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MEDIC TechniqueInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
Multiple echoes acquired in a gradient echo scan are combined into an image, for less artifacts and higher SNR; the early echoes provide increased SNR, whilst later echoes boost contrast. This sequence type is also known as MERGE (Multiple Echo Recombined Gradient Echo)

See also Multi Echo Data Image Combination, Bipolar Gradient Pulse.
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Further Reading:
  Basics:
Cutting Edge Imaging of THE Spine
February 2007   by www.pubmedcentral.nih.gov    
MRI Resources 
Portals - Fluorescence - MR Guided Interventions - Brain MRI - Artifacts - Developers
 
MAGNETOM Prisma
 
www.healthcare.siemens.com/magnetic-resonance-imaging/3t-mri-scanner/magnetom-prisma From Siemens Medical Systems; Received FDA clearance in 2013.
The MAGNETOM Prisma is the 3T PowerPack for exploration that offers most demanding clinical and research challenges of today and the future. The latest parallel transmit technology, TimTX TrueShape, enables zooming into specific body regions for enhanced image quality. Furthermore, the Tim 4G integrated coil technology offers remarkable imaging flexibility and supports complex examinations across the whole body.
Onsite upgrades to the MAGNETOM Prisma for customers who have already installed the 3 Tesla MAGNETOM Trio are possible.
Device Information and Specification
CLINICAL APPLICATION
Whole Body
CONFIGURATION
Ultra-short bore
3 Tesla
Head, spine, torso/ body coil, neurovascular, cardiac, neck, shoulder, knee, wrist, foot//ankle and multi-purpose flex coils. Peripheral vascular, breast, shoulder.
CHANNELS (min. / max. configuration)
64, 128
IMAGING TECHNIQUES
iPAT, mSENSE and GRAPPA (image, k-space), noncontrast angiography, radial motion compensation, Dixon
FOV
0.5 - 50 cm
BORE DIAMETER
or W x H
At isocenter: L-R 60 cm
TABLE CAPACITY
250 kg
MAGNET WEIGHT (gantry included)
13000 kg
DIMENSION H*W*D (gantry included)
173 x 230 x 222 cm
5-GAUSS FRINGE FIELD
2.6 m / 4.6 m
CRYOGEN USE
Zero boil off rate, refill approx. 10 years
COOLING SYSTEM
Water
up to 200 T/m/s
MAX. AMPLITUDE
80 mT/m
Passive, active; first order, second order
POWER REQUIREMENTS
380 / 400 / 420 / 440 / 460 / 480 V, 3-phase + ground;
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MRI Resources 
MRI Technician and Technologist Career - Open Directory Project - PACS - Libraries - Resources - Shielding
 
EPIX Pharmaceuticals, Inc.MRI Resource Directory:
 - Developers -
 
www.epixmed.com [This entry is marked for removal.]

(July 20, 2009 - EPIX Pharmaceuticals, Inc. announced today that, in light of the company's lack of capital and inability to obtain additional financing or consummate a strategic transaction, it has entered into an Assignment for the Benefit of Creditors, effective immediately, in accordance with Massachusetts law).
EPIX has been a specialty pharmaceutical firm developing targeted contrast agents to improve the capability of MRI as a diagnostic tool for a variety of diseases. Gadofosveset trisodium (formerly MS-325, Vasovist™, now ABLAVARt™), is an injectable intravascular contrast agents designed for multiple vascular imaging applications, including peripheral vascular disease and coronary artery disease. EPIX conducted a pivotal Phase III trial for the detection of peripheral vascular disease, as well as a Phase II feasibility trial for coronary artery disease diagnosis.
To ensure rapid development and adoption of gadofosveset trisodium into clinical practice upon regulatory approval, EPIX pursued an aggressive product development plan and commercialization strategy. The Company established an exclusive, worldwide sales and marketing agreement with Bayer Schering Pharma AG. EPIX also established corporate collaborations with GE Healthcare, Philips Medical Systems and Siemens Medical Systems, the three leading MRI manufacturers, which together account for approximately 80 percent of the MRI machines installed worldwide.
EPIX had other MRI contrast agents under development, most significantly a novel prototype blood clot agent (EP-2104R). Potential clinical applications for this type of agent include detection of deep venous thrombosis, pulmonary embolism and blood clots in the coronary and carotid arteries. Currently, there is no high resolution imaging technique to directly visualize blood clots in patients with suspected cardiovascular disease.
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Further Reading:
  Basics:
Epix Pharmaceuticals to shut down
Tuesday, 21 July 2009   by boston.bizjournals.com    
Searchterm 'MEDIC Technique' was also found in the following services: 
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MRI History
 
