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 MIP            Maximum Intensity Projection 
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Maximum Intensity Projection
 
(MIP) MRA images can be processed by Maximum Intensity Projection to interactively create different projections. The MIP connects the high intensity dots of the blood vessels in three dimensions, providing an angiogram that can be viewed from any projection. Each point in the MIP represents the highest intensity experienced in that location on any partition within the imaging volume.
For complete interpretation the base slices should also be reviewed individually and with multiplanar reconstruction (MPR) software. The MIP can then be displayed in a CINE format or filmed as multiple images acquired from different projections. Although the maximum intensity projection (MIP) algorithm is sensitive to high signal from inflowing spins, it is also sensitive to high signal of any other etiology.
 
Images, Movies, Sliders:
 CE MRA of the Aorta  Open this link in a new window
    
SlidersSliders Overview

 CE-MRA of the Carotid Arteries  Open this link in a new window
    
SlidersSliders Overview

 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 CE-MRA of the Carotid Arteries Colored MIP  Open this link in a new window
    
SlidersSliders Overview

 TOF-MRA Circle of Willis Inverted MIP  Open this link in a new window
    

 
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• Related Searches:
    • Blood Pool Agents
    • Magnetic Resonance Cholangiopancreaticography
    • Staircase Artifact
    • Contrast Enhanced Magnetic Resonance Angiography
    • Postprocessing
 
Further Reading:
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State of the art in magnetic resonance imaging
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Blood Pool AgentsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Blood pool agents (intravascular contrast agents) remain in the blood for a prolonged time compared with conventional contrast agents, which diffuse quickly into the interstitial space. Magnetic resonance angiography (MRA), cardiovascular imaging, or contrast enhanced MRIs are possible over an hour or more. This advantage over conventional MRI contrast media allows also higher resolution MRA of several territories using respiratory or cardiac gating techniques with a single contrast bolus.
Different types of blood pool contrast agents:
Blood pool MRI contrast agents with their longer intravascular circulation can be designed to be targeted to necrotic myocardium, to assess myocardial viability, or tumor directed to provide better diagnostic information for various tumors. A disadvantage of the use of blood pool agents for MRA is that the separation of arteries and veins is more difficult because they are present in both and the overlapping of those vessels is disturbing. This can be solved by e.g. different MIP segmentation algorithms.

See also Necrosis Avid Contrast Agent, Tumor Specific Agents, Feruglose, Gadofosveset Trisodium (Vasovist), Ultrasmall Superparamagnetic Iron Oxide and Contrast Medium.
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• View the DATABASE results for 'Blood Pool Agents' (16).Open this link in a new window


• View the NEWS results for 'Blood Pool Agents' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Ablavar Prescribing Information
   by www.ablavar.com    
Lantheus Medical Imaging, Inc. Launches ABLAVAR™ (Gadofosveset Trisodium), a New Diagnostic Magnetic Resonance Angiography Agent
Wednesday, 20 January 2010   by www.radiopharm.com    
Blood-Pool Imaging Using Technetium-99m-Labeled Liposomes(.pdf)
   by jnm.snmjournals.org    
  News & More:
Multimodal Nanoparticles for Quantitative Imaging(.pdf)
Tuesday, 13 December 2011   by alexandria.tue.nl    
MAGNETIC RESONANCE IMAGING OF FOCAL LIVER LESIONS(.pdf)
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MRI Resources 
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Contrast Enhanced Magnetic Resonance AngiographyInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.MRI Resource Directory:
 - MRA -
 
