The normal image display, at which the grey scale of a display element corresponds to the magnitude of the MR signal.

Mallinckrodt, a Tyco Healthcare company makes and distributes products for respiratory care; bulk and dosage pharmaceuticals, primarily for pain relief and addiction therapy; and imaging agents for magnetic resonance, ultrasound, X-ray, and nuclear medicine applications. With worldwide manufacturing and distribution facilities, as well as worldwide sales offices, Mallinckrodt sells its products worldwide.
GastroMARK® is marketed in the United States by Mallinckrodt, Inc.

In June 2007 Tyco International Ltd. completed the separation of its healthcare business, which is named Covidien. Mallinckrodt, Inc. is now part of Covidien Ltd.

MRI Contrast Agents:

Short name: Mn-DPDP
This MRI contrast agent is a chelate complex of the paramagnetic metal ion manganese (Mn) and fodipir. Mn-DPDP (Teslascan) shortens the longitudinal relaxation time and is used for the T1 weighted enhancement of MR images. Mangafodipir trisodium accumulates after intravenous injection in the healthy tissue of the liver and improves the detection, localization, characterization, and evaluation of lesions of the liver, pancreas, but can also be used in cardiac MRI.
See also Hepatobiliary Chelates and Teslascan®.
The United States Food and Drug Administration (FDA) has granted marketing clearance 1997, to Nycomed Amersham's MRI contrast medium. Nycomed/Amersham, now GE Healthcare markets the product under the trade name Teslascan®.

Manganese chloride (MnCl2) is used as an oral contrast agent (LumenHance®) for MRI of the abdomen and/or pelvis. MnCl2 has also been used in magnetic resonance imaging of animals to maximize the contrast of different tissues e.g. in mice and crayfish with different injection methods. Caused by the hepatic uptake, manganese chloride has potential as a hepatobiliary contrast agent.
Manganese chloride is produced by the reaction of hydrochloric acid with manganese oxide or manganese carbonate. In an aqueous solution, manganese chloride can serve as phantom fluid, used for e.g. the daily quality assurance.

See also Classifications, Characteristics, etc.

Short name: PEG-APD (MnHA/PEG-APD), generic name: Manganese substituted hydroxylapatite, central moiety: Mn2+, relaxivity: r1=21.7, r2=26.9, B0=1.0 T
An intravascular MRI contrast agent under development (preclin.) for MR angiography.