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News  (181)  Resources  (43)  Forum  (13)  
 
MRI History
 
Sir Joseph Larmor (1857-1942) developed the equation that the angular frequency of precession of the nuclear spins being proportional to the strength of the magnetic field. [Larmor relationship]
In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
In 1975, Richard Ernst introduced 2D NMR using phase and frequency encoding, and the Fourier Transform. Instead of Paul Lauterbur's back-projection, he timely switched magnetic field gradients ('NMR Fourier Zeugmatography'). [This basic reconstruction method is the basis of current MRI techniques.]
1977/78: First images could be presented. A cross section through a finger by Peter Mansfield and Andrew A. Maudsley. Peter Mansfield also could present the first image through the abdomen.
In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
In 1984, FONAR Corporation receives FDA approval for its first MRI scanner.
1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH (fast low angle shot) sequence.
1988: Schering's MAGNEVIST gets its first approval by the FDA.
In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
 
Images, Movies, Sliders:
 Cardiac Infarct Short Axis Cine Overview  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 
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• Related Searches:
    • High Field MRI
    • Brain MRI
    • Device
    • Low Field MRI
    • Magnetic Resonance Imaging MRI
 
Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
Fonar Our History
   by www.fonar.com    
  News & More:
Scientists win Nobels for work on MRI
Tuesday, 10 June 2003   by usatoday30.usatoday.com    
2001 Lemelson-MIT Lifetime Achievement Award Winner
   by web.mit.edu    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
MRI Resources 
Universities - Abdominal Imaging - Online Books - Stimulator pool - Cardiovascular Imaging - Collections
 
Echo Planar ImagingInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.MRI Resource Directory:
 - Sequences -
 
Echo Planar Imaging Timing Diagram (EPI) Echo planar imaging is one of the early magnetic resonance imaging sequences (also known as Intascan), used in applications like diffusion, perfusion, and functional magnetic resonance imaging. Other sequences acquire one k-space line at each phase encoding step. When the echo planar imaging acquisition strategy is used, the complete image is formed from a single data sample (all k-space lines are measured in one repetition time) of a gradient echo or spin echo sequence (see single shot technique) with an acquisition time of about 20 to 100 ms. The pulse sequence timing diagram illustrates an echo planar imaging sequence from spin echo type with eight echo train pulses. (See also Pulse Sequence Timing Diagram, for a description of the components.)
In case of a gradient echo based EPI sequence the initial part is very similar to a standard gradient echo sequence. By periodically fast reversing the readout or frequency encoding gradient, a train of echoes is generated.
EPI requires higher performance from the MRI scanner like much larger gradient amplitudes. The scan time is dependent on the spatial resolution required, the strength of the applied gradient fields and the time the machine needs to ramp the gradients.
In EPI, there is water fat shift in the phase encoding direction due to phase accumulations. To minimize water fat shift (WFS) in the phase direction fat suppression and a wide bandwidth (BW) are selected. On a typical EPI sequence, there is virtually no time at all for the flat top of the gradient waveform. The problem is solved by "ramp sampling" through most of the rise and fall time to improve image resolution.
The benefits of the fast imaging time are not without cost. EPI is relatively demanding on the scanner hardware, in particular on gradient strengths, gradient switching times, and receiver bandwidth. In addition, EPI is extremely sensitive to image artifacts and distortions.
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• View the DATABASE results for 'Echo Planar Imaging' (19).Open this link in a new window


• View the NEWS results for 'Echo Planar Imaging' (1).Open this link in a new window.
 
Further Reading:
  Basics:
New Imaging Method Makes Brain Scans 7 Times Faster
Sunday, 9 January 2011   by www.dailytech.com    
MRI Resources 
Devices - Resources - Hospitals - Developers - Software - Anatomy
 
Virgo™InfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.MRI Resource Directory:
 - Devices -
 
www.canamglobal.com/mri/virgomri.html From Millennium Technology Inc. This open C-shaped MRI system eases patient comfort and technologist maneuverability. This low cost scanner is build for a wide range of applications. The Virgo™ patient table is detachable and moves on easy rolling castors. Able to accommodate patient weights up to 160 kg, the tabletop has a range of motion of 30 cm in the lateral direction and 90cm in the longitudinal direction. Images generated with this scanner can only be viewed (without data loss) on Millennium's proprietary viewing software.
Device Information and Specification
CLINICAL APPLICATION
Whole body
CONFIGURATION
C shaped
SYNCHRONIZATION
Standard cardiac gating, ECG/peripheral, respiratory gating
PULSE SEQUENCES
2D Spin Echo (single and multi-echo), 2D Inversion Recovery, 2D Sequential and 3D Volume Gradient Echo, 2D and 3D Spoiled Gradient Echo
IMAGING MODES
Localizer, single slice, multislice, volume, fast, POMP, multi slab, cine, slice and frequency zip, extended dynamic range, tailored RF
TR
steps of 1 msec
TE
steps of 1 msec
SINGLE/MULTI SLICE
Simultaneous scan and reconstruction;; 100 images/second reconstruction
400 mm
2D : 2 mm; 3D : 0.5 mm
MEASURING MATRIX
512x512
PIXEL INTENSITY
256 gray levels
MAGNET TYPE
Permanent
BORE DIAMETER
or Vertical Gap
44 cm
STRENGTH
15 mT/m
5-GAUSS FRINGE FIELD
3 m/3 m
Passive
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Searchterm 'MRI Image' was also found in the following services: 
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Signa Infinity 1.5T™ with ExciteInfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.MRI Resource Directory:
 - Devices -
 
