An effect of chemical shift is that of spatial misregistration. Because the frequency displacement caused by chemical shift cannot be differentiated from intended spatial frequency encoding misregistration of the resultant signal may occur along the frequency-encoding direction. This artifact can be seen in a FFE or SE sequence as a bright or dark band at the edge of the anatomy.

See Chemical Shift Artifact.

Magnetic resonance imaging (MRI) of the spine is a noninvasive procedure to evaluate different types of tissue, including the spinal cord, vertebral disks and spaces between the vertebrae through which the nerves travel, as well as distinguish healthy tissue from diseased tissue.
The cervical, thoracic and lumbar spine MRI should be scanned in individual sections. The scan protocol parameter like e.g. the field of view (FOV), slice thickness and matrix are usually different for cervical, thoracic and lumbar spine MRI, but the method is similar. The standard views in the basic spinal MRI scan to create detailed slices (cross sections) are sagittal T1 weighted and T2 weighted images over the whole body part, and transverse (e.g. multi angle oblique) over the region of interest with different pulse sequences according to the result of the sagittal slices. Additional views or different types of pulse sequences like fat suppression, fluid attenuation inversion recovery (FLAIR) or diffusion weighted imaging are created dependent on the indication.

Indications:

Contrast enhanced MRI techniques delineate infections vs. malignancies, show a syrinx cavity and support to differentiate the postoperative conditions. After surgery for disk disease, significant fibrosis can occur in the spine. This scarring can mimic residual disk herniation. Magnetic resonance myelography evaluates spinal stenosis and various intervertebral discs can be imaged with multi angle oblique techniques. Cine series can be used to show true range of motion studies of parts of the spine. Advanced open MRI devices are developed to perform positional scans in the position of pain or symptom (e.g. Uprightâ„¢ MRI formerly Stand-Up MRI).

Short name: P792, generic name: Gadomeritol
A macromolecular Gd-DOTA derivate under development (phase II, Guerbet SA) as a positive enhancing blood pool agent (MRI contrast agent) for, e.g. myocard perfusion and tumor characterization.

See also Blood Pool Agents.