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Blood Flow-Velocity
 
Velocity of flowing blood, usually measured in cm/s. It is always zero at the vessel wall and the velocity profile across a vessel can have various shapes depending upon the type of flow being observed. Laminar flow giving rise to a laminar velocity profile, plug flow giving rise to a flat velocity profile and disturbed flow can be distinguished.
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Phase Contrast AngiographyMRI Resource Directory:
 - MRA -
 
(PCA) With this method images of the blood flow-velocity (or any other movement of tissue) are produced. The MRI signal contains both amplitude and phase information. The phase information can be used with subtraction of images with and without a velocity encoding gradient. The signal will be directly proportional to the velocity because of the relation between blood flow-velocity and signal intensity.
This is the strength of PCA, complete suppression of stationary tissue (no velocity - no signal), the direct velocity of flow is being imaged, while in TOF (Inflow) angiography, tissue with short T1 (fat or methaemoglobin) might be visualized.
The strength of the gradient determines the sensitivity to flow. It is set by setting the aliasing or encoding velocity (VENC). Unfortunately, phase sensitization can only be acquired along one axis at a time. Therefore, phase contrast angiographic techniques tend to be 4 times slower than TOF techniques with the same matrix.

See also Phase Contrast Sequence, Magnetic Resonance Angiography, Contrast Enhanced Magnetic Resonance Angiography, Flow Effects and Flow Quantification.
 
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Further Reading:
  Basics:
Magnetic resonance angiography: current status and future directions
Wednesday, 9 March 2011   by www.jcmr-online.com    
  News & More:
MR–ANGIOGRAPHY(.pdf)
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FlowForum -
related threads
 
Flow phenomena are intrinsic processes in the human body. Organs like the heart, the brain or the kidneys need large amounts of blood and the blood flow varies depending on their degree of activity. Magnetic resonance imaging has a high sensitivity to flow and offers accurate, reproducible, and noninvasive methods for the quantification of flow. MRI flow measurements yield information of blood supply of of various vessels and tissues as well as cerebro spinal fluid movement.
Flow can be measured and visualized with different pulse sequences (e.g. phase contrast sequence, cine sequence, time of flight angiography) or contrast enhanced MRI methods (e.g. perfusion imaging, arterial spin labeling).
The blood volume per time (flow) is measured in: cm3/s or ml/min. The blood flow-velocity decreases gradually dependent on the vessel diameter, from approximately 50 cm per second in arteries with a diameter of around 6 mm like the carotids, to 0.3 cm per second in the small arterioles.

Different flow types in human body:
Behaves like stationary tissue, the signal intensity depends on T1, T2 and PD = Stagnant flow
Flow with consistent velocities across a vessel = Laminar flow
Laminar flow passes through a stricture or stenosis (in the center fast flow, near the walls the flow spirals) = Vortex flow
Flow at different velocities that fluctuates = Turbulent flow

See also Flow Effects, Flow Artifact, Flow Quantification, Flow Related Enhancement, Flow Encoding, Flow Void, Cerebro Spinal Fluid Pulsation Artifact, Cardiovascular Imaging and Cardiac MRI.
 
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Further Reading:
  News & More:
The super-fast MRI scan that could revolutionise heart failure diagnosis
Wednesday, 21 September 2022   by www.eurekalert.org    
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Magnetic Resonance Angiography MRAMRI Resource Directory:
 - MRA -
 
