(PWI - Perfusion Weighted Imaging) Perfusion MRI techniques (e.g. PRESTO - Principles of Echo Shifting using a Train of Observations) are sensitive to microscopic levels of blood flow. Contrast enhanced relative cerebral blood volume (rCBV) is the most used perfusion imaging. Both, the ready availability and the T2* susceptibility effects of gadolinium, rather than the T1 shortening effects make gadolinium a suitable agent for use in perfusion imaging. Susceptibility here refers to the loss of MR signal, most marked on T2* (gradient echo)-weighted and T2 (spin echo)-weighted sequences, caused by the magnetic field-distorting effects of paramagnetic substances.
T2* perfusion uses dynamic sequences based on multi or single shot techniques. The T2* (T2) MRI signal drop within or across a brain region is caused by spin dephasing during the rapid passage of contrast agent through the capillary bed. The signal decrease is used to compute the relative perfusion to that region. The bolus through the tissue is only a few seconds, high temporal resolution imaging is required to obtain sequential images during the wash in and wash out of the contrast material and therefore, resolve the first pass of the tracer. Due to the high temporal resolution, processing and calculation of hemodynamic maps are available (including mean transit time (MTT), time to peak (TTP), time of arrival (T0), negative integral (N1) and index.
An important neuroradiological indication for MRI is the evaluation of incipient or acute stroke via perfusion and diffusion imaging. Diffusion imaging can demonstrate the central effect of a stroke on the brain, whereas perfusion imaging visualizes the larger 'second ring' delineating blood flow and blood volume. Qualitative and in some instances quantitative (e.g. quantitative imaging of perfusion using a single subtraction) maps of regional organ perfusion can thus be obtained.
Echo planar and potentially echo volume techniques together with appropriate computing power offer real time images of dynamic variations in water characteristics reflecting perfusion, diffusion, oxygenation (see also Oxygen Mapping) and flow.
Another type of perfusion MR imaging allows the evaluation of myocardial ischemia during pharmacologic stress. After e.g., adenosine infusion, multiple short axis views (see cardiac axes) of the heart are obtained during the administration of gadolinium contrast. Ischemic areas show up as areas of delayed and diminished enhancement. The MRI stress perfusion has been shown to be more accurate than nuclear SPECT exams. Myocardial late enhancement and stress perfusion imaging can also be performed during the same cardiac MRI examination.

(PROPELLER) The PROPELLER MRI technique reduces the sensitivity to various sources of image artifacts (e.g., motion artifact, field inhomogeneity artifact, eddy current artifact). PROPELLER can be used with gradient echo and turbo spin echo sequences in a wide range of applications to improve the image quality, for example cardiac MRI, brain MRI, and pediatric examinations.

A magnet whose magnetic field originates from permanently ferromagnetic materials (permanent magnets) to generate a magnetic field between the two poles of the magnet. There is no requirement for additional electrical power or cooling, and the iron-core structure of the magnet leads to a limited fringe field and no missile effect. Due to weight considerations, permanent magnets are usually limited to maximum field strengths of 0.4 T. The main disadvantages of a permanent magnet are the cost of the magnet itself and supporting structures and the varying changes in the magnetic field. Field homogeneity can be an on-going problem in permanent magnets.

(m) Tendency of a substance to concentrate magnetic field, m = B/H.

An artificial object of known size and composition that is imaged to test, adjust or monitor an MRI systems homogeneity, imaging performance and orientation aspects. A phantom is usually a fluid-filled container or bottle often filled with a plastic structure of various sizes and shapes.

See also Daily Quality Assurance.