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Magnetic resonance imaging is a radiological diagnostic procedure without X-rays.

Magnetic resonance imaging, see also: MRI history, medical imaging, nuclear magnetic resonance, spin, precession, T1 time, T2 time, MRI equipment, MRI devices, MRI coils, MRI sequences, MRI contrast agents.

MRI resources, MRI congresses, and MRI news.
 
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Further Reading:
  Basics:
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
  News & More:
MRI for Patients with Cardiac Device, Covered
Thursday, 3 October 2019   by www.aapc.com    
Bringing More Value to Imaging Departments With MRI
Friday, 4 October 2019   by www.itnonline.com    
The world's strongest MRI machines are pushing human imaging to new limits
Wednesday, 31 October 2018   by www.nature.com    
MRI Resources 
Devices - Jobs pool - Raman Spectroscopy - Patient Information - Shoulder MRI - Blood Flow Imaging
 
MRI History
 
Sir Joseph Larmor (1857-1942) developed the equation that the angular frequency of precession of the nuclear spins being proportional to the strength of the magnetic field. [Larmor relationship]
In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
In 1975, Richard Ernst introduced 2D NMR using phase and frequency encoding, and the Fourier Transform. Instead of Paul Lauterbur's back-projection, he timely switched magnetic field gradients ('NMR Fourier Zeugmatography'). [This basic reconstruction method is the basis of current MRI techniques.]
1977/78: First images could be presented. A cross section through a finger by Peter Mansfield and Andrew A. Maudsley. Peter Mansfield also could present the first image through the abdomen.
In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
In 1984, FONAR Corporation receives FDA approval for its first MRI scanner.
1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH (fast low angle shot) sequence.
1988: Schering's MAGNEVIST gets its first approval by the FDA.
In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
 
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• View the NEWS results for 'MRI History' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
Fonar Our History
   by www.fonar.com    
  News & More:
Scientists win Nobels for work on MRI
Tuesday, 10 June 2003   by usatoday30.usatoday.com    
2001 Lemelson-MIT Lifetime Achievement Award Winner
   by web.mit.edu    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
MRI Resources 
Stimulator pool - Examinations - Patient Information - Knee MRI - Most Wanted - MRI Centers
 
Macroscopic Magnetization Vector
 
Net magnetic moment per unit volume (a vector quantity) of a sample in a given region, considered as the integrated effect of all the individual microscopic nuclear magnetic moments.
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Magnetic Resonance
 
(MR) Resonance phenomenon resulting in the absorption and/or emission of electromagnetic energy by nuclei (for that reason also nuclear magnetic resonance) or electrons in a static magnetic field, after excitation by a suitable RF magnetic field.
The peak resonance frequency is proportional to the magnetic field, and is given by the Larmor equation. Only unpaired electrons or nuclei with a spin exhibit magnetic resonance. The absorption or emission of energy by atomic nuclei in an external magnetic field after the application of RF excitation pulses using frequencies, which satisfy the conditions of the Larmor equation.
The magnetic resonance phenomenon may be used in one of these ways:
By manipulation of the external field (application of gradient fields), the resonance frequency can become dependent on spatial location, and hence images may be generated (MRI).
The effect of the electron cloud in any atom or molecule is to slightly shield the nucleus from the external field, thus giving any chemical species a characteristic frequency. This gives rise to 'spectra' where nuclei in a molecule give rise to specific signals, thus facilitating the detection of individual chemicals by means of their frequency spectra (MRS)
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Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
  News & More:
The 2003 Nobel Prize in Physiology or Medicine
2003   by www.nobel.se    
MRI Resources 
Cardiovascular Imaging - Musculoskeletal and Joint MRI - Equipment - Non-English - Most Wanted - Homepages
 
Magnetic Resonance Imaging MRI
 
(MRI) Magnetic resonance imaging is a noninvasive medical imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field and body tissue to obtain images of slices/planes from inside the body. These magnets generate fields from approx. 2000 times up to 30000 times stronger than that of the Earth. The use of nuclear magnetic resonance principles produces extremely detailed pictures of the body tissue without the need for x-ray exposure and gives diagnostic information of various organs.
Measured are mobile hydrogen nuclei (protons are the hydrogen atoms of water, the 'H' in H20), the majority of elements in the body. Only a small part of them contribute to the measured signal, caused by their different alignment in the magnetic field. Protons are capable of absorbing energy if exposed to short radio wave pulses (electromagnetic energy) at their resonance frequency. After the absorption of this energy, the nuclei release this energy so that they return to their initial state of equilibrium.
This transmission of energy by the nuclei as they return to their initial state is what is observed as the MRI signal. The subtle differing characteristic of that signal from different tissues combined with complex mathematical formulas analyzed on modern computers is what enables MRI imaging to distinguish between various organs. Any imaging plane, or slice, can be projected, and then stored or printed.
The measured signal intensity depends jointly on the spin density and the relaxation times (T1 time and T2 time), with their relative importance depending on the particular imaging technique and choice of interpulse times. Any motion such as blood flow, respiration, etc. also affects the image brightness.
Magnetic resonance imaging is particularly sensitive in assessing anatomical structures, organs and soft tissues for the detection and diagnosis of a broad range of pathological conditions. MRI pictures can provide contrast between benign and pathological tissues and may be used to stage cancers as well as to evaluate the response to treatment of malignancies. The need for biopsy or exploratory surgery can be eliminated in some cases, and can result in earlier diagnosis of many diseases.

See also MRI History and Functional Magnetic Resonance Imaging (fMRI).
 
Images, Movies, Sliders:
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Courtesy of  Robert R. Edelman

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Courtesy of  Robert R. Edelman

 
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Further Reading:
  Basics:
Bringing More Value to Imaging Departments With MRI
Friday, 4 October 2019   by www.itnonline.com    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
On the Horizon - Next Generation MRI
Wednesday, 23 October 2013   by thefutureofthings.com    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
  News & More:
High-resolution MRI enables direct imaging of neuronal activity - DIANA – direct imaging of neuronal activity
Friday, 18 November 2022   by physicsworld.com    
New MRI technique can 'see' molecular changes in the brain
Thursday, 5 September 2019   by medicalxpress.com    
How new MRI technology is transforming the patient experience
Tuesday, 14 May 2019   by newsroom.gehealthcare.com    
Metamaterials boost sensitivity of MRI machines
Thursday, 14 January 2016   by www.eurekalert.org    
MRI technique allows study of wrist in motion
Monday, 6 January 2014   by www.healthimaging.com    
New imaging technology promising for several types of cancer
Thursday, 29 August 2013   by medicalxpress.com    
MRI method for measuring MS progression validated
Thursday, 19 December 2013   by www.eurekalert.org    
MRI Resources 
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