(N) The SI units is moles/m
3.
Definition: The concentration of nuclei in tissue processing at the
Larmor frequency in a given region; one of the principal determinants of the strength of the
NMR signal from the region.
For water, there are about 1.1 x 105 moles of hydrogen per m
3, or 0.11 moles of hydrogen/cm
3.
The
signal intensity measured is related to the square of the xy-magnetization, which in a SE
pulse sequence is given by
Mxy = Mxy0(1-exp(-TR/T1)) exp(-TE/T2)
where Mxy0 = Mz0 is proportional to the
proton or
spin density, and corresponds to the z-magnetization present at zero time of the experiment when it is tilted into the xy-plane.
True
spin density is not imaged directly, but must be calculated from signals received with different
interpulse times. The
spin density
contrast can be generated by using a long TR and
sampling the data immediately after the
RF pulse (with a TE as short as possible).