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ContrastForum -
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Contrast is the relative difference of signal intensities in two adjacent regions of an image.
Due to the T1 and T2 relaxation properties in magnetic resonance imaging, differentiation between various tissues in the body is possible. Tissue contrast is affected by not only the T1 and T2 values of specific tissues, but also the differences in the magnetic field strength, temperature changes, and many other factors. Good tissue contrast relies on optimal selection of appropriate pulse sequences (spin echo, inversion recovery, gradient echo, turbo sequences and slice profile).
Important pulse sequence parameters are TR (repetition time), TE (time to echo or echo time), TI (time for inversion or inversion time) and flip angle. They are associated with such parameters as proton density and T1 or T2 relaxation times. The values of these parameters are influenced differently by different tissues and by healthy and diseased sections of the same tissue.
For the T1 weighting it is important to select a correct TR or TI. T2 weighted images depend on a correct choice of the TE. Tissues vary in their T1 and T2 times, which are manipulated in MRI by selection of TR, TI, and TE, respectively. Flip angles mainly affect the strength of the signal measured, but also affect the TR/TI/TE parameters.
Conditions necessary to produce different weighted images:
T1 Weighted Image: TR value equal or less than the tissue specific T1 time - TE value less than the tissue specific T2 time.
T2 Weighted Image: TR value much greater than the tissue specific T1 time - TE value greater or equal than the tissue specific T2 time.
Proton Density Weighted Image: TR value much greater than the tissue specific T1 time - TE value less than the tissue specific T2 time.

See also Image Contrast Characteristics, Contrast Reversal, Contrast Resolution, and Contrast to Noise Ratio.
 
Images, Movies, Sliders:
 Fetus (Brain) and Dermoid in Mother  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
SlidersSliders Overview

 Anatomic MRI of the Knee 1  Open this link in a new window
    
SlidersSliders Overview

 Anatomic Imaging of the Liver  Open this link in a new window
      

 Brain MRI Inversion Recovery  Open this link in a new window
    
 
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• Related Searches:
    • Inversion Time
    • Breast MRI
    • Contrast Agents
    • Contrast to Noise Ratio
    • Repetition Time
 
Further Reading:
  Basics:
Magnetic resonance imaging
   by www.scholarpedia.org    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
Image Characteristics and Quality
   by www.sprawls.org    
  News & More:
A natural boost for MRI scans
Monday, 21 October 2013   by www.eurekalert.org    
A groundbreaking new graphene-based MRI contrast agent
Friday, 8 June 2012   by www.nanowerk.com    
New MRI Chemical Offers Amazing Contrast
Friday, 22 January 2010   by news.softpedia.com    
MRI Resources 
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Magnetic ForcesMRI Resource Directory:
 - MRI Accidents -
 
Forces can result from the interaction of magnetic fields. Pulsed magnetic field gradients can interact with the main magnetic field during the MRI scan, to produce acoustic noise through the gradient coil.
Magnetic fields attract ferromagnetic objects with forces, which can be a lethal danger if one is hit by an unrestrained object in flight. One could also be trapped between the magnet and a large unrestrained ferromagnetic object or the object could damage the MRI machine.
Access control and personnel awareness are the best preventions of such accidents. The attraction mechanism for ferromagnetic objects is that the magnetic field magnetizes the iron. This induced magnetization reacts with the gradient of the magnetic field to produce an attraction toward the strongest area of the field. The details of this interaction are very dependent on the shape and composition of the attracted object. There is a very rapid increase of force as one approaches a magnet. There is also a torque or twisting force on objects, e.g. a long cylinder (such as a pen or an intracranial aneurysm clip) will tend to align along the magnet's field lines. The torque increases with field strength while the attraction increases with field gradient.
Depending on the magnetic saturation of the object, attraction is roughly proportional to object mass. Motion of conducting objects in magnetic fields can induce eddy currents that can have the effect of opposing the motion.

See also Duty Cycle.