(MRA) Magnetic resonance angiography is a medical imaging technique to visualize blood filled structures, including arteries, veins and the heart chambers. This MRI technique creates soft tissue contrast between blood vessels and surrounding tissues primarily created by flow, rather than displaying the vessel lumen. There are bright blood and black blood MRA techniques, named according to the appearance of the blood vessels. With this different MRA techniques both, the blood flow and the condition of the blood vessel walls can be seen. Flow effects in MRI can produce a range of artifacts. MRA takes advantage of these artifacts to create predictable image contrast due to the nature of flow.
Technical parameters of the MRA sequence greatly affect the sensitivity of the images to flow with different velocities or directions, turbulent flow and vessel size.
This are the three main types of MRA:
All angiographic techniques differentially enhance vascular MR signal. The names of the bright blood techniques TOF and PCA reflect the physical properties of flowing blood that were exploited to make the vessels appear bright. Contrast enhanced magnetic resonance angiography creates the angiographic effect by using an intravenously administered MR contrast agent to selectively shorten the T1 of blood and thereby cause the vessels to appear bright on T1 weighted images.
MRA images optimally display areas of constant blood flow-velocity, but there are many situations where the flow within a voxel has non-uniform speed or direction. In a diseased vessel these patterns are even more complex. Similar loss of streamline flow occurs at all vessel junctions and stenoses, and in regions of mural thrombosis. It results in a loss of signal, due to the loss of phase coherence between spins in the voxel.
This signal loss, usually only noticeable distal to a stenosis, used to be an obvious characteristic of MRA images. It is minimized by using small voxels and the shortest possible TE. Signal loss from disorganized flow is most noticeable in TOF imaging but also affects the PCA images.
Indications to perform a magnetic resonance angiography (MRA):
Detection of aneurysms and dissections
Evaluation of the vessel anatomy, including variants
Blockage by a blood clot or stenosis of the blood vessel caused by plaques (the buildup of fat and calcium deposits)

Conventional angiography or computerized tomography angiography (CT angiography) may be needed after MRA if a problem (such as an aneurysm) is present or if surgery is being considered.

See also Magnetic Resonance Imaging MRI.
 
Images, Movies, Sliders:
 CE-MRA of the Carotid Arteries Colored MIP  Open this link in a new window
    
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 CE MRA of the Aorta  Open this link in a new window
    
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 TOF-MRA Circle of Willis Inverted MIP  Open this link in a new window
    

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 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
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Radiology-tip.comradCT Angiography,  Angiogram
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Medical-Ultrasound-Imaging.comVascular Ultrasound,  Intravascular Ultrasound
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• View the DATABASE results for 'Magnetic Resonance Angiography MRA' (3).Open this link in a new window


• View the NEWS results for 'Magnetic Resonance Angiography MRA' (10).Open this link in a new window.
 
Further Reading:
  Basics:
Magnetic resonance angiography: current status and future directions
Wednesday, 9 March 2011   by www.jcmr-online.com    
MR–ANGIOGRAPHY(.pdf)
  News & More:
3-D-printed model of stenotic intracranial artery enables vessel-wall MRI standardization
Friday, 14 April 2017   by www.eurekalert.org    
Conventional MRI and MR Angiography of Stroke
2012   by www.mc.vanderbilt.edu    
MR Angiography Highly Accurate In Detecting Blocked Arteries
Thursday, 1 February 2007   by www.sciencedaily.com    
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Magnetohydrodynamic Effect
 
This effect is an additional electrical charge generated by ions in blood (loaded particles) moving perpendicular to the magnetic field. At 1.5 T, no significant changes are expected; at 6.0 T a 10% blood pressure change is expected. A blood pressure increase is predicted theoretically for a field of 10 T. This is claimed to be caused by interaction of induced electrical potentials and currents within a solution, e.g. blood, and an electrical volume force causing a retardation in the direction opposite to the fluid flow. This decrease in blood flow-velocity must be compensated for by an elevation in pressure.
Static magnetic field gradients of 0.01 T/cm (100 G/cm) make no significant difference in the membrane transport processes. The influence of a static magnetic field upon erythrocytes is not sufficient to provoke sedimentation, as long as there is a normal blood circulation.
mri safety guidance
MRI Safety Guidance
The magnetohydrodynamic effect which results from a voltage occurring across a vessel in a magnetic field, is irrelevant at the field strengths used.
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Further Reading:
  News & More:
Measuring magnetic force field distributions in microfluidic devices: Experimental and numerical approaches
Saturday, 2 December 2023   by analyticalsciencejournals.onlinelibrary.wiley.com    
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