MR imaging technique in which a set of projection profiles of the body is obtained by observing MR signals in the presence of a suitable corresponding set of magnetic field gradients. Images can then be reconstructed using techniques analogous to those used in conventional computed tomography (CT), such as filtered back projection. It can be used for volume imaging or, with plane selection techniques, for sequential plane imaging.
Imaging techniques in which NMR signals are gathered from the whole object volume to be imaged at once, with appropriate encoding pulse RF and gradientsequences to encode positions of the spins. Many sequential plane imaging techniques can be generalized to volume imaging, at least in principle. Advantages include potential improvement in signal to noise ratio by including signal from the whole volume at once; disadvantages include a bigger computational task for image reconstruction and longer image acquisition times (although the entire volume can be imaged from the one set of data). Also called simultaneous volume imaging.
(TOF) The time of flight angiography is used for the imaging of vessels. Usually the sequence type is a gradient echosequences with short TR, acquired with slices perpendicular to the direction of blood flow.
The source of diverse flow effects is the difference between the unsaturated and presaturated spins and creates a bright vascular image without the invasive use of contrast media. Flowing blood moves unsaturated spins from outside the slice into the imagingplane. These completely relaxed spins have full equilibriummagnetization and produce (when entering the imagingplane) a much higher signal than stationary spins if a gradient echo sequence is generated. This flow related enhancement is also referred to as entry slice phenomenon, or inflow enhancement.
Performing a presaturationslab on one side parallel to the slice can selectively destroy the MR signal from the in-flowing blood from this side of the slice. This allows the technique to be flow direction sensitive and to separate arteriograms or venograms. When the local magnetization of moving blood is selectively altered in a region, e.g. by selective excitation, it carries the altered magnetization with it when it moves, thus tagging the selected region for times on the order of the relaxation times.
For maximum flow signal, a complete new part of blood has to enter the slice every repetition (TR) period, which makes time of flight angiography sensitive to flow-velocity. The choice of TR and slice thickness should be appropriate to the expected flow-velocities because even small changes in slice thickness influences the performance of the TOF sequence.
The use of sequential2 dimensional Fourier transformation (2DFT) slices, 3DFT slabs, or multiple 3D slabs (chunks) are depending on the coverage required and the range of flow-velocities.
3D TOF MRA is routinely used for evaluating the Circle of Willis.