See also the related poll result: 'Most outages of your scanning system are caused by failure of'
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Further Reading:
  Basics:
How strong are magnets?
   by my.execpc.com    
Magnetic Field of the Strongest Magnet
2003   by hypertextbook.com    
  News & More:
Imaging chain faces regulators after inmate, guard get stuck to MRI machine
Friday, 1 December 2023   by healthimaging.com    
Measuring magnetic force field distributions in microfluidic devices: Experimental and numerical approaches
Saturday, 2 December 2023   by analyticalsciencejournals.onlinelibrary.wiley.com    
Two stuck to MRI machine for 4 hrs
Tuesday, 11 November 2014   by www.mumbaimirror.com    
New imaging project for new applications in cancer diagnostics
Monday, 27 March 2017   by www.news-medical.net    
MRI Resources 
MRI Accidents - Resources - Cochlear Implant - Guidance - Mobile MRI Rental - Implant and Prosthesis
 
Gradient Amplifier
 
In MRI systems, the gradient amplifier increases the energy of the signal before it reaches the gradient coils, in a way, that the field strength is intense enough to produce the variations in the main magnetic field for localization of the later received signal. Three gradient coils normally require three gradient amplifiers. As all amplifiers, gradient amplifiers produce heat, which requires cooling.

See also the related poll result: 'Most outages of your scanning system are caused by failure of'
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Knee MRI
 
Knee MRI, with its high soft tissue contrast is one of the main imaging tools to depict knee joint pathology. MRI allows accurate imaging of intra-articular structures such as ligaments, cartilage, menisci, bone marrow, synovium, and adjacent soft tissue.
Knee exams require a dedicated extremity coil, providing a homogenous imaging volume and high SNR to ensure best signal coverage. A complete knee MR examination includes for example sagittal and coronal T1 weighted, and proton density weighted pulse sequences +/- fat saturation, or STIR sequences. For high spatial resolution, maximal 4 mm thick slices with at least an in plane resolution of 0.75 mm and small gap are recommended. To depict the anterior cruciate ligament clearly, the sagittal plane has to be rotated 10 - 20° externally (parallel to the medial border of the femoral condyle). Retropatellar cartilage can bee seen for example in axial T2 weighted gradient echo sequences with Fatsat. However, the choice of the pulse sequences is depended of the diagnostic question, the used scanner, and preference of the operator.
Diagnostic quality in knee imaging is possible with field strengths ranging from 0.2 to 3T. With low field strengths more signal averages must be measured, resulting in increased scan times to provide equivalent quality as high field strengths.
More diagnostic information of meniscal tears and chondral defects can be obtained by direct magnetic resonance arthrography, which is done by introducing a dilute solution of gadolinium in saline (1:1000) into the joint capsule. The knee is then scanned in all three planes using T1W sequences with fat suppression. For indirect arthrography, the contrast is given i.v. and similar scans are started 20 min. after injection and exercise of the knee.
Frequent indications of MRI scans in musculoskeletal knee diseases are:
e.g., meniscal degeneration and tears, ligament injuries, osteochondral fractures, osteochondritis dissecans, avascular bone necrosis and rheumatoid arthritis.

See also Imaging of the Extremities and STIR.
 
Images, Movies, Sliders:
 Sagittal Knee MRI Images T1 Weighted  Open this link in a new window
      

 Anatomic MRI of the Knee 2  Open this link in a new window
    
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 Knee MRI Coronal Pd Spir 001  Open this link in a new window
 Sagittal Knee MRI Images STIR  Open this link in a new window
      

 Axial Knee MRI Images T2 Weighted  Open this link in a new window
 Anatomic MRI of the Knee 1  Open this link in a new window
    
SlidersSliders Overview

 
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Further Reading:
  Basics:
Musculoskeletal MRI at 3.0 T: Relaxation Times and Image Contrast
Sunday, 1 August 2004   by www.ajronline.org    
Knee, Anterior Cruciate Ligament Injuries (MRI)
Tuesday, 28 March 2006   by www.emedicine.com    
  News & More:
NSAIDs May Worsen Arthritis Inflammation
Monday, 21 November 2022   by www.itnonline.com    
A Knee MRI in Half the Time? It's Possible
Thursday, 8 April 2021   by www.diagnosticimaging.com    
Seniors, patients, astronauts will all benefit from new USask research on bone health
Saturday, 27 February 2021   by www.yorktonthisweek.com    
3D mapping algorithm reads knee MRIs for new arthritis treatments
Thursday, 11 June 2020   by www.healthimaging.com    
MRI T2 Mapping of the Knee Providing Synthetic Morphologic Images: Comparison to Conventional Turbo Spin-Echo MRI
Tuesday, 1 October 2019   by pubs.rsna.org    
Researcher uses MRI to measure joint's geometry and role in severe knee injury
Tuesday, 23 September 2014   by medicalxpress.com    
Abnormalities on MRI predict knee replacement
Monday, 9 March 2015   by medicalxpress.com    
MRI Resources 
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DeviceForum -
related threadsInfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.
 
