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(ASL) A MR image can be sensitized to the effect of inflowing blood spins if those spins are in a different magnetic state to that of the static tissue. Techniques known as ASL techniques uses this idea by magnetically labeling blood flowing into the slices of interest. Contrast agents are not required for these techniques. This perfusion measurement is completely noninvasive.
Blood flowing into the imaging slice exchanges with tissue water, altering the tissue magnetization. A perfusion-weighted image can be generated by the subtraction of an image in which inflowing spins have been labeled from an image in which spin labeling has not been performed.
Quantitative perfusion maps can be calculated if other para meters (such as tissue T1 and the efficiency of spin labeling) also are measured. | | | | | | | | | Further Reading: | News & More:
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| | | | • View the DATABASE results for 'B0' (41).
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A bolus is a rapid infusion of high dose contrast agent. Dynamic and accumulation phase imaging can be performed after bolus injection. Since the transit time of the bolus through the tissue is only a few seconds, high temporal resolution imaging can be required to obtain sequential images during the wash in and wash out of the contrast material and, therefore, resolve the first pass of the tracer.
For the same injected dose of contrast agent the injection rate (and, consequently, the total injected volume) modifies the bolus peak profile. Increasing the injection rate produces a sharpening of the peak
(Cmax increase, Tmax decrease, peak length decrease). At a
low injection rate, the first pass presents a plateau form.
Substantial changes in the gadolinium concentrations during signal acquisition induce artifacts. Furthermore, the haemodynamic
para meters ( cardiac output, blood pressure) influence
the bolus profile.
The characteristics of gadolinium agents are favorable in the early bolus
phase, whereas the advantages of large complexes (e.g. blood pool agents) and ultrasmall superparamagnetic iron oxide ( USPIO) are most evident in the distribution phase. | | | | | | • View the DATABASE results for 'Bolus Injection' (9).
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Device Information and Specification
CLINICAL APPLICATION
Dedicated extremity
SE, GE, IR, STIR, FSE, 3D CE, GE-STIR, 3D GE, ME, TME, HSE
IMAGING MODES
Single, multislice, volume study, fast scan, multi slab
2D: 2 mm - 10 mm;
3D: 0.6 mm - 10 mm
4,096 gray lvls, 256 lvls in 3D
POWER REQUIREMENTS
100/110/200/220/230/240
| | | | • View the DATABASE results for 'C-SCAN™' (4).
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Cardiovascular MR imaging includes the complete anatomical display of the heart with CINE imaging of all phases of the heartbeat. Ultrafast techniques make breath hold three-dimensional coverage of the heart in different cardiac axes feasible. Cardiac MRI provides reliable anatomical and functional assessment of the heart and evaluation of myocardial viability and coronary artery disease by a noninvasive diagnostic imaging technique.
Cardiovascular MRI offers potential advantages over radioisotopic techniques because it provides superior spatial resolution, does not use ionizing radiation, has no imaging orientations constraints and contrast resolution better than echocardiography. It also offers direct visualization and characterization of atherosclerotic plaques and diseased vessel walls and surrounding tissues in cardiovascular research.
MRI perfusion approaches measure the alteration of regional myocardial magnetic properties after the intravenous injection of contrast agents and assess the extent of injury after a myocardial infarction and the presence of myocardial viability with a technique based on late enhancement. Extracellular MRI contrast agents, like Gd-DTPA, accumulate only in irreversibly damaged myocardium after a time period of at least 10 minutes.
This type of patients may also have an implanted cardiac stent, bypass or a cardiac pacemaker and special caution should be observed on the MRI safety and the contraindications. While a number of coronary stents have been tested and reported to be MRI compatible, coronary stents must be assessed on an individual basis, with the medical team weighing the risks and benefits of the MRI procedure.
Cardiac MRI overview:
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Calculation of ventricular volume, myocardial mass and wall thickness
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Functional parameters
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Description of a stenosis or aneurysma
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Anatomical display of the heart, vessels and the surrounding tissue
Cardiovascular MRI has become one of the most effective noninvasive imaging techniques for almost all groups of heart and vascular disease. | | | | | | • View the DATABASE results for 'Cardiovascular Imaging' (18).
| | | • View the NEWS results for 'Cardiovascular Imaging' (6).
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