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| | | 'Magnetic Resonance Spectroscopy' | |
Result : Searchterm 'Magnetic Resonance Spectroscopy' found in 1 term [] and 7 definitions [], (+ 13 Boolean[] results
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FDA cleared and CE Mark 2011.
The Biograph mMR has a fully-integrated design for simultaneous PET/MRI imaging. The dedicated hardware includes solid-state, avalanche photodiode PET detector and adapted, PET-compatible MR coils.
The possibility of truly simultaneous operation allows the acquisition of several magnetic resonance imaging ( MRI) sequences during the positron emission tomography (PET) scan, without increasing the examination time.
See also Hybrid Imaging.
Device Information and Specification
CLINICAL APPLICATION
Whole Body
CONFIGURATION
Simultaneous PET/MRI
26 cm (typical overlap 23%)
A-P 45, R-L 50, H-F 50 cm
PET RING DIAMETER
65.6 cm
PATIENT SCAN RANGE
199 cm
HORIZONTAL SPEED
200 mmsec
PET DETECTOR
Solid state, 4032 avalanche photo diodes
DETECTOR SCINTILLATION MATERIAL
LSO, 28672 crystals
CRYSTAL SIZE
4 x 4 x 20 mm
DIMENSION H*W*D (gantry included)
335 x 230 x 242 cm (finshed covers)
COOLING SYSTEM
PET system: water; MRI system: water
Aautomatic, patient specific shim; active shim 3 linear and 5 non-linear channels (seond order)
POWER REQUIREMENTS
380 / 400 / 420 / 440 / 460 / 480 V, 3-phase + ground; Total system 110kW
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Brain imaging, magnetic resonance imaging of the head or skull, cranial magnetic resonance tomography (MRT), neurological MRI - they describe all the same radiological imaging technique for medical diagnostic.
Magnetic resonance imaging of the human brain includes the anatomic description and the detection of lesions. Special techniques like diffusion weighted imaging, functional magnetic resonance imaging ( fMRI) and spectroscopy provide also information about the function and chemical metabolites of the brain.
MRI provides detailed pictures of brain and nerve tissues in multiple planes without obstruction by overlying bones. Brain MRI is the procedure of choice for most brain disorders. It provides clear images of the brainstem and posterior brain, which are difficult to view on a CT scan. It is also useful for the diagnosis of demyelinating disorders (disorders such as multiple sclerosis (MS) that cause destruction of the myelin sheath of the nerve).
With this noninvasive procedure also the evaluation of blood flow and the flow of cerebrospinal fluid (CSF) is possible. Different MRA methods, also without contrast agents can show a venous or arterial angiogram. MRI can distinguish tumors, inflammatory lesions, and other pathologies from the normal brain anatomy. However, MRI scans are also used instead other methods to avoid the dangers of interventional procedures like angiography (DSA - digital subtraction angiography) as well as of repeated exposure to radiation as required for computed tomography (CT) and other X-ray examinations.
A ( birdcage) bird cage coil achieves uniform excitation and reception and is commonly used to study the brain. Usually a brain MRI procedure includes FLAIR, T2 weighted and T1 weighted sequences in two or three planes. See also Fetal MRI, Fluid Attenuation Inversion Recovery ( FLAIR), Perfusion Imaging and High Field MRI. See also Arterial Spin Labeling. | | | | | | | | • View the DATABASE results for 'Brain MRI' (14).
| | | • View the NEWS results for 'Brain MRI' (32).
