(ASL) A MR image can be sensitized to the effect of inflowing blood spins if those spins are in a different magnetic state to that of the static tissue. Techniques known as ASL techniques uses this idea by magnetically labeling blood flowing into the slices of interest. Contrast agents are not required for these techniques. This perfusion measurement is completely noninvasive.
Blood flowing into the imaging slice exchanges with tissue water, altering the tissue magnetization. A perfusion-weighted image can be generated by the subtraction of an image in which inflowing spins have been labeled from an image in which spin labeling has not been performed. Quantitative perfusion maps can be calculated if other parameters (such as tissue T1 and the efficiency of spin labeling) also are measured.

(fMRI) Functional magnetic resonance imaging is a technique used to determine the dynamic brain function, often based on echo planar imaging, but can also be performed by using contrast agents and observing their first pass effects through brain tissue. Functional magnetic resonance imaging allows insights in a dysfunctional brain as well as into the basic workings of the brain.
The in functional brain MRI most frequently used effect to assess brain function is the blood oxygenation level dependent contrast (BOLD) effect, in which differential changes in brain perfusion and their resultant effect on the regional distribution of oxy- to deoxyhaemoglobin are observable because of the different 'intrinsic contrast media' effects of the two haemoglobin forms. Increased brain activity causes an increased demand for oxygen, and the vascular system actually overcompensates for this, increasing the amount of oxygenated haemoglobin. Because deoxygenated haemoglobin attenuates the MR signal, the vascular response leads to a signal increase that is related to the neural activity.
Functional imaging relates body function or thought to specific locations where the neural activity is taking place. The brain is scanned at low resolution but at a fast rate (typically once every 2-3 seconds). Structural MRI together with fMRI provides an anatomical baseline and best spatial resolution.
Interactions can also be seen from the motor cortex to the cerebellum or basal ganglia in the case of a movement disorder such as ataxia. For example: by a finger movement the briefly increase in the blood circulation of the appropriate part of the brain controlling that movement, can be measured.

(IVIM) Spins moving in fluids with different velocities and possibly in different directions. This is being found to a small degree in all tissues as a result of capillary perfusion or diffusion. Important velocity changes occur as one moves from the vessel wall towards the center of the vessel. Hence, spins (to a variable degree) have different velocities within a single imaging voxel.
This effect can be measured using special pulse sequences such as in diffusion imaging or diffusion weighed imaging. When the velocity differences are marked, as occurs in larger blood vessels, effects due to IVIM are visible in standard MR images and give rise to flow related dephasing. The effects are more visible when longer echo times are used.

(LITT) Laser induced thermo therapy is a therapeutically destruction of tumor or metastasis tissue with a thermolaser. Malignant tissue reacts very sensitive to heat. The heating of the malignant tissue results in a degeneration or coagulation and the death of the malignant cells by temperatures from 45 °C to 99 °C.
Induced thermal damage can be variable and unpredictable due to thermally induced changes in tissue thermal and blood perfusion. The affection can be controlled by thermo sensitive MRI sequences. The temperature can be monitored during the procedure and MR imaging following the procedure shows how effectively the tumor is damaged.