(PS) Excitation technique applying repeated RF pulses in times comparable to or shorter than T1. Incomplete T1 relaxation leads to reduction of the signal amplitude; there is the possibility of generating images with increased contrast between regions with different relaxation times.
Although partial saturation is also commonly referred to as saturation recovery, that term should properly be reserved for the particular case of partial saturation in which recovery after each excitation effectively takes place from true saturation. A GRE sequence where α = 90° is identical to the partial saturation or saturation recovery pulse sequence.
It does not directly produce images of T1. However, since the measured signal will depend on T1, the method generates contrast between regions with different relaxation times. If T2 and/or T2 effects are minimized through the use of a short echo time TE, the result is a T1 weighted image. It is not a T1 image due to the possible presence of spin density and T2 effects as well as the nonlinear dependence on T1.
The change in signal from a region resulting from a change in the interpulse time, TR, can be used to calculate T1 for the region.

(RE MRI) There are several approaches to speeding up the MRI data acquisition process by repeating the excitation by RF pulses in times short compared to T1, typically using small flip angles and gradient echo refocusing. When TR is also on the order of or shorter than T2, the repeated RF pulses will tend to refocus transverse magnetization remaining from prior excitations, setting up a condition of steady state free precession, and a dependence of signal strength (and image contrast) on both T1 and T2.
This can be modified in various ways, particularly:
1) to spoil the tendency to build up a steady state by reducing coherence between excitations, e.g. by variation of the phase or timing of consecutive RF pulses or of the strength of spoiler gradient pulses, thus increasing the relative dependence of signal strength on T1 or
2) acquire the signal when it is refocusing immediately prior to the next RF pulse, thus increasing the relative dependence of signal strength on T2.

See also Ultrafast Gradient Echo Sequence.

MR imaging technique in which the spin echo is used rather than the FID. The proper selection of the echo and repetition time of the pulse sequence can help to control the amount of T1 or T2 contrast present in the image. Spin echo imaging can be used to create images that depend strongly on T2 if TE has a value on the order of or greater than T2 of the relevant image details. The spin echoes can be produced as a train of multiple echoes, e.g. using the CPMG pulse sequence.

See also Spin Echo Sequence.

This superparamagnetic oral contrast agent consists of large iron oxide particles, coated with insoluble material. Abdoscan® particles have a mean diameter no less than 300 nm. Gastrointestinal superparamagnetic contrast agents are used for negative bowel enhancement.

Abdoscan® was approved in Europe but was taken off the market in 2000, and all sales stopped by the end of 2002.

From Aurora Imaging Technology, Inc.;
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