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Result : Searchterm 'Radio Frequency' found in 12 terms [] and 63 definitions []
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The subacute risks and side effects of magnetic and RF fields (for patients and staff) have been intensively examined for a long time, but there have been no long-term studies following persons who have been exposed to the static magnetic fields used in MRI. However, no permanent hazardous effects of a static magnetic field exposure upon human beings have yet been demonstrated.
Temporary possible side effects of high magnetic and RF fields:
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Varying magnetic fields can induce so-called magnetic phosphenes that occur when an individual is subject to rapid changes of 2-5 T/s, which can produce a flashing sensation in the eyes. This temporary side effect does not seem to damage the eyes. Static field strengths used for clinical MRI examinations vary between 0.2 and 3.0 tesla;; field changes during the MRI scan vary in the dimension of mT/s. Experimental imaging units can use higher field strengths of up to 14.0 T, which are not approved for human use.
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The Radio frequency pulses mainly produce heat, which is absorbed by the body tissue. If the power of the RF radiation is very high, the patient may be heated too much. To avoid this heating, the limit of RF exposure in MRI is up to the maximum specific absorption rate (SAR) of 4 W/kg whole body weight (can be different from country to country). For MRI safety reasons, the MRI machine starts no sequence, if the SAR limit is exceeded.
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Very high static magnetic fields are needed to reduce the conductivity of nerves perceptibly. Augmentation of T waves is observed at fields used in standard imaging but this side effect in MRI is completely reversible upon removal from the magnet. Cardiac arrhythmia threshold is typically set to 7-10 tesla. The magnetohydrodynamic effect, which results from a voltage occurring across a vessel in a magnetic field and percolated by a saline solution such as blood, is irrelevant at the field strengths used.
The results of some animal and cellular studies suggest the possibility that electromagnetic fields may act as co-carcinogens or tumor promoters, but the data are inconclusive.
Up to 45 tesla, no important effects on enzyme systems have been observed. Neither changes in enzyme kinetics, nor orientation changes in macromolecules have been conclusively demonstrated.
There are some publications associating an increase in the incidence of leukemia with the location of buildings close to high-current power lines with extremely low-frequency (ELF) electromagnetic radiation of 50-60 Hz, and industrial exposure to electric and magnetic fields but a transposition of such effects to MRI or MRS seems unlikely.
Under consideration of the MRI safety guidelines, real dangers or risks of an exposure with common MRI field strengths up to 3 tesla as well as the RF exposure during the MRI scan, are not to be expected.
For more MRI safety information see also Nerve Conductivity,
Contraindications, Pregnancy
and Specific Absorption Rate.
See also the related poll result: ' In 2010 your scanner will probably work with a field strength of' | | | | • For this and other aspects of MRI safety see our InfoSheet about MRI Safety. | | | • Patient-related information is collected in our MRI Patient Information.
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( MRI) Magnetic resonance imaging is a noninvasive medical imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field and body tissue to obtain images of slices/planes from inside the body. These magnets generate fields from approx. 2000 times up to 30000 times stronger than that of the Earth. The use of nuclear magnetic resonance principles produces extremely detailed pictures of the body tissue without the need for x-ray exposure and gives diagnostic information of various organs.
Measured are mobile hydrogen nuclei (protons are the hydrogen atoms of water, the 'H' in H 20), the majority of elements in the body. Only a small part of them contribute to the measured signal, caused by their different alignment in the magnetic field. Protons are capable of absorbing energy if exposed to short radio wave pulses (electromagnetic energy) at their resonance frequency. After the absorption of this energy, the nuclei release this energy so that they return to their initial state of equilibrium.
This transmission of energy by the nuclei as they return to their initial state is what is observed as the MRI signal. The subtle differing characteristic of that signal from different tissues combined with complex mathematical formulas analyzed on modern computers is what enables MRI imaging to distinguish between various organs. Any imaging plane, or slice, can be projected, and then stored or printed.
The measured signal intensity depends jointly on the spin density and the relaxation times ( T1 time and T2 time), with their relative importance depending on the particular imaging technique and choice of interpulse times. Any motion such as blood flow, respiration, etc. also affects the image brightness.
