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(FOV) Defined as the size of the two or three dimensional spatial encoding area of the image. Usually defined in units of mm². The FOV is the square image area that contains the object of interest to be measured. The smaller the FOV, the higher the resolution and the smaller the voxel size but the lower the measured signal.
Useful for decreasing the scantime is a field of view different in the frequency and phase encoding directions ( rectangular field of view - RFOV).
The magnetic field homogeneity decreases as more tissue is imaged (greater FOV). As a result the precessional frequencies change across the imaging volume. That can be a problem for fat suppression imaging. This fat is precessing at the expected frequency only in the center of the imaging volume. E.g. frequency specific fat saturation pulses become less effective when the field of view is increased. It is best to use smaller field of views when applying fat saturation pulses.
Image Guidance
Smaller FOV required higher gradient strength and concludes low signal. Therefore you have to find a compromise between these factors.
The right choice of the field of view is important for MR image quality. When utilizing small field of views and scanning at a distance from the isocenter (more problems with artifacts) it is obviously important to ensure that the region of interest is within the scanning volume.
A smaller FOV in one direction is available with the function rectangular field of view (RFOV).
See also Field Inhomogeneity Artifact. | | | | | | • View the DATABASE results for 'Field of View' (27).
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Flow phenomena are intrinsic processes in the human body. Organs like the heart, the brain or the kidneys need large amounts of blood and the blood flow varies depending on their degree of activity. Magnetic resonance imaging has a high sensitivity to flow and offers accurate, reproducible, and noninvasive methods for the quantification of flow. MRI flow measurements yield information of blood supply of of various vessels and tissues as well as cerebro spinal fluid movement.
Flow can be measured and visualized with different pulse sequences (e.g. phase contrast sequence, cine sequence, time of flight angiography) or contrast enhanced MRI methods (e.g. perfusion imaging, arterial spin labeling).
The blood volume per time (flow) is measured in: cm3/s or ml/min. The blood flow-velocity decreases gradually dependent on the vessel diameter, from approximately 50 cm per second in arteries with a diameter of around 6 mm like the carotids, to 0.3 cm per second in the small arterioles.
Different flow types in human body:
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Behaves like stationary tissue, the signal intensity depends on T1, T2 and PD = Stagnant flow
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Flow with consistent velocities across a vessel = Laminar flow
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Laminar flow passes through a stricture or stenosis (in the center fast flow, near the walls the flow spirals) = Vortex flow
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Flow at different velocities that fluctuates = Turbulent flow
See also Flow Effects, Flow Artifact, Flow Quantification, Flow Related Enhancement, Flow Encoding, Flow Void, Cerebro Spinal Fluid Pulsation Artifact, Cardiovascular Imaging and Cardiac MRI. | | | | | | • View the DATABASE results for 'Flow' (113).
| | | • View the NEWS results for 'Flow' (7).
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Motion of material being imaged, particularly flowing blood, can result in many possible effects in the images.
Fast moving blood produces flow voids,
blood flowing in to the outer slices of an imaging volume produces high signals ( flow related enhancement, entry slice phenomenon),
pulsatile flow creates ghost images of the vessel extending across the image in the phase encoding direction (image misregistration).
Flow-related dephasing occurring when spin isochromats are moving with different velocities in an external gradient field G so that they acquire different phases. When these phases vary by more then 180° within a voxel, substantial spin dephasing results leading to considerable intravascular signal loss.
These effects can be understood as caused by time of flight effects (washout or washin due to motion of nuclei between two consecutive spatially selective RF excitations, repeated in times on the order of, or shorter than the relaxation times of blood) or phase shifts (delay between phase encoding and frequency encoding) that can be acquired by excited spins moving along magnetic field gradients.
The inconsistency of the signal resulting from pulsatile flow can lead to artifacts in the image. The flow effects can also be exploited for MR angiography or flow measurements.
See also Flow Artifact. | | | | | | • View the DATABASE results for 'Flow Effects' (16).
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Gastrointestinal (GI) superparamagnetic contrast agents are used in MRI to improve the visualization of e.g., the intestinal tract, the pancreas (see MRCP), etc.
Disadvantages are susceptibility artifacts e.g., dependent on delayed imaging or large volumes resulting in artifacts in the colon and distal small bowel loops related to higher concentration of the particles and absorption of the fluid.
Different types of MRI gastrointestinal superparamagnetic contrast agents:
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Magnetite albumin microsphere
Usually gastrointestinal superparamagnetic contrast media consist of small iron oxide crystals (ferrites), which produce a signal reduction in the stomach and bowel after oral administration. The T2 shortening caused by these particles is produced from the local magnetic field inhomogeneities associated with the large magnetic moments of superparamagnetic particles. Ferrites are iron oxides of the general formula Fe203.MO, where M is a divalent metal ion and may be mixed with Fe3O4 in different preparations.
Ferrites can produce symptoms of nausea after oral administration, as well as flatulence and a transient rise in serum iron. Embedding in inert substances reduce side effects by decreasing the absorption and interaction with body tissues. Combining these contrast materials with polymers such as polyethylene glycol or cellulose, or with sugars such as dextrose, results in improved T1 and/or T2 relaxivity compared with that of the contrast agent alone.
See also Negative Oral Contrast Agents, Gastrointestinal Diamagnetic Contrast Agents, Relaxivity, and Combination Oral Contrast Agents. | | | | • View the DATABASE results for 'Gastrointestinal Superparamagnetic Contrast Agents' (6).
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