FSE optimization runs a preliminary TR period at the central slice and compares the phase of each echo in the echo train. If the phases do not compliment each other the RF is recalibrated and then the entire sequence is run. If there is an error in calibrating the phases of each of the echoes artifacts will appear.
Further Reading:
Basics:
RARE Monday, 3 December 2012 by www2.warwick.ac.uk
(IR-FSPGR) This sequence uses an inversion pulse followed by a spoiled low flip angle and short TR gradientecho train to collect all partition data.
The 3D-IR-FSPGR uses centric ordering of Gz. The selected TI is also the effective TI. The centric reordering strategy can lead to image blurring if a steady state is not achieved quickly with low flip angles (less than 20°).
(HASTE) A pulse sequence with data acquisition after an initial preparation pulse for contrast enhancement with the use of a very long echo train (Single shotTSE), whereat each echo is individually phase encoded.
This technique is a heavily T2 weighted, high speed sequence with partial Fourier technique, a great sensitivity for fluid detection and a fast acquisition time of about 1 sec per slice. This advantage makes it possible for using breath-hold with excellent motionless MRI, e.g. used for liver and lung imaging.
Lung imaging is furthermore a challenge in MRI because of the predominance of air within the lungs and associated susceptibility issues as well as low signal to noise of the inflated lung parenchyma. Cardiac and respiratory triggered or breath hold sequences allow diagnostic imaging, however a comparable image quality with computed tomography is still difficult to achieve.
Assumptions for lung MRI:
Very short transverse relaxation times and significant diffusion yielding short T2 (30-70 msec), short T2* (1-3 msec), and additional long T1 relaxation times (1300-1500 msec).
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The extreme short T2 values are responsible for a fast signal decay during a single shot readout, resulting in blurring.