Magnetic resonance imaging is particularly sensitive in assessing anatomical structures, organs and soft tissues for the detection and diagnosis of a broad range of pathological conditions. MRI pictures can provide contrast between benign and pathological tissues and may be used to stage cancers as well as to evaluate the response to treatment of malignancies. The need for biopsy or exploratory surgery can be eliminated in some cases, and can result in earlier diagnosis of many diseases. See also MRI History and Functional Magnetic Resonance Imaging (fMRI). | | | | | | • View the DATABASE results for 'Magnetic Resonance Imaging MRI' (9).
| | | • View the NEWS results for 'Magnetic Resonance Imaging MRI' (222).
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(MT) Magnetization Transfer was accidentally discovered by Wolff and Balaban in 1989. Conventional MRI is based on the differences in T1, T2 and the proton density (water content and the mobility of water molecules) in tissue; it relies primarily on free (bulk) water protons. The T2 relaxation times are greater than 10 ms and detectable. The T2 relaxation times of protons associated with macromolecules are less then 1 ms and not detectable in MRI.
Magnetization Transfer Imaging (MTI) is based on the magnetization interaction (through dipolar and/or chemical exchange) between bulk water protons and macromolecular protons. By applying an off resonance radio frequency pulse to the macromolecular protons, the saturation of these protons is then transferred to the bulk water protons. The result is a decrease in signal (the net magnetization of visible protons is reduced), depending on the magnitude of MT between tissue macromolecules and bulk water. With MTI, the presence or absence of macromolecules (e.g. in membranes, brain tissue) can be seen.
The magnetization transfer ratio (MTR) is the difference in signal intensity with or without MT.
See also Magnetization Transfer Contrast. | | | | • View the DATABASE results for 'Magnetization Transfer' (7).
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(MTC) This MRI method increases the contrast by removing a portion of the total signal in tissue. An off resonance radio frequency (RF) pulse saturates macromolecular protons to make them invisible (caused by their ultra-short T2* relaxation times). The MRI signal from semi-solid tissue like brain parenchyma is reduced, and the signal from a more fluid component like blood is retained.
E.g., saturation of broad spectral lines may produce decreases in intensity of lines not directly saturated, through exchange of magnetization between the corresponding states; more closely coupled states will show a greater resulting intensity change.
Magnetization transfer techniques make demyelinated brain or spine lesions (as seen e.g. in multiple sclerosis) better visible on T2 weighted images as well as on gadolinium contrast enhanced T1 weighted images.
Off resonance makes use of a selection gradient during an off resonance MTC pulse. The gradient has a negative offset frequency on the arterial side of the imaging volume (caudally more off resonant and cranially less off resonant). The net effect of this type of pulse is that the arterial blood outside the imaging volume will retain more of its longitudinal magnetization, with more vascular signal when it enters the imaging volume. Off resonance MTC saturates the venous blood, leaving the arterial blood untouched.
On resonance has no effect on the free water pool but will saturate the bound water pool and is the difference in T2 between the pools. Special binomial pulses are transmitted causing the magnetization of the free protons to remain unchanged. The z-magnetization returns to its original value. The spins of the bound pool with a short T2 experience decay, resulting in a destroyed magnetization after the on resonance pulse.
See also Magnetization Transfer. | | | | • View the DATABASE results for 'Magnetization Transfer Contrast' (5).
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Pulse sequences, designed to be insensitive to flow, e.g. at every even echo, a spin echo sequence is not flow sensitive. Velocity compensation is achieved by using gradients, which are either symmetrical around a 180° pulse and switched on twice as is the case for motion compensated spin echo pulse sequences, or two antisymmetrical gradient lobes without 180° pulse, which is the way to produce a velocity compensated gradient echo pulse sequence.
The signal of the second echo (and all other even echoes) is independent of the velocity of the object. Thus, velocity-based motion effects stemming from the entire voxel or from spins within a voxel ( intravoxel incoherent motion) are suppressed with such pulse sequences.
If higher order motion is relevant, as it may be in turbulent jets across valves, acceleration and jerk effects can also be compensated for by the use of appropriate combinations of gradient- and radio frequency pulses.
With the increasingly stronger gradients, echo times in MR systems can be shortened to the point at which effects other than velocity effects hardly ever become relevant. | | | | • View the DATABASE results for 'Motion Compensation Pulse Sequences' (2).
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