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| | | | | | | Searchterm 'Magnetic Field' was also found in the following services: | | | | |
| | | | | Searchterm 'Magnetic Field' was also found in the following services: | | | | |
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| | | | • View the DATABASE results for 'Eddy Currents' (8).
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| | | | | | | | Searchterm 'Magnetic Field' was also found in the following services: | | | | |
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Inhomogeneity is the degree of lack of homogeneity, for example the fractional deviation of the local magnetic field from the average value of the field. Inhomogeneities of the static magnetic field, produced by the scanner as well as by object susceptibility, is unavoidable in MRI. The large value of gyromagnetic coefficient causes a significant frequency shift even for few parts per million field inhomogeneity, which in turn causes distortions in both geometry and intensity of the MR images.
Manufacturers try to make the magnetic field as homogeneous as possible, especially at the core of the scanner. Even with an ideal magnet, a little inhomogeneity is always left and is caused in addition by the susceptibility of the imaging object.
The geometrical distortion (displacement of the pixel locations) are important e.g., for some cases as stereotactic surgery. Displacements up to 3 to 5 mm have been reported. The second problem is the undesired changes in the intensity or brightness of pixels, which may cause problems in determining different tissues and reduce the maximum achievable image resolution.
Image Guidance
| | | | • View the DATABASE results for 'Inhomogeneity' (21).
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In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
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Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
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In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
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In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
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1977/78: First images could be presented.
A cross section through a finger by Peter Mansfield and Andrew A. Maudsley.
Peter Mansfield also could present the first image through the abdomen.
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In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
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1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
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1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
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In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
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1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH ( fast low angle shot) sequence.
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1988: Schering's MAGNEVIST gets its first approval by the FDA.
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In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
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From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
| | | | | | • View the DATABASE results for 'MRI History' (6).
| | | • View the NEWS results for 'MRI History' (1).
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