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Multiple Spin Echo
 
A pulse sequence leading to the production of multiple spin echoes after an initial excitation.
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Spin Echo SequenceInfoSheet: - Sequences - 
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Spin Echo Timing Diagram (SE) The most common pulse sequence used in MR imaging is based of the detection of a spin or Hahn echo. It uses 90° radio frequency pulses to excite the magnetization and one or more 180° pulses to refocus the spins to generate signal echoes named spin echoes (SE).
In the pulse sequence timing diagram, the simplest form of a spin echo sequence is illustrated.
The 90° excitation pulse rotates the longitudinal magnetization (Mz) into the xy-plane and the dephasing of the transverse magnetization (Mxy) starts.
The following application of a 180° refocusing pulse (rotates the magnetization in the x-plane) generates signal echoes. The purpose of the 180° pulse is to rephase the spins, causing them to regain coherence and thereby to recover transverse magnetization, producing a spin echo.
The recovery of the z-magnetization occurs with the T1 relaxation time and typically at a much slower rate than the T2-decay, because in general T1 is greater than T2 for living tissues and is in the range of 100-2000 ms.
The SE pulse sequence was devised in the early days of NMR days by Carr and Purcell and exists now in many forms: the multi echo pulse sequence using single or multislice acquisition, the fast spin echo (FSE/TSE) pulse sequence, echo planar imaging (EPI) pulse sequence and the gradient and spin echo (GRASE) pulse sequence;; all are basically spin echo sequences.
In the simplest form of SE imaging, the pulse sequence has to be repeated as many times as the image has lines.
Contrast values:
PD weighted: Short TE (20 ms) and long TR.
T1 weighted: Short TE (10-20 ms) and short TR (300-600 ms)
T2 weighted: Long TE (greater than 60 ms) and long TR (greater than 1600 ms)
With spin echo imaging no T2* occurs, caused by the 180° refocusing pulse. For this reason, spin echo sequences are more robust against e.g., susceptibility artifacts than gradient echo sequences.

See also Pulse Sequence Timing Diagram to find a description of the components.
 
Images, Movies, Sliders:
 Shoulder Coronal T1 SE  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 Shoulder Axial T1 SE  Open this link in a new window
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Further Reading:
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Fast Spin Echo(.pdf)
Tuesday, 24 January 2006   by www.81bones.net    
Magnetic resonance imaging
   by www.scholarpedia.org    
FUNDAMENTALS OF MRI: Part I
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New MR sequence helps radiologists more accurately evaluate abnormalities of the uterus and ovaries
Thursday, 23 April 2009   by www.eurekalert.org    
MRI techniques improve pulmonary embolism detection
Monday, 19 March 2012   by medicalxpress.com    
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Low Angle Spin EchoInfoSheet: - Sequences - 
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Double Fast Spin EchoInfoSheet: - Sequences - 
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(DFSE) Simultaneously acquired T2 and density weighted TE in FSE echo images.
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Further Reading:
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BASIC PRINCIPLES OF MR IMAGING
   by spinwarp.ucsd.edu    
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Spin Echo Multi SliceInfoSheet: - Sequences - 
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(SEMS) This pulse sequence is composed of a 90° RF pulse followed by a 180° refocusing pulse. Both RF pulses are applied in the presence of a slice select gradient.
By choosing of different TR and TE, depending on the T1 and T2 values of the tissues, proton density, T1 weighted and T2 weighted images can be acquired.
The inversion recovery option enlarge the RF pulses with a 180° inverting pulse, applied a TI time before the beginning of the pulse sequence in order to manipulate image contrast.
See also Spin Echo Sequence.
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Further Reading:
  Basics:
Fast Spin Echo(.pdf)
Tuesday, 24 January 2006   by www.81bones.net    
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