(DTI)
Diffusion tensor imaging is the more sophisticated form of
DWI, which allows for the determination of directionality as well as the
magnitude of water
diffusion. This kind of
MR imaging can estimates damage to nerve fibers that connect the area of the
brain affected by the stroke to
brain regions that are distant from it, and can be used to determine the effectiveness of stroke prevention medications.
DTI (FiberTrak) enables to visualize white
matter fibers in the
brain and can map (
trace image) subtle changes in the white
matter associated with diseases such as multiple sclerosis and epilepsy, as well as assessing diseases where the brain's wiring is abnormal, such as schizophrenia.
The fractional anisotropy (FA) gives information about the
shape of
the
diffusion tensor at each
voxel. The FA is based on the normalized
variance of the
eigenvalues. The fractional anisotropy reflects differences between an
isotropic diffusion and a
linear
diffusion. The FA range is between 0 and 1 (0 =
isotropic diffusion, 1 = highly directional).
The development of new imaging methods and some useful analysis techniques, such as 3-dimensional anisotropy
contrast (3DAC) and spatial tracking of the
diffusion tensor tractography (DTT), are currently under study.