(FRE) Flow related enhancement could be seen most for blood flow, but also for other liquids with some MR imaging techniques, as an increase in intensity due to the washout of saturated spins. FRE provides positive contrast ("bright blood") of vascular details in time of flight MRA as well as the physiologic characterization of blood flow.
If stationary spins within the scanned region experience only an incomplete T1 relaxation between the repeated radio frequency (RF) excitations, this results in fewer signal of the stationary tissue (compared to inflowing blood with completely relaxed spins). The degree of the flow related enhancement is proportional to the blood flow velocity and the used repetition time. The use of flow compensation (gradient moment nulling) improves the FRE especially in gradient echo sequences.

(GE) An echo signal generated from a free induction decay by means of a bipolar switched magnetic gradient. The echo is produced by reversing the direction of a magnetic field gradient or by applying balanced pulses of magnetic field gradient before and after a refocusing RF pulse so as to cancel out the position dependent phase shifts that have accumulated due to the gradient.
In the latter case, the gradient echo is generally adjusted to be coincident with the RF spin echo. When the RF and gradient echoes are not coincident, the time of the gradient echo is denoted echo time (TE) and the difference in time between the echoes is denoted time difference (TD).
Gradient echo does not refocus the effects of main field inhomogeneity and therefore is generally used with a short echo time. Disadvantages of gradient echo imaging are compromised anatomic details and artifacts in regions with varying susceptibility e.g. between the air-containing sinuses and brain and especially between haemorrhages and normal tissue.

See also Susceptibility Artifact.

(Hb) Haemoglobin is the major endogenous oxygen-binding molecule, responsible for binding oxygen in the lung and transporting it to the tissues by means of the circulation. Haemoglobin is contained in very high concentration in the red blood cells.
Haemoglobin is an Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+ (ferrous iron). If an oxygen molecule is bound to Hb, Hb is called oxyhaemoglobin, if no oxygen molecule is bound it is called deoxyhaemoglobin. When haemoglobin is oxidized (i.e. in a haematoma), Fe2+ is transformed into Fe3+. The resulting haemoglobin is then called metoxyhaemoglobin (Hb Fe3+).
Deoxyhaemoglobin and metoxyhaemoglobin act as paramagnetic contrast agents in MR, while oxyhaemoglobin is diamagnetic. This partly explains the special appearance of an aging haematoma in MR imaging and is also the basic of the blood oxygenation level dependent contrast (BOLD) used in functional magnetic resonance imaging of the brain (fMRI).

(I MRA) In MR imaging, inflowing non-saturated fluid gives a higher signal intensity than stationary tissue. This effect makes it especially useful for imaging of flowing blood. Other factors such as susceptibility and spin saturation, can affect the signal of the blood within the vessels. Furthermore turbulence is part of normal blood flow and can decrease signal intensity.

See also Time of Flight Angiography.

(IVIM) Spins moving in fluids with different velocities and possibly in different directions. This is being found to a small degree in all tissues as a result of capillary perfusion or diffusion. Important velocity changes occur as one moves from the vessel wall towards the center of the vessel. Hence, spins (to a variable degree) have different velocities within a single imaging voxel.
This effect can be measured using special pulse sequences such as in diffusion imaging or diffusion weighed imaging. When the velocity differences are marked, as occurs in larger blood vessels, effects due to IVIM are visible in standard MR images and give rise to flow related dephasing. The effects are more visible when longer echo times are used.