(ISIS) Image selected in vivo spectroscopy is used as a localization sequence to provide complete gradient controlled three-dimensional localization with a reduced number of sequence cycles, e.g. for in vivo 31P spectroscopy. The ISIS method generates three 180° pulses prior to a 90° pulse, after which the free induction decay is recorded. Specific 180° pulses (slice-selective) are combined and the FID's added or subtracted to generate a spectrum.
An advantage of the ISIS method is that the magnetization (before the final 90° pulse) is predominantly along the z-axis and so T2 effects are relatively small. This explains the value of this technique for 31P data acquisition, because some phosphorus metabolites (e.g. ATP) have short T2 values.
A disadvantage is that eight acquisitions are required to accomplish the spatial localization, therefore the sequence cannot be used for localized shimming. Another problem, because any variation between these data collections (for example, due to movement) will degrade these applications, can be solved by incorporating outer volume suppression techniques such as OSIRIS (modified ISIS).

(SCT) The total scan time is the time required to collect all data needed to generate the programmed images. The scan time is related to the used pulse sequence and dependent on the assemble of parameters like e.g., repetition time (TR), Matrix, number of signal averages (NSA), TSE- or EPI factor and flip angle.
For example, the total scan time for a standard spin echo or gradient echo sequence is number of repetitions x the scan time per repetition (means the product of repetition time (TR), number of phase encoding steps, and NSA).

See also Number of Excitations, Turbo Spin Echo Turbo Factor, Echo Planar Imaging Factor, Flip Angle and Image Acquisition Time.

See also acronyms for 'scan time parameters' from different manufacturers.

(SENSE) A MRI technique for relevant scan time reduction. The spatial information related to the coils of a receiver array are utilized for reducing conventional Fourier encoding. In principle, SENSE can be applied to any imaging sequence and k-space trajectories. However, it is particularly feasible for Cartesian sampling schemes. In 2D Fourier imaging with common Cartesian sampling of k-space sensitivity encoding by means of a receiver array enables to reduce the number of Fourier encoding steps.
SENSE reconstruction without artifacts relies on accurate knowledge of the individual coil sensitivities. For sensitivity assessment, low-resolution, fully Fourier-encoded reference images are required, obtained with each array element and with a body coil.
The major negative point of parallel imaging techniques is that they diminish SNR in proportion to the numbers of reduction factors. R is the factor by which the number of k-space samples is reduced. In standard Fourier imaging reducing the sampling density results in the reduction of the FOV, causing aliasing. In fact, SENSE reconstruction in the Cartesian case is efficiently performed by first creating one such aliased image for each array element using discrete Fourier transformation (DFT).
The next step then is to create a full-FOV image from the set of intermediate images. To achieve this one must undo the signal superposition underlying the fold-over effect. That is, for each pixel in the reduced FOV the signal contributions from a number of positions in the full FOV need to be separated. These positions form a Cartesian grid corresponding to the size of the reduced FOV.
The advantages are especially true for contrast-enhanced MR imaging such as dynamic liver MRI (liver imaging) , 3 dimensional magnetic resonance angiography (3D MRA), and magnetic resonance cholangiopancreaticography (MRCP).
The excellent scan speed of SENSE allows for acquisition of two separate sets of hepatic MR images within the time regarded as the hepatic arterial-phase (double arterial-phase technique) as well as that of multidetector CT.
SENSE can also increase the time efficiency of spatial signal encoding in 3D MRA. With SENSE, even ultrafast (sub second) 4D MRA can be realized.
For MRCP acquisition, high-resolution 3D MRCP images can be constantly provided by SENSE. This is because SENSE resolves the presence of the severe motion artifacts due to longer acquisition time. Longer acquisition time, which results in diminishing image quality, is the greatest problem for 3D MRCP imaging.
In addition, SENSE reduces the train of gradient echoes in combination with a faster k-space traversal per unit time, thereby dramatically improving the image quality of single shot echo planar imaging (i.e. T2 weighted, diffusion weighted imaging).

(SMASH) Several lines of data are acquired for each phase encoding step, which is also referred to as a k-space trajectory.
SMASH imaging with a four-element array coil is four times faster and can be used to achieve almost real-time imaging. The maximum reduction in acquisition time is determined by the number of array coil elements. Thus, the heart can be scanned with higher temporal resolution and increased spatial resolution.
SMASH and SENSE differ from other techniques in which only one line of k-space data is acquired for each phase encoding gradient step.

See Sensitivity encoding.

A description of the factors used in creating an image should include the type and times of the pulse sequence, the number of signals averaged or added (NSA), the size of the reconstructed region, the size of the acquisition matrix in each direction, field of view and the slice thickness; usually printed at the border of MRI pictures.