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Lantheus Medical Imaging, Inc.
 
www.radiopharm.com Lantheus Medical Imaging is a worldwide leader in medical imaging, with headquarters in North Billerica, Massachusetts, and nearly 700 employees worldwide with offices in Puerto Rico, Canada, and Australia.
The product portfolio includes ABLAVAR™ (gadofosveset trisodium) a blood pool contrast agent for magnetic resonance angiography MRA, Cardiolite® (Kit for the preparation of Technetium Tc99m Sestamibi), a cardiac perfusion imaging agent and DEFINITY® Vial for (Perflutren Lipid Microsphere) injectable suspension, the leading cardiac ultrasound contrast agent in the US.

MRI Contrast Agents:
Contact Information
MAIL
Lantheus Medical Imaging
Bldg. 200-2, 331 Treble Cove Rd.
N. Billerica, MA 01862
USA
PHONE
+1-800-362-2668
FAX
+1-978-436-7501
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Searchterm 'Mass' was also found in the following services: 
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Radiology  (29) Open this link in a new windowUltrasound  (15) Open this link in a new window
MRI History
 
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Sir Joseph Larmor (1857-1942) developed the equation that the angular frequency of precession of the nuclear spins being proportional to the strength of the magnetic field. [Larmor relationship]
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In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
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Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
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In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
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In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
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In 1975, Richard Ernst introduced 2D NMR using phase and frequency encoding, and the Fourier Transform. Instead of Paul Lauterbur's back-projection, he timely switched magnetic field gradients ('NMR Fourier Zeugmatography'). [This basic reconstruction method is the basis of current MRI techniques.]
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1977/78: First images could be presented. A cross section through a finger by Peter Mansfield and Andrew A. Maudsley. Peter Mansfield also could present the first image through the abdomen.
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In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
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1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
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1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
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In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
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In 1984, FONAR Corporation receives FDA approval for its first MRI scanner.
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1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH (fast low angle shot) sequence.
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1988: Schering's MAGNEVIST gets its first approval by the FDA.
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In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
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From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
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Images, Movies, Sliders:
 Cardiac Infarct Short Axis Cine Overview  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 
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• View the NEWS results for 'MRI History' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
Fonar Our History
   by www.fonar.com    
  News & More:
Scientists win Nobels for work on MRI
Tuesday, 10 June 2003   by usatoday30.usatoday.com    
2001 Lemelson-MIT Lifetime Achievement Award Winner
   by web.mit.edu    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
MRI Resources 
Homepages - Stimulator pool - Mobile MRI Rental - Raman Spectroscopy - Chemistry - Health
 
Magnetic ForcesMRI Resource Directory:
 - MRI Accidents -
 
Forces can result from the interaction of magnetic fields. Pulsed magnetic field gradients can interact with the main magnetic field during the MRI scan, to produce acoustic noise through the gradient coil.
Magnetic fields attract ferromagnetic objects with forces, which can be a lethal danger if one is hit by an unrestrained object in flight. One could also be trapped between the magnet and a large unrestrained ferromagnetic object or the object could damage the MRI machine.
Access control and personnel awareness are the best preventions of such accidents. The attraction mechanism for ferromagnetic objects is that the magnetic field magnetizes the iron. This induced magnetization reacts with the gradient of the magnetic field to produce an attraction toward the strongest area of the field. The details of this interaction are very dependent on the shape and composition of the attracted object. There is a very rapid increase of force as one approaches a magnet. There is also a torque or twisting force on objects, e.g. a long cylinder (such as a pen or an intracranial aneurysm clip) will tend to align along the magnet's field lines. The torque increases with field strength while the attraction increases with field gradient.
Depending on the magnetic saturation of the object, attraction is roughly proportional to object mass. Motion of conducting objects in magnetic fields can induce eddy currents that can have the effect of opposing the motion.

See also Duty Cycle.

See also the related poll result: 'Most outages of your scanning system are caused by failure of'
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• View the DATABASE results for 'Magnetic Forces' (4).Open this link in a new window

 
Further Reading:
  Basics:
How strong are magnets?
   by my.execpc.com    
Magnetic Field of the Strongest Magnet
2003   by hypertextbook.com    
  News & More:
Imaging chain faces regulators after inmate, guard get stuck to MRI machine
Friday, 1 December 2023   by healthimaging.com    
Measuring magnetic force field distributions in microfluidic devices: Experimental and numerical approaches
Saturday, 2 December 2023   by analyticalsciencejournals.onlinelibrary.wiley.com    
Two stuck to MRI machine for 4 hrs
Tuesday, 11 November 2014   by www.mumbaimirror.com    
New imaging project for new applications in cancer diagnostics
Monday, 27 March 2017   by www.news-medical.net    
Searchterm 'Mass' was also found in the following services: 
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News  (43)  Resources  (48)  Forum  (3)  
 
ONI Medical Systems, Inc.MRI Resource Directory:
 - Manufacturers -
 
www.onicorp.com Founded in June 1997, ONI was a privately held company headquartered in Wilmington, Massachusetts. ONI was focused on addressing the new healthcare economics by delivering the next generation of MRI machines: high field, low cost dedicated purpose systems. The company's first offering was the OrthOne™. Further developments lead to the MSK Extreme™, a 1.0 Tesla dedicated purpose MR system with v-SPEC™ Technology and DICOM Conformance for extremity applications.
In October 2009 GE Healthcare bought ONI Medical Systems for US$ 17 Billion.

MRI Scanners:

1.0T:
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Radiology  (29) Open this link in a new windowUltrasound  (15) Open this link in a new window
Oral Contrast AgentsForum -
related threadsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
A limitation of abdominal MRI can be the assessment of malignancies by difficulties to distinguish bowel from other organs or malignant masses. The use of oral contrast agents can reduce this problem. Properties of an ideal oral contrast agent are little or no absorption by the stomach or intestines, complete excretion, no motion or susceptibility artifacts, and uniform marking of the GI tract.
Gastrointestinal MRI contrast agents are divided in materials with bright appearance or dark appearance. The choice of a negative or a positive oral contrast agent depends on the specific problem or the pulse sequence.

See also Positive Oral Contrast Agents, Negative Oral Contrast Agents, Gastrointestinal Diamagnetic Contrast Agents, Gastrointestinal Paramagnetic Contrast Agents and Gastrointestinal Superparamagnetic Contrast Agents.

See also the related poll result: 'The development of contrast agents in MRI is'
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Further Reading:
  News & More:
Usefulness of MR Imaging for Diseases of the Small Intestine: Comparison with CT
2000   by www.ncbi.nlm.nih.gov    
Nottingham scientists exploit MRI technology to assist in the treatment of IBS
Thursday, 9 January 2014   by www.news-medical.net    
MRI Resources 
Artifacts - Safety Products - Jobs pool - Most Wanted - Shoulder MRI - Case Studies
 
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