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Result : Searchterm 'fmri' found in 0 term [] and 11 definitions []
| previous 6 - 10 (of 11) nextResult Pages : [1 2 3] | | | | Searchterm 'fmri' was also found in the following services: | | | | |
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(Hb) Haemoglobin is the major endogenous oxygen-binding molecule, responsible for binding oxygen in the lung and transporting it to the tissues by means of the circulation. Haemoglobin is contained in very high concentration in the red blood cells.
Haemoglobin is an Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+ (ferrous iron).
If an oxygen molecule is bound to Hb, Hb is called oxyhaemoglobin, if no oxygen molecule is bound it is called deoxyhaemoglobin.
When haemoglobin is oxidized (i.e. in a haematoma), Fe2+ is transformed into Fe3+.
The resulting haemoglobin is then called metoxyhaemoglobin (Hb Fe3+). Deoxyhaemoglobin and metoxyhaemoglobin act as paramagnetic contrast agents in MR, while oxyhaemoglobin is diamagnetic. This partly explains the special appearance of an aging haematoma in MR imaging and is also the basic of the blood oxygenation level dependent contrast ( BOLD) used in functional magnetic resonance imaging of the brain ( fMRI). | | | | | Further Reading: | | Basics:
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The principal advantage of MRI at high field is the increase in signal to noise ratio. This can be used to improve anatomic and/or temporal resolution and reduce scan time while preserving image quality. MRI devices for whole body imaging for human use are available up to 3 tesla (3T). Functional MRI ( fMRI) and MR spectroscopy ( MRS) benefit significantly. In addition, 3T machines have a great utility in applications such as TOF MRA and DTI. Higher field strengths are used for imaging of small parts of the body or scientific animal experiments. Higher contrast may permit reduction of gadolinium doses and, in some cases, earlier detection of disease.
Using high field MRI//MRS, the RF-wavelength and the dimension of the human body complicating the development of MR coils. The absorption of RF power causes heating of the tissue. The energy deposited in the patient's tissues is fourfold higher at 3T than at 1.5T. The specific absorption rate (SAR) induced temperature changes of the human body are the most important safety issue of high field MRI//MRS.
Susceptibility and chemical shift dispersion increase like T1, therefore high field MRI occasionally exhibits imaging artifacts. Most are obvious and easily recognized but some are subtle and mimic diseases. A thorough understanding of these artifacts is important to avoid potential pitfalls. Some imaging techniques or procedures can be utilized to remove or identify artifacts. See also Diffusion Tensor Imaging.
See also the related poll result: ' In 2010 your scanner will probably work with a field strength of' | | | | | | • View the DATABASE results for 'High Field MRI' (16).
| | | • View the NEWS results for 'High Field MRI' (9).
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From Siemens Medical Systems;
The MAGNETOM 7T is designed as an open research platform. 7T MRI provides anatomical detail at the submillimiter scale, enhanced contrast mechanisms, outstanding spectroscopy performance, ultra-high resolution functional imaging ( fMRI), multinuclear whole-body MRI and functional information.
This ultra high field (UHF) MRI device is a research system and not cleared, approved or licensed in any jurisdiction for patient examinations.
Device Information and Specification
CLINICAL APPLICATION
Whole body
High-performance, ultra high field coils available. Integration and support for coil developments.
CHANNELS (min. / max. configuration)
32, optional 8 channels TX array
40 x 40 x 30 cm³ less than 8% nonlinearity
MAGNET WEIGHT (gantry included)
35017 kg
DIMENSION H*W*D (gantry included)
320 x 240 x 317,5 cm
MAX. AMPLITUDE
up to 70 mT/m
Up to 3rd order shim coils, user configurable B0 shim ? B0 maps and ROI definition
POWER REQUIREMENTS
2000 Volts, 650A
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From Siemens Medical Systems;
the 3 T MAGNETOM Allegra is a dedicated MR headscanner, perfect as a research system in cognitive and neuroscience with MRS and fMRI. MAGNETOM Allegra is a full member of the MAGNETOM product family. It uses many common components, i.e. electronics, computer system, software and pulse sequence concepts.
Device Information and Specification
GRE, IR, FIR, STIR, TrueIR/FISP, FSE, FLAIR, MT, SS-FSE, MT-SE, MTC, MSE, EPI, GMR, fat/water sat./exc.
IMAGING MODES
Single, multislice, volume study, multi angle, multi oblique
178 images/sec at 256 x 256 at 100% FOV
1024 x 1024 full screen display
MAGNET WEIGHT (gantry included)
5500 kg
DIMENSION H*W*D (gantry included)
220 x 220 x 147 cm
POWER REQUIREMENTS
380/400/420/440/480 V
Passive, act.; 1st order std./2nd opt.
| | | | • View the DATABASE results for 'MAGNETOM Allegra™' (2).
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In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
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Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
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In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
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In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
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1977/78: First images could be presented.
A cross section through a finger by Peter Mansfield and Andrew A. Maudsley.
Peter Mansfield also could present the first image through the abdomen.
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In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
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1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
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1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
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In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
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1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH ( fast low angle shot) sequence.
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1988: Schering's MAGNEVIST gets its first approval by the FDA.
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In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
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From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
| | | | | | • View the DATABASE results for 'MRI History' (6).
| | | • View the NEWS results for 'MRI History' (1).
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