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Spin Density
 
(N) The SI units is moles/m3.
Definition: The concentration of nuclei in tissue processing at the Larmor frequency in a given region; one of the principal determinants of the strength of the NMR signal from the region.
For water, there are about 1.1 x 105 moles of hydrogen per m3, or 0.11 moles of hydrogen/cm3.
The signal intensity measured is related to the square of the xy-magnetization, which in a SE pulse sequence is given by
Mxy = Mxy0(1-exp(-TR/T1)) exp(-TE/T2)
where Mxy0 = Mz0 is proportional to the proton or spin density, and corresponds to the z-magnetization present at zero time of the experiment when it is tilted into the xy-plane.
True spin density is not imaged directly, but must be calculated from signals received with different interpulse times. The spin density contrast can be generated by using a long TR and sampling the data immediately after the RF pulse (with a TE as short as possible).
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Further Reading:
  Basics:
Magnetic resonance imaging
   by www.scholarpedia.org    
How Many? A Dictionary of Units of Measurement © Russ Rowlett and the University of North Carolina at Chapel Hill
Wednesday, 21 March 2001   by www.unc.edu    
How does the proton get its spin?
Wednesday, 17 February 2010   by www.physorg.com    
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Spin Echo SequenceInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.MRI Resource Directory:
 - Sequences -
 
Spin Echo Timing Diagram (SE) The most common pulse sequence used in MR imaging is based of the detection of a spin or Hahn echo. It uses 90° radio frequency pulses to excite the magnetization and one or more 180° pulses to refocus the spins to generate signal echoes named spin echoes (SE).
In the pulse sequence timing diagram, the simplest form of a spin echo sequence is illustrated.
The 90° excitation pulse rotates the longitudinal magnetization (Mz) into the xy-plane and the dephasing of the transverse magnetization (Mxy) starts.
The following application of a 180° refocusing pulse (rotates the magnetization in the x-plane) generates signal echoes. The purpose of the 180° pulse is to rephase the spins, causing them to regain coherence and thereby to recover transverse magnetization, producing a spin echo.
The recovery of the z-magnetization occurs with the T1 relaxation time and typically at a much slower rate than the T2-decay, because in general T1 is greater than T2 for living tissues and is in the range of 100-2000 ms.
The SE pulse sequence was devised in the early days of NMR days by Carr and Purcell and exists now in many forms: the multi echo pulse sequence using single or multislice acquisition, the fast spin echo (FSE/TSE) pulse sequence, echo planar imaging (EPI) pulse sequence and the gradient and spin echo (GRASE) pulse sequence;; all are basically spin echo sequences.
In the simplest form of SE imaging, the pulse sequence has to be repeated as many times as the image has lines.
Contrast values:
PD weighted: Short TE (20 ms) and long TR.
T1 weighted: Short TE (10-20 ms) and short TR (300-600 ms)
T2 weighted: Long TE (greater than 60 ms) and long TR (greater than 1600 ms)
With spin echo imaging no T2* occurs, caused by the 180° refocusing pulse. For this reason, spin echo sequences are more robust against e.g., susceptibility artifacts than gradient echo sequences.

See also Pulse Sequence Timing Diagram to find a description of the components.
 
Images, Movies, Sliders:
 Shoulder Coronal T1 SE  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 Shoulder Axial T1 SE  Open this link in a new window
 MRI Orbita T1  Open this link in a new window
    
 
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• View the DATABASE results for 'Spin Echo Sequence' (24).Open this link in a new window

 
Further Reading:
  Basics:
Fast Spin Echo(.pdf)
Tuesday, 24 January 2006   by www.81bones.net    
Magnetic resonance imaging
   by www.scholarpedia.org    
FUNDAMENTALS OF MRI: Part I
   by www.e-radiography.net    
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New MR sequence helps radiologists more accurately evaluate abnormalities of the uterus and ovaries
Thursday, 23 April 2009   by www.eurekalert.org    
MRI techniques improve pulmonary embolism detection
Monday, 19 March 2012   by medicalxpress.com    
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