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Inversion Recovery SequenceForum -
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Inversion Recovery Sequence Timing Diagram (IR) The inversion recovery pulse sequence produces signals, which represent the longitudinal magnetization existing after the application of a 180° radio frequency pulse that rotates the magnetization Mz into the negative plane. After an inversion time (TI - time between the starting 180° pulse and the following 90° pulse), a further 90° RF pulse tilts some or all of the z-magnetization into the xy-plane, where the signal is usually rephased with a 180° pulse as in the spin echo sequence. During the initial time period, various tissues relax with their intrinsic T1 relaxation time.
In the pulse sequence timing diagram, the basic inversion recovery sequence is illustrated. The 180° inversion pulse is attached prior to the 90° excitation pulse of a spin echo acquisition. See also the Pulse Sequence Timing Diagram. There you will find a description of the components.
The inversion recovery sequence has the advantage, that it can provide very strong contrast between tissues having different T1 relaxation times or to suppress tissues like fluid or fat. But the disadvantage is, that the additional inversion radio frequency RF pulse makes this sequence less time efficient than the other pulse sequences.

Contrast values:
PD weighted: TE: 10-20 ms, TR: 2000 ms, TI: 1800 ms
T1 weighted: TE: 10-20 ms, TR: 2000 ms, TI: 400-800 ms
T2 weighted: TE: 70 ms, TR: 2000 ms, TI: 400-800 ms

See also Inversion Recovery, Short T1 Inversion Recovery, Fluid Attenuation Inversion Recovery, and Acronyms for 'Inversion Recovery Sequence' from different manufacturers.
 
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 Brain MRI Inversion Recovery  Open this link in a new window
    
 Knee MRI Sagittal STIR 002  Open this link in a new window
 Brain MRI Coronal FLAIR 001  Open this link in a new window
    
 
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    • Pulse Sequence Timing Diagram
    • Double Inversion Recovery T1 Measurement
    • Knee MRI
    • Flow Sensitive Alternating Inversion Recovery
    • Pulse, 180°
 
Further Reading:
  Basics:
The equation for a repeated inversion recovery sequence
Contrast mechanisms in magnetic resonance imaging
2004   by www.iop.org    
  News & More:
FLAIR Vascular Hyperintensity: An Important MRI Marker in Patients with Transient Ischemic Attack
Thursday, 14 July 2022   by www.dovepress.com    
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Inversion RecoveryForum -
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(IR) Inversion recovery is an MRI technique, which can be incorporated into MR imaging, wherein the nuclear magnetization is inverted at a time on the order of T1 before the regular imaging pulse-gradient sequences. The resulting partial relaxation of the spins in the different structures being imaged can be used to produce an image that depends strongly on T1. This may bring out differences in the appearance of structures with different T1 relaxation times. Note that this does not directly produce an image of T1. T1 in a given region can be calculated from the change in the MR signal from the region due to the inversion pulse compared to the signal with no inversion pulse or an inversion pulse with a different inversion time. This sequence involves successive 180° and 90° pulses. The inversion recovery sequence is specified in terms of three parameters, inversion time (TI), repetition time (TR) and echo time (TE).

See also Inversion Recovery Sequence and FLAIR.
 
Images, Movies, Sliders:
 Brain MRI Inversion Recovery  Open this link in a new window
    
 Knee MRI Sagittal STIR 002  Open this link in a new window
    
 Brain MRI Coronal FLAIR 001  Open this link in a new window
 
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• View the DATABASE results for 'Inversion Recovery' (42).Open this link in a new window

 
Further Reading:
  Basics:
T1-weighted Phase Sensitive Inversion Recovery for Imaging Multiple Sclerosis Lesions in the Cervical Spinal Cord(.pdf)
   by www.healthcare.siemens.com    
Contrast mechanisms in magnetic resonance imaging
2004   by www.iop.org    
  News & More:
Artificial double inversion recovery images can substitute conventionally acquired images: an MRI-histology study
Wednesday, 16 February 2022   by www.nature.com    
Accurate T1 Quantification Using a Breath-hold Inversion Recovery TrueFISP Sequence
2003   by rsna2003.rsna.org    
MRI Resources 
MRI Physics - Services and Supplies - Cardiovascular Imaging - Research Labs - Movies - MRI Accidents
 
Multiplanar Inversion RecoveryInfoSheet: - Sequences - 
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(MPIR) An inversion recovery sequence with 3D acquisition.

