(DTI) Diffusion tensor imaging is the more sophisticated form of DWI, which allows for the determination of directionality as well as the magnitude of water diffusion. This kind of MR imaging can estimates damage to nerve fibers that connect the area of the brain affected by the stroke to brain regions that are distant from it, and can be used to determine the effectiveness of stroke prevention medications.
DTI (FiberTrak) enables to visualize white matter fibers in the brain and can map (trace image) subtle changes in the white matter associated with diseases such as multiple sclerosis and epilepsy, as well as assessing diseases where the brain's wiring is abnormal, such as schizophrenia.
The fractional anisotropy (FA) gives information about the shape of the diffusion tensor at each voxel. The FA is based on the normalized variance of the eigenvalues. The fractional anisotropy reflects differences between an isotropic diffusion and a linear diffusion. The FA range is between 0 and 1 (0 = isotropic diffusion, 1 = highly directional).
The development of new imaging methods and some useful analysis techniques, such as 3-dimensional anisotropy contrast (3DAC) and spatial tracking of the diffusion tensor tractography (DTT), are currently under study.

Volumetric imaging is a 3D technique where all the MRI signals are collected from the entire tissue sample and imaged as a whole entity, therefore providing a high signal to noise ratio. The acquisition of isotropic voxels or thin slices with high spatial resolution allows to create multiplanar reconstructions in all planes; a compensation for the usually longer scan time. The acquisition time can be reduced by parallel imaging technique.
New T2 weighted variants of 3D sequences (FSE-XETA, T2-SPACE, VISTA) have been introduced that differ from conventional FSE sequences. An echo train containing up to 200 echoes obtained at a minimum echo spacing allows very fast acquisition. A flip angle modulation (flip angle sweep - FAS) during the FSE readout carries magnetization as long as possible to avoid blurring and provide optimal signal at the effective echo time. This type of imaging is well suited for brain and spine MRI procedures.
Newer T1 weighted variants include Liver Acquisition with Volume Acquisition (LAVA) and T1W High Resolution Isotropic Volume Examination (THRIVE), which have advantages for dynamic breath hold imaging in liver and abdominal examinations.

See also Volume Imaging, 3 Dimensional Imaging.

(CE MRA) Contrast enhanced MR angiography is based on the T1 values of blood, the surrounding tissue, and paramagnetic contrast agent.
T1-shortening contrast agents reduces the T1 value of the blood (approximately to 50 msec, shorter than that of the surrounding tissues) and allow the visualization of blood vessels, as the images are no longer dependent primarily on the inflow effect of the blood. Contrast enhanced MRA is performed with a short TR to have low signal (due to the longer T1) from the stationary tissue, short scan time to facilitate breath hold imaging, short TE to minimize T2* effects and a bolus injection of a sufficient dose of a gadolinium chelate.
Images of the region of interest are performed with 3D spoiled gradient echo pulse sequences. The enhancement is maximized by timing the contrast agent injection such that the period of maximum arterial concentration corresponds to the k-space acquisition. Different techniques are used to ensure optimal contrast of the arteries e.g., bolus timing, automatic bolus detection, bolus tracking, care bolus. A high resolution with near isotropic voxels and minimal pulsatility and misregistration artifacts should be striven for. The postprocessing with the maximum intensity projection (MIP) enables different views of the 3D data set.
Unlike conventional MRA techniques based on velocity dependent inflow or phase shift techniques, contrast enhanced MRA exploits the gadolinium induced T1-shortening effects. CE MRA reduces or eliminates most of the artifacts of time of flight angiography or phase contrast angiography. Advantages are the possibility of in plane imaging of the blood vessels, which allows to examine large parts in a short time and high resolution scans in one breath hold. CE MRA has found a wide acceptance in the clinical routine, caused by the advantages:

(FRFSE, FR-FSE) The fast relaxation fast spin echo sequence provides high signal intensity of fluids even with short repetition times, and can be used with parallel imaging techniques for short breath hold imaging or respiratory gating for free-breathing, high isotropic resolution MR imaging. After signal decay at the end of the echo train, a negative 90° pulse align spins with long T2 from the transverse plane to the longitudinal plane, leading to a much faster recovery of tissues with long T2 time to the equilibrium and thus better contrast between tissues with long and short T2.
Fast relaxation FSE has advantages also for volumetric imaging as the TR can be substantially reduced and thus the scan time. The sequence can be post processed with maximum intensity projection, surface or volume rendering algorithms to visualize anatomical details in brain or spine MRI. Cerebro spinal fluid pulsation artifacts, often problematic in the cervical or thoracic spine may be reduced by radial sampling, in particular when combined with acquisitions of the PROPELLER type.

See also Fast spin echo, Driven Equilibrium.

This parametric images reflect the similarity between the anisotropic diffusion of each pixel and that of its neighbors.