This sequence type is a TSE counterpart to double echo sequences. To keep the echo train as short as possible, only echoes for PD and T2 weighted images, where the phase encoding gradient has a small amplitude, are measured separately. The echoes that determine resolution are used in both raw data matrices. This reduces the number of echoes required. Also the SAR drops and more slices can be acquired in the same repetition time.

(DE FGRE, Dual/FFE, DE FFE) Simultaneously acquired in and out of phase TE gradient echo images. To quantitatively measure the signal intensity differences between out of phase and in phase images the parameters should be the same except for the TE.
The chemical shift artifact appearing on the out-of-phase image allows for the detection of lipids in the liver or adrenal gland, such as diffuse fatty infiltration, focal fatty infiltration, focal fatty sparing, benign adrenocortical masses and intracellular lipids within a hepatocellar neoplasm, where spin echo and fat suppression techniques are not as sensitive. Specific pathologies that have been reported include liver lipoma, angiomyolipoma, myelolipoma, metastatic liposarcoma, teratocarcinoma, melanoma, haemorrhagic neoplasm and metastatic choriocarcinoma.

(FAIR) In this sequence 2 inversion recovery images are acquired, one with a nonselective and the other with a slice selective inversion pulse. The z-magnetization in the first sequence is independent of flow. Inflowing spins give z-magnetization from second pulse. A major signal loss in FAIR is the T1 relaxation of tagged blood in transit to the imaging slice. Sharper edges of the inversion pulse give narrow spacing between the inversion edge and the 1st slice because reduced transit time gives lower T1 relaxation induced signal loss. The difference of the images in a consequence contains information proportional to flow (blood partition coefficient). Standard adiabatic inversion RF pulse does not have good slice-profile, because of power/SAR limitation. A c-shaped frequency offset corrected inversion (FOCI) RF pulse can help to increase the signal.
Perfusion imaging, e.g. myocardial, using tissue water as endogenous contrast is suggested.

A problem occurs in the phase encoding direction, where the phases of signal-bearing tissues outside of the FOV in the y-direction are a replication of the phases that are encoded within the FOV. This signal will be mapped (wrapped, backfolded) back into the image at incorrect locations.
Foldover suppression (phase oversampling, no phase wrap) is a user-selectable parameter that maps this signal to its correct location outside the FOV, then discards any signal from outside the FOV before displaying the image. In order to be able to choose this parameter, in most cases more than an average is necessary.

See also Phase Wrapping Artifact and Oversampling.

Encoding the distribution of sources of MR signals along a direction in space with different frequencies. In general, it is necessary to acquire a set of signals with a suitable set of different frequencies in order to reconstruct the distribution of the sources along the encoded direction. In the absence of other position encoding, the Fourier transformation of the resulting signal is a one-dimensional projection profile of the object.