(CE MRA) Contrast enhanced MR angiography is based on the T1 values of blood, the surrounding tissue, and paramagnetic contrast agent.
T1-shortening contrast agents reduces the T1 value of the blood (approximately to 50 msec, shorter than that of the surrounding tissues) and allow the visualization of blood vessels, as the images are no longer dependent primarily on the inflow effect of the blood. Contrast enhanced MRA is performed with a short TR to have low signal (due to the longer T1) from the stationary tissue, short scan time to facilitate breath hold imaging, short TE to minimize T2* effects and a bolus injection of a sufficient dose of a gadolinium chelate.
Images of the region of interest are performed with 3D spoiled gradient echo pulse sequences. The enhancement is maximized by timing the contrast agent injection such that the period of maximum arterial concentration corresponds to the k-space acquisition. Different techniques are used to ensure optimal contrast of the arteries e.g., bolus timing, automatic bolus detection, bolus tracking, care bolus. A high resolution with near isotropic voxels and minimal pulsatility and misregistration artifacts should be striven for. The postprocessing with the maximum intensity projection (MIP) enables different views of the 3D data set.
Unlike conventional MRA techniques based on velocity dependent inflow or phase shift techniques, contrast enhanced MRA exploits the gadolinium induced T1-shortening effects. CE MRA reduces or eliminates most of the artifacts of time of flight angiography or phase contrast angiography. Advantages are the possibility of in plane imaging of the blood vessels, which allows to examine large parts in a short time and high resolution scans in one breath hold. CE MRA has found a wide acceptance in the clinical routine, caused by the advantages:
3D MRA can be acquired in any plane, which means that greater vessel coverage can be obtained at high resolution with fewer slices (aorta, peripheral vessels);
the possibility to perform a time resolved examination (similarly to conventional angiography);
no use of ionizing radiation; paramagnetic agents have a beneficial safety.
 
Images, Movies, Sliders:
 CE-MRA of the Carotid Arteries  Open this link in a new window
    
SlidersSliders Overview

 CE MRA of the Aorta  Open this link in a new window
    
SlidersSliders Overview

 CE-MRA of the Carotid Arteries Colored MIP  Open this link in a new window
    
SlidersSliders Overview

 
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• View the DATABASE results for 'Contrast Enhanced Magnetic Resonance Angiography' (14).Open this link in a new window


• View the NEWS results for 'Contrast Enhanced Magnetic Resonance Angiography' (2).Open this link in a new window.
 
Further Reading:
  Basics:
Contrast-Enhanced MR Angiography(.pdf)
   by ric.uthscsa.edu    
CONTRAST ENHANCED MR ANGIOGRAPHY – PRINCIPLES, APPLICATIONS, TIPS AND PITFALLS(.pdf)
  News & More:
CONTRAST-ENHANCED MRA OF THE CAROTIDS(.pdf)
PERIPHERAL VASCULAR MAGNETIC RESONANCE ANGIOGRAPHY(.pdf)
CONTRAST ENHANCED MRI OF THE LIVER STATE-OF-THE-ART(.pdf)
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Fast Imaging Employing Steady State AcquisitionInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
(FIESTA) The fast imaging employing steady state acquisition sequence provides images of fluid filled structures with very short acquisition times. The FIESTA sequence uses the T2 steady state contrast mechanism to provide high SNR images with strong signal from fluid tissues while suppressing background tissue for contrast and anatomic detail of small structures. In addition, the ultra short TR and TE enable extremely short acquisition times - shorter than FSE - and the images can be post processed using MIP, volume rendering, or 3D navigator techniques.

See Steady State Free Precession.
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MRI Resources 
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Magnetic Resonance CholangiopancreaticographyMRI Resource Directory:
 - MRCP -
 
(MRCP) This MR imaging technique takes advantage of the high signal intensity of body fluids and acquires heavy T2 weighted images of the gall bladder, the pancreas and parts of the liver. Due to the T2 weighting, the liver and other solid parenchyma are signal suppressed and only fluid-filled structures in addition to the gall bladder, the bile and pancreatic ducts retain important signal intensity. Hepatobiliary contrast agents (e.g. Gadoxetic Acid, CMC 001) can be useful for enhancement of the bile ducts and better imaging of the biliary tract.
A 2D cholangiogram, often only one thick slice (a volume with a thickness of 4 - 8 cm, mostly coronal planned) or 5 - 6 radial placed slices, shows a view like single slices. If a 3D acquisition is used, the postprocessing function maximum intensity projection (MIP) can show reconstructions from multiple sides.
Radiology-tip.comradBiliary Contrast Agents
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Medical-Ultrasound-Imaging.comGallbladder Ultrasound
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• View the DATABASE results for 'Magnetic Resonance Cholangiopancreaticography' (3).Open this link in a new window

 
Further Reading:
  News & More:
Perspectum and Nuance Collaborate to Scale Access to AI-Enabled Integrated Digital Care Platforms to Improve Patient Care for Metabolic Disease
Friday, 9 December 2022   by www.itnonline.com    
MRI Resources 
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