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Result : Searchterm 'Safety' found in 2 terms [] and 55 definitions []
| previous 16 - 20 (of 57) nextResult Pages : [1] [2 3 4 5 6 7 8 9 10 11 12] | | | | Searchterm 'Safety' was also found in the following services: | | | | |
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The interactions between the most tested heart valve prostheses and the magnetic field of MRI devices are of no significance. However, there are many different types of heart valve prostheses and in the particular case their MRI safety should be checked.
Prosthetic heart valves, depending on the type and the material, are not necessarily considered to be dangerous in fields up to 3T. Patients should not undergo high field MRI examinations if valve dehiscence is clinically suspected. | | | | • For this and other aspects of MRI safety see our InfoSheet about MRI Safety. | | | • Patient-related information is collected in our MRI Patient Information.
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ABLAVAR™ (formerly named Vasovist™) is a blood pool agent for magnetic resonance angiography ( MRA), which opens new medical imaging possibilities in the evaluation of aortoiliac occlusive disease (AIOD) in patients with suspected peripheral vascular disease.
ABLAVAR™ binds reversibly to blood albumin, providing imaging with high spatial resolution up to 1 hour after injection, due to its high relaxivity and to the long lasting increased signal intensity of blood.
As with other contrast media: the possibility of serious or life-threatening anaphylactic or anaphylactoid reactions, including cardiovascular, respiratory and/or cutaneous manifestations, should always be considered.
WARNING: NEPHROGENIC SYSTEMIC FIBROSIS
Gadolinium-based contrast agents increase the risk for nephrogenic systemic fibrosis (NSF) in patients with acute or chronic severe renal insufficiency (glomerular filtration rate less than 30 mL/min/1.73m 2), or acute renal insufficiency of any severity due to the hepato-renal syndrome or in the perioperative liver transplantation period.
See also Cardiovascular Imaging, Adverse Reaction, Molecular Imaging, and MRI Safety.
Drug Information and Specification
NAME OF COMPOUND
Diphenylcyclohexyl phosphodiester-Gd-DTPA, gadofosveset trisodium, MS-325
T1, predominantly positive enhancement
20-45 mmol-1sec-1, Bo=0,47T
PHARMACOKINETIC
Intravascular
CONCENTRATION
244 mg/mL, 0.25mmol/mL
DOSAGE
0.12 mL/kg, 0.03 mmol/kg
DEVELOPMENT STAGE
FDA approved
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING
PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT STAGE
DISTRIBUTOR
USA, Canada, Australia
ABLAVAR™
Approved
| | | | • View the DATABASE results for 'ABLAVAR™' (3).
| | | • View the NEWS results for 'ABLAVAR™' (1).
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| | | | • View the DATABASE results for 'Absorbed Dose' (2).
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| | | Searchterm 'Safety' was also found in the following services: | | | | |
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| | | | | | | | | • View the DATABASE results for 'Adverse Reaction' (8).
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The brain tissue is provided with a tight endothelial layer on vessels that acts as a filter for substances that reach the brain through the blood stream. This filter is called the blood brain barrier.
The blood brain barrier is responsible for the absence of contrast agent enhancement in normal brain tissue after administration of the iodinated or paramagnetic contrast media used in brain MRI and computed tomography (CT) diagnostic. The absence of contrast uptake in normal tissue provides the basis for differentiation from pathological brain tissue, which is conversely characterized by a disruption of the blood brain barrier.
See also Contrast Enhanced MRI, MRI Safety, Adverse Reaction. | | | | | | • View the DATABASE results for 'Blood Brain Barrier' (7).
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