Magnetic resonance imaging (MRI) is based on the magnetic resonance phenomenon, and is used for medical diagnostic imaging since ca. 1977 (see also MRI History).
The first developed MRI devices were constructed as long narrow tunnels. In the meantime the magnets became shorter and wider. In addition to this short bore magnet design, open MRI machines were created. MRI machines with open design have commonly either horizontal or vertical opposite installed magnets and obtain more space and air around the patient during the MRI test.
The basic hardware components of all MRI systems are the magnet, producing a stable and very intense magnetic field, the gradient coils, creating a variable field and radio frequency (RF) coils which are used to transmit energy and to encode spatial positioning. A computer controls the MRI scanning operation and processes the information.
The range of used field strengths for medical imaging is from 0.15 to 3 T. The open MRI magnets have usually field strength in the range 0.2 Tesla to 0.35 Tesla. The higher field MRI devices are commonly solenoid with short bore superconducting magnets, which provide homogeneous fields of high stability.
There are this different types of magnets:
The majority of superconductive magnets are based on niobium-titanium (NbTi) alloys, which are very reliable and require extremely uniform fields and extreme stability over time, but require a liquid helium cryogenic system to keep the conductors at approximately 4.2 Kelvin (-268.8° Celsius). To maintain this temperature the magnet is enclosed and cooled by a cryogen containing liquid helium (sometimes also nitrogen).
The gradient coils are required to produce a linear variation in field along one direction, and to have high efficiency, low inductance and low resistance, in order to minimize the current requirements and heat deposition. A Maxwell coil usually produces linear variation in field along the z-axis; in the other two axes it is best done using a saddle coil, such as the Golay coil.
The radio frequency coils used to excite the nuclei fall into two main categories; surface coils and volume coils. The essential element for spatial encoding, the gradient coil sub-system of the MRI scanner is responsible for the encoding of specialized contrast such as flow information, diffusion information, and modulation of magnetization for spatial tagging.
An analog to digital converter turns the nuclear magnetic resonance signal to a digital signal. The digital signal is then sent to an image processor for Fourier transformation and the image of the MRI scan is displayed on a monitor.

For Ultrasound Imaging (USI) see Ultrasound Machine at Medical-Ultrasound-Imaging.com.

See also the related poll results: 'In 2010 your scanner will probably work with a field strength of' and 'Most outages of your scanning system are caused by failure of'
Radiology-tip.comradGamma Camera,  Linear Accelerator
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Medical-Ultrasound-Imaging.comUltrasound Machine,  Real-Time Scanner
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• View the DATABASE results for 'Device' (141).Open this link in a new window


• View the NEWS results for 'Device' (29).Open this link in a new window.
 
Further Reading:
  News & More:
small-steps-can-yield-big-energy-savings-and-cut-emissions-mris
Thursday, 27 April 2023   by www.itnonline.com    
Portable MRI can detect brain abnormalities at bedside
Tuesday, 8 September 2020   by news.yale.edu    
Point-of-Care MRI Secures FDA 510(k) Clearance
Thursday, 30 April 2020   by www.diagnosticimaging.com    
World's First Portable MRI Cleared by FDA
Monday, 17 February 2020   by www.medgadget.com    
Low Power MRI Helps Image Lungs, Brings Costs Down
Thursday, 10 October 2019   by www.medgadget.com    
Cheap, portable scanners could transform brain imaging. But how will scientists deliver the data?
Tuesday, 16 April 2019   by www.sciencemag.org    
The world's strongest MRI machines are pushing human imaging to new limits
Wednesday, 31 October 2018   by www.nature.com    
Kyoto University and Canon reduce cost of MRI scanner to one tenth
Monday, 11 January 2016   by www.electronicsweekly.com    
A transportable MRI machine to speed up the diagnosis and treatment of stroke patients
Wednesday, 22 April 2015   by medicalxpress.com    
Portable 'battlefield MRI' comes out of the lab
Thursday, 30 April 2015   by physicsworld.com    
Chemists develop MRI technique for peeking inside battery-like devices
Friday, 1 August 2014   by www.eurekalert.org    
New devices doubles down to detect and map brain signals
Monday, 23 July 2012   by scienceblog.com    
MRI Resources 
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