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(PCA) With this method images of the blood flow-velocity (or any other movement of tissue) are produced.
The MRI signal contains both amplitude and phase information.
The phase information can be used with subtraction of images with and without a velocity encodinggradient. The signal will be directly proportional to the velocity because of the relation between blood flow-velocity and signal intensity.
This is the strength of PCA, complete suppression of stationary tissue (no velocity - no signal), the direct velocity of flow is being imaged, while in TOF (Inflow) angiography, tissue with short T1 (fat or methaemoglobin) might be visualized.
The strength of the gradient determines the sensitivity
to flow. It is set by setting the aliasing or encoding velocity (VENC). Unfortunately, phase sensitization can only be acquired along one axis at a time. Therefore, phasecontrast angiographic techniques tend to be 4 times slower than TOF techniques with the same matrix.
The entry slice phenomenon arise in MRI when blood with unsaturated spins flows in the observed slice(s). These spins will emit a strong signal, because of their unsaturated status (flow related enhancement). The number of slices affected depends on the flowvelocity and the slice thickness; the direction of flow determines which slices are affected.
Time of FlightMRA is based on this entry slice phenomenon.
Pulsatile cerebro spinal fluid flow produces ghost artifacts that are superimposed in the image.
Image Guidance
Flow compensation should be used to reduce these artifacts. This applies an additional gradient to eliminate phase differences for both stationary and moving spins at the echo time. At TE no phase differences is measured. If flow compensation is applied and there are still flow artifacts, cardiac triggering is an additional option to reduce these artifacts.
See also Motion Artifact.
A type of MRA used to display slow flow across a large volume with a good resolution.
Two data volumes are measured; the flow-rephased images show bright signal, the flow-dephased image show dark flow, whereby in both data volumes the signal of the stationary tissue looks the same. The data volumes are subtracted and the signal intensity of flowing blood remains.