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MRI Reveals Significant Brain Abnormalities Post-COVID Monday, 21 November 2022 by neurosciencenews.com | | |
Combining genetics and brain MRI can aid in predicting chances of Alzheimer's disease Wednesday, 29 June 2022 by www.sciencedaily.com | | |
Roundup: How Even Mild COVID Can Affect the Brain; This Many Daily Steps Improves Longevity; and More Friday, 11 March 2022 by baptisthealth.net | | |
A low-cost and shielding-free ultra-low-field brain MRI scanner Tuesday, 14 December 2021 by www.nature.com | | |
Large International Study Reveals Spectrum of COVID-19 Brain Complications Tuesday, 9 November 2021 by www.itnonline.com | | |
Brain MRI-Based Subtypes of MS Predict Disability Progression, Treatment Response Thursday, 13 May 2021 by www.neurologyadvisor.com | | |
New MRI method improves detection of disease changes in the brain's network Thursday, 11 June 2020 by www.compute.dtu.dk | | |
New NeuroCOVIDÂť Classification System Uses MRI to Categorize Patients Friday, 12 June 2020 by www.diagnosticimaging.com | | |
New MRI technique can 'see' molecular changes in the brain Thursday, 5 September 2019 by medicalxpress.com | | |
Talking therapy or medication for depression: Brain scan may help suggest better treatment Monday, 27 March 2017 by www.newsnation.in | | |
MRI identifies brain abnormalities in chronic fatigue syndrome patients Wednesday, 29 October 2014 by www.eurekalert.org | | |
MRIs Useful in Tracking Depression in MS Patients Tuesday, 1 July 2014 by www.hcplive.com | | |
Contrast agent linked with brain abnormalities on MRI Tuesday, 17 December 2013 by www.sciencecodex.com | | |
MRIs Reveal Signs of Brain Injuries Not Seen in CT Scans Tuesday, 18 December 2012 by www.sciencedaily.com | | |
Iron Deposits in the Brain May Be Early Indicator of MS Wednesday, 13 November 2013 by www.healthline.com | | |
Migraine Sufferers Have Thicker Brain Cortex Tuesday, 20 November 2007 by www.medicalnewstoday.com |
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For the wide uses of NMR spectroscopy (from mineralogy to medicine) there is a variety of different spectroscopic imaging techniques available.
A short listing of the most frequent variations:
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'Two-dimensional NMR Spectroscopy' (2D NMR) is based on pulse spectroscopy. This technique is mostly used for the study of chemical interactions accompanied by magnetization transfer. Examples for more diversified spectroscopy techniques are based on homonuclear (COSY, TOCSY, 2D-INADEQUATE, NOESY, ROESY) or heteronuclear correlation (HSQC, HMQC, HMBC).
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'Solid State NMR Spectroscopy' analyzes samples with little or no molecular mobility. Dipolar coupling and chemical shift anisotropy are the dominating nuclear physical effects here. Used for example in pharmaceutical analysis.
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'Solution State NMR Spectroscopy' is a technique to analyze the structure of samples with a high degree of molecular mobility as polymers, proteins, nucleic acids etc.
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Inert hyperpolarized gases are under development for imaging air spaces, including those in the lungs. Because they mostly contain air and water, lungs are difficult organs to image.
These ventilation agents (gases) have potential in lung imaging and are currently used in studies of the pulmonary ventilation:
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aerosolized gadolinium-DTPA
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hyperpolarized gases (xenon-129, helium-3)
Specific isotopes of inert gases can be hyperpolarized. Hyperpolarized is a state in which almost all of the atoms nuclei are spinning in the same direction. Once the nuclei in the isotope 3He have been hyperpolarized using a laser, they remain in this state for several days.
The inert, hyperpolarized gas can then be used in a lung imaging study, where the high concentration of polarized nuclei provides a sharp contrast in MRI. The technique is already being developed with a view to commercialization by Magnetic Imaging Technologies in Durham, North Carolina. According to the company, existing MRI equipment can be used with a few minor modifications, along with a gas polarizer. The technique could provide early detection and monitoring of pulmonary disease.
Hyperpolarized 129Xe can also be used as a magnetic resonance tracer because of its MR-enhanced sensitivity combined with its high solubility.
This isotope differs from 3He in that it can dissolve in the blood. Strong enhancement of the nuclear spin polarization of xenon in the gas phase can be achieved by optical pumping of rubidium and subsequent spin-exchange with the xenon nuclei.
This technique can increase the magnetic resonance signal of xenon by five orders of magnitude, thus allowing NMR detection of xenon in very low concentration. MR spectroscopy and imaging of optically polarized xenon shows considerable potential for medical applications (see also back projection imaging).
Nycomed Amersham anticipated the market for inert gases in pulmonary imaging. The company obtained an exclusive license for the use of helium (He) and xenon (Xe) as MRI contrast agents. Currently, the US FDA has not yet approved the commercial distribution of inert gas imaging equipment, because the technique is still undergoing trials. | | | | • View the DATABASE results for 'Ventilation Agents' (3).
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