Special
imaging primarily means advanced
MRI techniques used for qualitative and quantitative measurement of biological metabolism as e.g.,
spectroscopy,
perfusion imaging (PWI,
ASL),
diffusion weighted imaging (
DWI,
DTI, DTT) and
brain function (
BOLD,
fMRI). This physiological
magnetic resonance techniques offer insights into
brain structure, function, and metabolism.
Spectroscopy provides functional information related to identification and quantification of e.g.
brain metabolites.
MR
perfusion imaging has applications in stroke, trauma, and
brain neoplasm.
MRI provides the high spatial and
temporal resolution needed to measure blood
flow to the
brain.
arterial spin labeling techniques utilize the intrinsic protons of blood and
brain tissue, labeled by special preparation pulses, rather than exogenous tracers injected into the blood.
MR
diffusion tensor imaging characterizes the ability of water to spread across the
brain in different directions.
Diffusion parallel to nerve fibers has been shown to be greater than
diffusion in the perpendicular direction. This provides a tool to study in vivo fiber connectivity in
brain MRI.
FMRI allows the detection of a functional activation in the
brain because cortical activity is intimately related to local metabolism changes.
See also
Diffusion Tensor Tractography.