A pixel is a picture element (pix, abbreviation of pictures + element). Tomographic images are composed of several pixels.
The corresponding size of the pixel may be smaller than the actual spatial resolution. Pixels do not have a fixed size; their diameters are generally measured in micrometers (microns). Although the pixel is not a unit of measurement itself, pixels are often used to measure the resolution (or sharpness) of images. As a hypothetical example, a 600 x 1000 pixel image has 4 times the pixel density and is thus 4 times sharper than a 300 x 500 pixel image, assuming the two images have the same physical size.

(RFOV) A different field of view (the scanned region) in the frequency and phase encoding directions that means the data acquisition with fewer measurement lines. Because there are fewer rows than columns, a rectangular image is obtained. To reduce the FOV in phase encoding direction (foldover direction) saves scan time by decreasing signal but invariable spatial resolution.
Also called HFI or undersampling.

If the scanned object is oval, e.g. head or abdomen, a rectangular FOV is an easy to use scan parameter to reduce the scan time without loss of resolution.

See Spatial Resolution.

Liver imaging with gadolinium contrast enhanced MRI is sometimes not sufficient for a reliable diagnosis of liver lesions. For this reasons, special liver Contrast agents that are targeted to the reticuloendothelial system (RES), have been developed to improve both detection and characterization of liver and spleen lesions. Reticuloendothelial Contrast Agents, as e.g. superparamagnetic iron oxides (SPIO), are taken up by healthy liver tissue but not tumors.
These RES targeted contrast agents provide a prolonged imaging window and enough time for high spatial resolution or multiple breath hold images. Reticuloendothelial contrast agents have an increased sensitivity for the detection of small liver lesions (e.g., metastases), compared with gadolinium enhanced MRI and spiral CT. At higher field strengths with an increased signal to noise ratio the susceptibility effect with iron oxide particles may be enhanced.
Other new agents (Gadobenate Dimeglumine, Gadoxetic Acid) have both an initial extracellular circulation and a delayed liver-specific uptake. Since a considerable part of these contrast agents is excreted in the bile, functional biliary imaging can diagnose biliary anomalies, postoperative bile leaks, and anastomotic strictures. Other agents, such as liposomes (with encapsulated Gd-DTPA) or DOTA complexes are in different development stages.

See also Hepatobiliary Contrast Agents, Gadolinium Oxide, Superparamagnetic Iron Oxide and Liposomes.

(RODEO) The software package Spiral RODEO™ MRI (including a patented fat and ductal tissue suppression technology), developed from Aurora Imaging Technology Inc, improves the spatial resolution and sensitivity for cancer detection in breast MRI examinations.

See also Aurora® 15T Dedicated Breast MRI System.