitian symmetry).
The dephasing gradient in the frequency direction is reduced, and the duration of the readout gradient and the data acquisition window are shortened. Partial echo gives a better SNR at a given TE when a smaller FOV or thinner slices are selected, allows a longer sampling time, and a larger water fat shift (WFS, see also bandwidth) due to a lower gradient amplitude. The resolution is not affected. This is often used in gradient echo sequences (e.g. FLASH, Contrast Enhanced Magnetic Resonance Angiography) to reduce the echo time and yields a lower gradient moment. The disadvantage of using a partial echo can be a lower SNR, although this may be partly offset by the reduced echo time.
Also called Fractional Echo, Read Conjugate Symmetry, Single Side View.

See also Partial Fourier Technique and acronyms for 'partial echo' from different manufacturers.