Sir Joseph Larmor (1857-1942) developed the equation that the angular frequency of precession of the nuclear spins being proportional to the strength of the magnetic field. [Larmor relationship]
In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
In 1975, Richard Ernst introduced 2D NMR using phase and frequency encoding, and the Fourier Transform. Instead of Paul Lauterbur's back-projection, he timely switched magnetic field gradients ('NMR Fourier Zeugmatography'). [This basic reconstruction method is the basis of current MRI techniques.]
1977/78: First images could be presented. A cross section through a finger by Peter Mansfield and Andrew A. Maudsley. Peter Mansfield also could present the first image through the abdomen.
In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
In 1984, FONAR Corporation receives FDA approval for its first MRI scanner.
1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH (fast low angle shot) sequence.
1988: Schering's MAGNEVIST gets its first approval by the FDA.
In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
 
Images, Movies, Sliders:
 Cardiac Infarct Short Axis Cine Overview  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 
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Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
Fonar Our History
   by www.fonar.com    
  News & More:
Scientists win Nobels for work on MRI
Tuesday, 10 June 2003   by usatoday30.usatoday.com    
2001 Lemelson-MIT Lifetime Achievement Award Winner
   by web.mit.edu    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
MRI Resources 
Implant and Prosthesis - Most Wanted - Jobs - Resources - Hospitals - Process Analysis
 
Signa Infinity 1.5T™ with ExciteInfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.MRI Resource Directory:
 - Devices -
 
www.gehealthcare.com/usen/mr/s_excite15/index.html From GE Healthcare;
'EXCITE technology has the potential to open the door to new imaging techniques and clinical applications, leaping beyond conventional two and three-dimensional MRI to true 4D imaging that will improve the diagnosis of disease throughout the human body from head to foot.' Robert R. Edelman, M.D., Professor of Radiology at Northwestern University Medical School and Chairman, Department of Radiology, at Evanston Northwestern Healthcare.
Device Information and Specification
CLINICAL APPLICATION
Whole body
CONFIGURATION
Short bore
Head and body coil standard; all other coils optional; open architecture makes system compatible with a wide selection of coils
Optional 2D/3D brain and prostate
SYNCHRONIZATION
ECG/peripheral, respiratory gating, (SmartPrep, SmartStep)
PULSE SEQUENCES
Standard: SE, IR, 2D/3D GRE and SPGR, Angiography: 2D/3D TOF, 2D/3D Phase Contrast;; 2D/3D FSE, 2D/3D FGRE and FSPGR, SSFP, FLAIR, EPI, optional: 2D/3D Fiesta, FGRET, Spiral, Tensor
IMAGING MODES
Localizer, single slice, multislice, volume, fast, POMP, multi slab, cine
TR
1.3 to 12000 msec in increments of 1 msec
TE
0.4 to 2000 msec in increments of 1 msec
SINGLE/MULTI SLICE
Simultaneous scan and reconstruction;; up to 200 or 400 images per second
1 cm to 48 cm continuous
2D 0.7 mm to 20 mm; 3D 0.1 mm to 5 mm
1028 x 1024
MEASURING MATRIX
128x512 steps 32 phase encode
PIXEL INTENSITY
256 gray levels
0.08 mm; 0.02 mm optional
MAGNET WEIGHT
3863 kg
H*W*D
172 x 208 x 216 cm
POWER REQUIREMENTS
480 or 380/415
COOLING SYSTEM TYPE
Closed-loop water-cooled gradient
CRYOGEN USE, L/hr
less than 0.03 L/hr liquid helium
STRENGTH
SmartSpeed 23 mT/m, HiSpeed Plus 33 mT/m, EchoSpeed Plus 33 mT/m
5-GAUSS FRINGE FIELD
4.0 m x 2.8 m axial x radial
Active
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MRI Resources 
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