In MR, saturation is a nonequilibrium state with no net
magnetization. The same amount of nuclear spins is aligned against and with the
magnetic field. Saturation methods like FatSat, SPIR etc., work with a
frequency selective saturation pulse for a specific
chemical shift applied before the actual sequence starts. This saturation pulse adjusts the
magnetization from tissue components to zero. The hydrogen nuclei of fat and water resonate at different frequencies, which makes it possible to excite just the fat with repeatedly applying RF pulses at the
Larmor frequency with
interpulse times compared to T1. The resulting signal is then destroyed with a
gradient pulse (
Spoiler Gradient Pulse). Fat is the chemical compound to be saturated at a
fat saturation sequence. When the actual sequence follows, (e.g., a
spin echo sequence) the unwanted suppressed component will not resonate.
See also
Saturation Recovery.