(FRFSE, FR-FSE) The fast relaxation fast spin echo sequence provides high signal intensity of fluids even with short repetition times, and can be used with parallel imaging techniques for short breath hold imaging or respiratory gating for free-breathing, high isotropic resolution MR imaging. After signal decay at the end of the echo train, a negative 90° pulse align spins with long T2 from the transverse plane to the longitudinal plane, leading to a much faster recovery of tissues with long T2 time to the equilibrium and thus better contrast between tissues with long and short T2.
Fast relaxation FSE has advantages also for volumetric imaging as the TR can be substantially reduced and thus the scan time. The sequence can be post processed with maximum intensity projection, surface or volume rendering algorithms to visualize anatomical details in brain or spine MRI. Cerebro spinal fluid pulsation artifacts, often problematic in the cervical or thoracic spine may be reduced by radial sampling, in particular when combined with acquisitions of the PROPELLER type.

See also Fast spin echo, Driven Equilibrium.

(FA) The flip angle a is used to define the angle of excitation for a field echo pulse sequence. It is the angle to which the net magnetization is rotated or tipped relative to the main magnetic field direction via the application of a RF excitation pulse at the Larmor frequency. It is also referred to as the tip angle, nutation angle or angle of nutation.
The radio frequency power (which is proportional to the square of the amplitude) of the pulse is proportional to a through which the spins are tilted under its influence. Flip angles between 0° and 90° are typically used in gradient echo sequences, 90° and a series of 180° pulses in spin echo sequences and an initial 180° pulse followed by a 90° and a 180° pulse in inversion recovery sequences.

The occurrence of a low signal in regions of flow. For a spin echo sequence, this is caused in part by a lack of refocusing of blood, which is excited by the 90° pulse but not by the 180° pulse. For a gradient echo sequence, this is caused by the dephasing of blood signal.

Knee and shoulder MRI exams are the most commonly requested musculoskeletal MRI scans. Other MR imaging of the extremities includes hips, ankles, elbows, and wrists. Orthopedic imaging requires very high spatial resolution for reliable small structure definition and therefore places extremely high demands on SNR.
Exact presentation of joint pathology expects robust and reliable fat suppression, often under difficult conditions like off-center FOV, imaging at the edge of the field homogeneity or in regions with complex magnetic susceptibility.
MR examinations can evaluate meniscal dislocations, muscle fiber tears, tendon disruptions, tendinitis, and diagnose bone tumors and soft tissue masses. MR can also demonstrate acute fractures that are radiographically impossible to see. Evaluation of articular cartilage for traumatic injury or assessment of degenerative disease represents an imaging challenge, which can be overcome by high field MRI applications. Currently, fat-suppressed 3D spoiled gradient echo sequences and density weighted fast spin echo sequences are the gold-standard techniques used to assess articular cartilage.
Open MRI procedures allow the kinematic imaging of joints, which provides added value to any musculoskeletal MRI practice. This technique demonstrates the actual functional impingements or positional subluxations of joints. In knee MRI examinations, the kinematical patellar study can show patellofemoral joint abnormalities.

See also Open MRI, Knee MRI, Low Field MRI.

(IR) The inversion recovery pulse sequence produces signals, which represent the longitudinal magnetization existing after the application of a 180° radio frequency pulse that rotates the magnetization Mz into the negative plane. After an inversion time (TI - time between the starting 180° pulse and the following 90° pulse), a further 90° RF pulse tilts some or all of the z-magnetization into the xy-plane, where the signal is usually rephased with a 180° pulse as in the spin echo sequence. During the initial time period, various tissues relax with their intrinsic T1 relaxation time.
In the pulse sequence timing diagram, the basic inversion recovery sequence is illustrated. The 180° inversion pulse is attached prior to the 90° excitation pulse of a spin echo acquisition. See also the Pulse Sequence Timing Diagram. There you will find a description of the components.
The inversion recovery sequence has the advantage, that it can provide very strong contrast between tissues having different T1 relaxation times or to suppress tissues like fluid or fat. But the disadvantage is, that the additional inversion radio frequency RF pulse makes this sequence less time efficient than the other pulse sequences.

Contrast values:
PD weighted: TE: 10-20 ms, TR: 2000 ms, TI: 1800 ms
T1 weighted: TE: 10-20 ms, TR: 2000 ms, TI: 400-800 ms
T2 weighted: TE: 70 ms, TR: 2000 ms, TI: 400-800 ms

See also Inversion Recovery, Short T1 Inversion Recovery, Fluid Attenuation Inversion Recovery, and Acronyms for 'Inversion Recovery Sequence' from different manufacturers.