See Inversion Recovery Sequence.
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Short T1 Inversion RecoveryInfoSheet: - Sequences - 
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(STIR) Also called Short Tau (t) (inversion time) Inversion Recovery. STIR is a fat suppression technique with an inversion time t = T1 ln2 where the signal of fat is zero (T1 is the spin lattice relaxation time of the component that should be suppressed). To distinguish two tissue components with this technique, the T1 values must be different. Fluid Attenuation Inversion Recovery (FLAIR) is a similar technique to suppress water.
Inversion recovery doubles the distance spins will recover, allowing more time for T1 differences. A 180° preparation pulse inverts the net magnetization to the negative longitudinal magnetization prior to the 90° excitation pulse. This specialized application of the inversion recovery sequence set the inversion time (t) of the sequence at 0.69 times the T1 of fat. The T1 of fat at 1.5 Tesla is approximately 250 with a null point of 170 ms while at 0.5 Tesla its 215 with a 148 ms null point. At the moment of excitation, about 120 to 170 ms after the 180° inversion pulse (depending of the magnetic field) the magnetization of the fat signal has just risen to zero from its original, negative, value and no fat signal is available to be flipped into the transverse plane.
When deciding on the optimal T1 time, factors to be considered include not only the main field strength, but also the tissue to be suppressed and the anatomy. In comparison to a conventional spin echo where tissues with a short T1 are bright due to faster recovery, fat signal is reversed or darkened. Because body fluids have both a long T1 and a long T2, it is evident that STIR offers the possibility of extremely sensitive detection of body fluid. This is of course, only true for stationary fluid such as edema, as the MRI signal of flowing fluids is governed by other factors.

See also Fat Suppression and Inversion Recovery Sequence.
 
Images, Movies, Sliders:
 Sagittal Knee MRI Images STIR  Open this link in a new window
      

 
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• View the DATABASE results for 'Short T1 Inversion Recovery' (3).Open this link in a new window

 
Further Reading:
  Basics:
Can Short Tau Inversion Recovery (STIR) Imaging Be Used as a Stand-Alone Sequence To Assess a Perianal Fistulous Tract on MRI? A Retrospective Cohort Study Comparing STIR and T1-Post Contrast Imaging
Wednesday, 17 January 2024   by www.cureus.com    
  News & More:
Generating Virtual Short Tau Inversion Recovery (STIR) Images from T1- and T2-Weighted Images Using a Conditional Generative Adversarial Network in Spine Imaging
Wednesday, 25 August 2021
Short tau inversion recovery (STIR) after intravenous contrast agent administration obscures bone marrow edema-like signal on forefoot MRI
Tuesday, 13 July 2021   by www.springermedizin.de    
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MRCP - MRA - Coils - NMR - Patient Information - Safety Products
 
Echo TimeForum -
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(TE) The echo time represents the time in milliseconds between the application of the 90° pulse and the peak of the echo signal in spin echo and inversion recovery pulse sequences.

See also Repetition Time, Spin Echo Sequence and Inversion Recovery Sequence.
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• View the DATABASE results for 'Echo Time' (36).Open this link in a new window

 
Further Reading:
  Basics:
Magnetic resonance imaging
   by www.scholarpedia.org    
  News & More:
Kidney stone imaging with 3D ultra-short echo time (UTE) magnetic resonance imaging. A phantom study - Abstract
Wednesday, 11 March 2015   by www.urotoday.com    
Ultrashort echo time (UTE) MRI of the spine in thalassaemia
February 2004   by bjr.birjournals.org    
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