www.gehealthcare.com/usen/mr/s_excite15/index.html From GE Healthcare;
'EXCITE technology has the potential to open the door to new imaging techniques and clinical applications, leaping beyond conventional two and three-dimensional MRI to true 4D imaging that will improve the diagnosis of disease throughout the human body from head to foot.' Robert R. Edelman, M.D., Professor of Radiology at Northwestern University Medical School and Chairman, Department of Radiology, at Evanston Northwestern Healthcare.
Device Information and Specification
CLINICAL APPLICATION
Whole body
CONFIGURATION
Short bore
Head and body coil standard; all other coils optional; open architecture makes system compatible with a wide selection of coils
Optional 2D/3D brain and prostate
SYNCHRONIZATION
ECG/peripheral, respiratory gating, (SmartPrep, SmartStep)
PULSE SEQUENCES
Standard: SE, IR, 2D/3D GRE and SPGR, Angiography: 2D/3D TOF, 2D/3D Phase Contrast;; 2D/3D FSE, 2D/3D FGRE and FSPGR, SSFP, FLAIR, EPI, optional: 2D/3D Fiesta, FGRET, Spiral, Tensor
IMAGING MODES
Localizer, single slice, multislice, volume, fast, POMP, multi slab, cine
TR
1.3 to 12000 msec in increments of 1 msec
TE
0.4 to 2000 msec in increments of 1 msec
SINGLE/MULTI SLICE
Simultaneous scan and reconstruction;; up to 200 or 400 images per second
1 cm to 48 cm continuous
2D 0.7 mm to 20 mm; 3D 0.1 mm to 5 mm
1028 x 1024
MEASURING MATRIX
128x512 steps 32 phase encode
PIXEL INTENSITY
256 gray levels
0.08 mm; 0.02 mm optional
MAGNET WEIGHT
3863 kg
H*W*D
172 x 208 x 216 cm
POWER REQUIREMENTS
480 or 380/415
COOLING SYSTEM TYPE
Closed-loop water-cooled gradient
CRYOGEN USE, L/hr
less than 0.03 L/hr liquid helium
STRENGTH
SmartSpeed 23 mT/m, HiSpeed Plus 33 mT/m, EchoSpeed Plus 33 mT/m
5-GAUSS FRINGE FIELD
4.0 m x 2.8 m axial x radial
Active
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• View the DATABASE results for 'Signa Infinity 1.5T™ with Excite' (2).Open this link in a new window

MRI Resources 
Open Directory Project - Safety Products - Spectroscopy - Most Wanted - MRI Centers - Corporations
 
Signa OpenSpeed™InfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.MRI Resource Directory:
 - Devices -
 
www.gehealthcare.com/usen/mr/open_speed/index.html From GE Healthcare;
a friendly and less confining appearance targets the 7% of individuals who refuse to have an MRI because of claustrophobia. This open MRI system is also up to three times faster than other scanners, therefore the Signa OpenSpeed™ reducing exam time and scheduling issues. In addition, a swing table provides better access and supports up to 500 pounds.
Device Information and Specification
CLINICAL APPLICATION
Whole body
CONFIGURATION
Integrated transmit and receive body coil; 4 channel head array, 8 channel CTL array, 2 channel shoulder array, 3 channel large extremity array, 3 channel small extremity array, 4 channel foot array, 3 channel wrist array, 4 channel breast array
SYNCHRONIZATION
Standard cardiac gating, ECG/peripheral, respiratory gating
PULSE SEQUENCES
Standard: SE, IR, 2D/3D GRE and SPGR, Angiography: 2D/3D TOF, 2D/3D Phase Contrast;; 2D/3D FSE, 2D/3D FGRE and FSPGR, SSFP, FLAIR, EPI, optional: 2D/3D Fiesta, FGRET, Spiral, Tensor
IMAGING MODES
Localizer, single slice, multislice, volume, fast, POMP, multi slab, cine
TR
1.3 to 12000 msec in increments of 1 msec
TE
0.4 to 2000 msec in increments of 1 msec
SINGLE/MULTI SLICE
Simultaneous scan and reconstruction;; 100 images/second with Reflex 100
1cm to 40 cm continuous
2D: 0.8mm - 20mm 3D: 0.1mm - 20mm
1280 x 1024
MEASURING MATRIX
128x512 steps 32 phase//freq.
PIXEL INTENSITY
256 gray levels
0.08 mm; 0.02 mm optional
175 x 85 x 447 cm
MAGNET WEIGHT
8256 kg
H*W*D
530 x 175 x 250 cm
POWER REQUIREMENTS
200 - 480, 3-phase
COOLING SYSTEM TYPE
Liquid helium
0.03 L/hr, holds 300 L
STRENGTH
25 mT/m
5-GAUSS FRINGE FIELD
4.7 m/ 3.8 m
Computerized passive shimming during magnet setup, autoshim per series with automatic table motion to magnet isocenter for each prescription
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• View the DATABASE results for 'Signa OpenSpeed™' (2).Open this link in a new window

 
Further Reading:
  News & More:
MR Surgical Suite, Improving surgical procedure quality (.pdf)
   by www3.gehealthcare.com    
MRI Resources 
Fluorescence - Devices - MRI Reimbursement - Crystallography - Blood Flow Imaging - Functional MRI
 
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MRI is trending to low field magnets :
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