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Spin Density
 
(N) The SI units is moles/m3.
Definition: The concentration of nuclei in tissue processing at the Larmor frequency in a given region; one of the principal determinants of the strength of the NMR signal from the region.
For water, there are about 1.1 x 105 moles of hydrogen per m3, or 0.11 moles of hydrogen/cm3.
The signal intensity measured is related to the square of the xy-magnetization, which in a SE pulse sequence is given by
Mxy = Mxy0(1-exp(-TR/T1)) exp(-TE/T2)
where Mxy0 = Mz0 is proportional to the proton or spin density, and corresponds to the z-magnetization present at zero time of the experiment when it is tilted into the xy-plane.
True spin density is not imaged directly, but must be calculated from signals received with different interpulse times. The spin density contrast can be generated by using a long TR and sampling the data immediately after the RF pulse (with a TE as short as possible).
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Magnetic resonance imaging
   by www.scholarpedia.org    
How Many? A Dictionary of Units of Measurement © Russ Rowlett and the University of North Carolina at Chapel Hill
Wednesday, 21 March 2001   by www.unc.edu    
How does the proton get its spin?
Wednesday, 17 February 2010   by www.physorg.com    
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Magnetic Resonance Imaging MRI
 
(MRI) Magnetic resonance imaging is a noninvasive medical imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field and body tissue to obtain images of slices/planes from inside the body. These magnets generate fields from approx. 2000 times up to 30000 times stronger than that of the Earth. The use of nuclear magnetic resonance principles produces extremely detailed pictures of the body tissue without the need for x-ray exposure and gives diagnostic information of various organs.
Measured are mobile hydrogen nuclei (protons are the hydrogen atoms of water, the 'H' in H20), the majority of elements in the body. Only a small part of them contribute to the measured signal, caused by their different alignment in the magnetic field. Protons are capable of absorbing energy if exposed to short radio wave pulses (electromagnetic energy) at their resonance frequency. After the absorption of this energy, the nuclei release this energy so that they return to their initial state of equilibrium.
This transmission of energy by the nuclei as they return to their initial state is what is observed as the MRI signal. The subtle differing characteristic of that signal from different tissues combined with complex mathematical formulas analyzed on modern computers is what enables MRI imaging to distinguish between various organs. Any imaging plane, or slice, can be projected, and then stored or printed.
The measured signal intensity depends jointly on the spin density and the relaxation times (T1 time and T2 time), with their relative importance depending on the particular imaging technique and choice of interpulse times. Any motion such as blood flow, respiration, etc. also affects the image brightness.
Magnetic resonance imaging is particularly sensitive in assessing anatomical structures, organs and soft tissues for the detection and diagnosis of a broad range of pathological conditions. MRI pictures can provide contrast between benign and pathological tissues and may be used to stage cancers as well as to evaluate the response to treatment of malignancies. The need for biopsy or exploratory surgery can be eliminated in some cases, and can result in earlier diagnosis of many diseases.

See also MRI History and Functional Magnetic Resonance Imaging (fMRI).
 
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Magnetization Value
 
(Mo) Equilibrium value of the magnetization;; directed along the direction of the static magnetic field. Proportional to spin density (N).
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Nuclear Magnetic Resonance ImagingMRI Resource Directory:
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Creation of images of objects such as the body by use of the nuclear magnetic resonance phenomenon. The immediate practical application involves imaging the distribution of hydrogen nuclei (protons) in the body. The image brightness in a given region depends on the spin density and the relaxation times, with their relative importance determined by the particular imaging technique employed. Image brightness is also affected by motion such as blood flow.

See also Zeugmatography and Magnetic Resonance Imaging MRI.
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Partial SaturationInfoSheet: - Sequences - 
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(PS) Excitation technique applying repeated RF pulses in times comparable to or shorter than T1. Incomplete T1 relaxation leads to reduction of the signal amplitude; there is the possibility of generating images with increased contrast between regions with different relaxation times.
Although partial saturation is also commonly referred to as saturation recovery, that term should properly be reserved for the particular case of partial saturation in which recovery after each excitation effectively takes place from true saturation. A GRE sequence where α = 90° is identical to the partial saturation or saturation recovery pulse sequence.
It does not directly produce images of T1. However, since the measured signal will depend on T1, the method generates contrast between regions with different relaxation times. If T2 and/or T2 effects are minimized through the use of a short echo time TE, the result is a T1 weighted image. It is not a T1 image due to the possible presence of spin density and T2 effects as well as the nonlinear dependence on T1.
The change in signal from a region resulting from a change in the interpulse time, TR, can be used to calculate T1 for the region.
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