Diffusion weighted imaging can be performed similar to the phase contrast angiography sequence. The gradients must be increased in amplitude to depict the much slower motions of molecular diffusion in the body.
While a T1 weighted MRI pulse sequence is diffusion sensitive, a quantitative diffusion pulse sequence was introduced by Steijskal and Tanner. Its characteristic features are two strong symmetrical gradient lobes placed on either side of the 180° refocusing pulse in a spin echo sequence. These symmetrical gradient lobes have the sole purpose of enhancing dephasing of spins, thereby accelerating intravoxel incoherent motion (IVIM) signal loss.
Dephasing is proportional to the square of the time (diffusion time) during which the gradients are switched on and the strength of the applied gradient field. Therefore, the use of high field gradient systems with faster and more sensitive sequences, make diffusion weighting more feasible.
Areas in which the protons diffuse rapidly (swollen cells in early stroke, less restriction to diffusion) will show an increased signal when the echo is measured relative to areas in which diffusion is restricted. For increased accuracy of diffusion measurement and image enhancement, useful motion correction techniques such as navigator echo and other methods should be used. In addition to this, applying the b-value calculated by the strength and duration of motion probing gradients with a high rate of accuracy is very important.

See also Apparent Diffusion Coefficient, ADC Map, Lattice Index Map.

(IR) The inversion recovery pulse sequence produces signals, which represent the longitudinal magnetization existing after the application of a 180° radio frequency pulse that rotates the magnetization Mz into the negative plane. After an inversion time (TI - time between the starting 180° pulse and the following 90° pulse), a further 90° RF pulse tilts some or all of the z-magnetization into the xy-plane, where the signal is usually rephased with a 180° pulse as in the spin echo sequence. During the initial time period, various tissues relax with their intrinsic T1 relaxation time.
In the pulse sequence timing diagram, the basic inversion recovery sequence is illustrated. The 180° inversion pulse is attached prior to the 90° excitation pulse of a spin echo acquisition. See also the Pulse Sequence Timing Diagram. There you will find a description of the components.
The inversion recovery sequence has the advantage, that it can provide very strong contrast between tissues having different T1 relaxation times or to suppress tissues like fluid or fat. But the disadvantage is, that the additional inversion radio frequency RF pulse makes this sequence less time efficient than the other pulse sequences.

Contrast values:
PD weighted: TE: 10-20 ms, TR: 2000 ms, TI: 1800 ms
T1 weighted: TE: 10-20 ms, TR: 2000 ms, TI: 400-800 ms
T2 weighted: TE: 70 ms, TR: 2000 ms, TI: 400-800 ms

See also Inversion Recovery, Short T1 Inversion Recovery, Fluid Attenuation Inversion Recovery, and Acronyms for 'Inversion Recovery Sequence' from different manufacturers.

The schematic figures of a pulse sequence timing diagram illustrate the steps of basic hardware activity that are incorporated into a pulse sequence. Time during sequence execution is indicated along the horizontal axes. Each line belongs to a different hardware component. One line is needed for the radio frequency transmitter and also one for each gradient (G_s = slice selection gradient x, G_f = phase encoding gradient y, G_f = frequency encoding gradient z, also called readout gradient).
In picture 1, a timing diagram for a 2D pulse sequence is shown.
Slice selection and signal detection are repeated in duration, relative timing and amplitude, each time the sequence is repeated. A single phase encoding component is present each time the sequence is executed.
Additional lines are added for ADC (Analog to Digital Converter) and sampling. A gradient pulse is shown as a deviation above or below the horizontal line. Simultaneous component activities such as the RF pulse and slice selection gradient are indicated as a non-zero deviation from both lines at the same horizontal position. Simple deviations from zero show constant amplitude gradient pulse. Gradient amplitudes that change during the measurement, e.g. phase encoding are represented as hatched regions.

The second picture shows a timing diagram for a 3D pulse sequence.
Volume excitation and signal detection are repeated in duration, relative timing and amplitude, each time the sequence is repeated. Two phase encoding components are present, one in the phase encoding direction and the other in slice selection direction (irrespectively incremented in amplitude) in each time the sequence is executed. A description of the comparison of hardware activity between different pulse sequences.

Spoiled gradient echo sequences use a spoiler gradient on the slice select axis during the end module to destroy any remaining transverse magnetization after the readout gradient, which is the case for short repetition times.
As a result, only z-magnetization remains during a subsequent excitation. This types of sequences use semi-random changes in the phase of radio frequency pulses to produce a spatially independent phase shift.
Companies use different acronyms to describe certain techniques.

Different terms for these gradient echo pulse sequences:
CE-FFE-T1 Contrast Enhanced Fast Field Echo with T1 Weighting,
GFE Gradient Field Echo,
FLASH Fast Low Angle Shot,
PS Partial Saturation,
RF spoiled FAST RF Spoiled Fourier Acquired Steady State Technique,
RSSARGE Radio Frequency Spoiled Steady State Acquisition Rewound Gradient Echo
S-GRE Spoiled Gradient Echo,
SHORT Short Repetition Techniques,
SPGR Spoiled Gradient Recalled (spoiled GRASS),
STAGE T1W T1 weighted Small Tip Angle Gradient Echo,
T1-FAST T1 weighted Fourier Acquired Steady State Technique,
T1-FFE T1 weighted Fast Field Echo.
In this context, 'contrast enhanced' refers to the pulse sequence, it does not mean enhancement with a contrast agent.

The gradient recalled echo MRI sequence generates gradient echoes as a consequence of echo refocusing. The initial slice selective RF pulse applied to the tissue is less than 90° (typically rotation angles are between 10° and 90°). Immediately after this RF pulse, the spins begin to dephase.
Instead of a refocusing 180° RF pulse, reversing the gradient polarity produces a gradient echo. A negative phase encoding gradient and a dephasing frequency encoding gradient are used simultaneous. The switch on of the frequency encoding gradient produces an echo caused by refocusing of the dephasing, which is caused by the dephasing gradient.
TR and flip angle together control the T1, and TE control T2* weighting.