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| | | 'Magnetic Resonance Imaging MRI' | |
Result : Searchterm 'Magnetic Resonance Imaging MRI' found in 1 term [] and 9 definitions [], (+ 18 Boolean[] results
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[This entry is marked for removal.]
Hitachi Medical Systems America, Inc. (HMSA), was a major provider of magnetic resonance imaging systems in the United States. Hitachi had more than 2300 installed permanent magnet MR imaging systems worldwide. As a full-line supplier of medical imaging equipment in Japan, Hitachi Medical Corporation (HMC) founded HMSA to provide a direct link to the U.S. marketplace. Altaire™ , the open MR system from Hitachi, extends the family of open MRI products.
In December 2019 Japan's Fujifilm announced the acquisition of Hitachi's diagnostic imaging business for 179 billion yen ($1.63 billion). This includes Hitachi’s CT, MRI, X-ray, and ultrasound imaging operations, also its electronic health record business. Fujifilm expects the deal to close in July 2020 subject to regulatory clearances.
MRI Scanners:
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(NSF) Nephrogenic systemic fibrosis is a rare and highly debilitating disorder that involves extensive thickening and hardening of the skin with fibrotic nodules and plaques.
MRI contrast media have very low side effects, but accumulating data indicate that gadolinium-based contrast agents increase the risk for the development of NSF among patients with severe renal insufficiency or renal dysfunction due to the hepato-renal syndrome or in the perioperative liver transplantation period.
Due to this reason, gadolinium contrast agents are now considered contraindicated in patients with an estimated glomerular filtration rate fewer than 30 mL/min/1.73m 2.
In these patients, avoid use of gadolinium-based contrast agents unless the diagnostic information is essential and not available with non-contrast enhanced magnetic resonance imaging ( MRI).
Recognized or possibly associated factors for NSF:
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high dose of erythropoietin;
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high serum phosphate levels;
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high serum calcium levels;
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major surgery, infection, vascular event;
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history of hypothyroidism;
When administering a gadolinium-based contrast agent, do not exceed the recommended dose and allow a sufficient period of time for elimination of the contrast medium from the body prior to any readminstration. Screen all patients for renal dysfunction by obtaining a history and/or laboratory tests.
See also Contrast Medium, Adverse Reaction, MRI Risks, MRI Safety, Ionic Intravenous Contrast Agents, Nonionic Intravenous Contrast Agents, and Contraindications.
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ABLAVAR™ (formerly named Vasovist™) is a blood pool agent for magnetic resonance angiography ( MRA), which opens new medical imaging possibilities in the evaluation of aortoiliac occlusive disease (AIOD) in patients with suspected peripheral vascular disease.
ABLAVAR™ binds reversibly to blood albumin, providing imaging with high spatial resolution up to 1 hour after injection, due to its high relaxivity and to the long lasting increased signal intensity of blood.
As with other contrast media: the possibility of serious or life-threatening anaphylactic or anaphylactoid reactions, including cardiovascular, respiratory and/or cutaneous manifestations, should always be considered.
WARNING: NEPHROGENIC SYSTEMIC FIBROSIS
Gadolinium-based contrast agents increase the risk for nephrogenic systemic fibrosis (NSF) in patients with acute or chronic severe renal insufficiency (glomerular filtration rate less than 30 mL/min/1.73m 2), or acute renal insufficiency of any severity due to the hepato-renal syndrome or in the perioperative liver transplantation period.
See also Cardiovascular Imaging, Adverse Reaction, Molecular Imaging, and MRI Safety.
Drug Information and Specification
NAME OF COMPOUND
Diphenylcyclohexyl phosphodiester-Gd-DTPA, gadofosveset trisodium, MS-325
T1, predominantly positive enhancement
20-45 mmol-1sec-1, Bo=0,47T
PHARMACOKINETIC
Intravascular
CONCENTRATION
244 mg/mL, 0.25mmol/mL
DOSAGE
0.12 mL/kg, 0.03 mmol/kg
DEVELOPMENT STAGE
FDA approved
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING
PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT STAGE
DISTRIBUTOR
USA, Canada, Australia
ABLAVAR™
Approved
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